Publications from the Department of Biomedical and Pharmaceutical Sciences faculty at the University of Rhode Island.

Follow

Submissions from 2015

PDF

Design, Synthesis, Antiviral Activity, and Pre-Formulation Development of Poly-L-Arginine-Fatty Acyl Derivatives of Nucleoside Reverse Transcriptase Inhibitors, Bhanu P. Pemmaraju, Swapnil Malekar, Hitesh K. Agarwal, Rakesh K. Tiwari, Donghoon Oh, Gustavo F. Doncel, David R. Worthen, and Keykavous Parang

PDF

The Cranberry Flavonoids PAC DP-9 and Quercetin Aglycone Induce Cytotoxicity and Cell Cycle Arrest and Increase Cisplatin Sensitivity in Ovarian Cancer Cells, Yifei Wang, Alex Han, Eva Chen, Rakesh K. Singh, Clinton O. Chichester, Richard G. Moore, Ajay P. Singh, and Nicholi Vorsa

PDF

Deficiency in Nrf2 transcription factor decreases adipose tissue mass and hepatic lipid accumulation in leptin‐deficient mice, Jialin Xu, Ajay C. Donepudi, Vijay R. More, Supriya R. Kulkarni, Liya Li, Liangran Guo, Bingfang Yan, Tapan Chatterjee, Neal Weintraub, and Angela L. Slitt

PDF

Laser mimicking mosquito bites for skin delivery of malaria sporozoite vaccines, Chang Zhou, Xinyuan Chen, Qi Zhang, Ji Wang, and Mei X. Wu

Submissions from 2014

PDF

Facile, Regio- and Diastereoselective Synthesis of Spiro-Pyrrolidine and Pyrrolizine Derivatives and Evaluation of Their Antiproliferative Activities, Abdulrahman I. Almansour, Raju Suresh Kumar, Farzana Beevi, Amir Nasrolahi Shirazi, Hasnah Osman, Rusli Ismail, Tan Soo Choon, Brian Sullivan, Kellen McCaffrey, Alaa Nahhas, Keykavous Parang, and Mohamed Ashraf Ali

PDF

Lactate Dehydrogenase Like Crystallin: A Potentially Protective Shield for Indian Spiny-Tailed Lizard (Uromastyx hardwickii) Lens Against Environmental Stress?, Ambreen Atta, Amber Ilyas, Zehra Hashim, Aftab Ahmed, and Shamshad Zarina

PDF

Clinical Implication of Changes in Serum Adiponectin in Patients with Hepatogenic Diabetes, Zhongying Bao, Xiaodong Yuan, Shuhong Duan, and Xiaoqun Dong

PDF

Infantile postnatal exposure to lead (Pb) enhances tau expression in the cerebral cortex of aged mice: Relevance to AD, Syed Waseem Bihaqi, Azadeh Bahmani, Abdu Adem, and Nasser H. Zawia

PDF

Infantile exposure to lead and late-age cognitive decline: Relevance to AD, Syed Waseem Bihaqi, Azadeh Bahmani, Gehad M. Subaiea, and Nasser H. Zawia

PDF

Synthesis and Evaluation of c-Src Kinase Inhibitory Activity of Pyridin-2(1H)-one Derivatives, Karam Chand, Suchita Prasad, Rakesh K. Tiwari, Amir N. Shirazi, Sumit Kumar, Keykavous Parang, and Sunil K. Sharma

PDF

Tea polyphenols induced apoptosis of breast cancer cells by suppressing the expression of Survivin, Xuesong Chen, Yu Li, Qiushi Lin, Yan Wang, Hong Sun, Jian Wang, Guoquan Cui, Li Cai, and Xiaoqun Dong

PDF

Baseline Staging Tests Based on Molecular Subtype is Necessary for Newly Diagnosed Breast Cancer, Xuesong Chen, Lichun Sun, Yingying Cong, Tingting Zhang, Qiushi Lin, Qingwei Meng, Hui Pang, Yanbin Zhao, Yu Li, Li Cai, and Xiaoqun Dong

PDF

Low-dose chemotherapy of hepatocellular carcinoma through triggered-release from bilayer-decorated magnetoliposomes, Yanjing Chen, Yuan Chen, Da Xiao, Arijit Bose, Ruitang Deng, and Geoffrey D. Bothun

PDF

Carbocyclodipeptides as modified nucleosides: synthesis and anti-HIV activities, Bhupender S. Chhikara, M. Sudershan Rao, V. Kameshwara Rao, Anil Kumar, Karen W. Buckheit, Robert W. Buckheit Jr., and Keykavous Parang

PDF

Aspartate β-Hydroxylase Expression Promotes a Malignant Pancreatic Cellular Phenotype, Xiaoqun Dong, Qiushi Lin, Arihiro Aihara, Yu Li, Chiung-Kuei Huang, Waihong Chung, Qi Tang, Xuesong Chen, Rolf Carlson, Christina Nadolny, Gregory Gabriel, Mark Olsen, and Jack Wands

PDF

Synthesis of 4-aryl-6-indolylpyridine-3-carbonitriles and evaluation of their antiproliferative activity, Naglaa Salem El-Sayed, Amir Nasrolahi Shirazi, Magda Goda El-Meligy, Ahmed Kamel El-Ziaty, David C. Rowley, Jiadong Sun, Zenat Adeeb Nagib, and Keykavous Parang

PDF

Biomarkers of TGF-β Signaling Pathway and Prognosis of Pancreatic Cancer, Milind Javle, Yanan Li, Dongfeng Tan, Xiaoqun Dong, Ping Chang, Siddhartha Kar, and Donghui Li

PDF

LRH1 as a driving factor in pancreatic cancer growth, Qiushi Lin, Arihiro Aihara, Waihong Chung, Yu Li, Zheping Huang, Xuesong Chen, Shaofan Weng, Rolf I. Carlson, Jack R. Wands, and Xiaoqun Dong

PDF

Serum Helicobacter pylori NapA antibody as a potential biomarker for gastric cancer, Jingjing Liu, Huimin Liu, Tingting Zhang, Xiyun Ren, Christina Nadolny, Xiaqun Dong, Lina Huang, Kexin Yuan, Wenjing Tian, and Yunhe Jia

PDF

Self-Assembly of Peptides to Nanostructures, Dindyal Mandal, Amir Nasrolahi Shirazi, and Keykavous Parang

PDF

Vibrio vulnificus MO6-24/O Lipopolysaccharide Stimulates Superoxide Anion, Thromboxane B2, Matrix Metalloproteinase-9, Cytokine and Chemokine Release by Rat Brain Microglia in Vitro, Alejandro M.S. Mayer, Mary L. Hall, Michael Holland, Cristina De Castro, Antonio Molinaro, Monica Aldulescu, Jeffrey Frenkel, Lauren Ottenhoff, David Rowley, and Jan Powell

PDF

G Protein Beta 5 Is Targeted to D2-Dopamine Receptor-Containing Biochemical Compartments and Blocks Dopamine-Dependent Receptor Internalization, J. Christopher Octeau, Joseph M. Schrader, Ikuo Masuho, Meenakshi Sharma, Christopher Aiudi, Ching-Kang Chen, Abraham Kovoor, and Jeremy Celver

PDF

Synthesis and Biological Evaluation of 5′-O-Dicarboxylic Fatty Acyl Monoester Derivatives of Anti-HIV Nucleoside Reverse Transcriptase Inhibitors, Bhanu Pemmaraju, Hitesh K. Agarwal, Donghoon Oh, Karen W. Buckheit, Robert W. Buckheit Jr., Rakesh Tiwari, and Keykavous Parang

PDF

Targeted search for actinomycetes from nearshore and deep-sea marine sediments, Alejandra Prieto-Davó, Luis J. Villarreal-Gómez, Stephanie Forschner-Dancause, Alan T. Bull, James E.M. Stach, David C. Smith, David C. Rowley, and Paul R. Jensen

PDF

Differential Fmo3 gene expression in various liver injury models involving hepatic oxidative stress in mice, Swetha Rudraiah, Jamie E. Moscovitz, Ajay C. Donepudi, Sarah N. Campion, Angela L. Slitt, Lauren M. Aleksunes, and José E. Manautou

PDF

A Polymorphic Microdeletion in the RGS9 Gene Suppresses PTB Binding and Associates with Obesity, Chong Shen, Meenakshi Sharma, Daniel C. Reid, Pengtao Li, Jeremy Celver, Norhashimah Abu Seman, Jinfeng Chen, Senthil K. Vasan, Hairu Wang, Tianwei Gu, Ying Liu, Wan Nazaimoon Wan Mohamud, Hongbing Shen, Kerstin Brismar, William G. Fairbrother, Abraham Kovoor, and Harvest F. Gu

PDF

Cranberry (Vaccinium macrocarpon) oligosaccharides decrease biofilm formation by uropathogenic Escherichia coli, Jiadong Sun, Jannie P.J. Marais, Christina Khoo, Kerry L. LaPlante, Rebecca M. Vejborg, Michael Givskov, Tim Tolker-Nielsen, Navindra P. Seeram, and David C. Rowley

PDF

Circulating microRNAs in Pancreatic Juice as Candidate Biomarkers of Pancreatic Cancer, Jin Wang, Massimo Raimondo, Sushovan Guha, Jinyun Chen, Lixia Diao, Xiaoqun Dong, Michael B. Wallace, Ann M. Killary, Marsha L. Frazier, Timothy A. Woodward, Jing Wang, and Subrata Sen

PDF

rs744166 Polymorphism of the STAT3 Gene is Associated with Risk of Gastric Cancer in a Chinese Population, Kevin Yuan, Huimin Liu, Lina Huang, Xiyun Ren, Jingjing Liu, Xiaoqun Dong, Wenjing Tian, and Yunhe Jia

Submissions from 2013

PDF

Epigenetics: A novel therapeutic approach for the treatment of Alzheimer's disease, Lina Adwan and Nasser H. Zawia

PDF

Pregnancy Represses Induction of Efflux Transporters in Livers of Type I Diabetic Mice, Lauren M. Aleksunes, Jialin Xu, Eugenia Lin, Xia Wen, Michael J. Goedken, and Angela L. Slitt

PDF

Effects of Developmental Deltamethrin Exposure on White Adipose Tissue Gene Expression, Laura E. Armstrong, Maureen V. Driscoll, Vijay R. More, Ajay C. Donepudi, Jialin Xu, Angela Baker, Lauren M. Aleksunes, Jason R. Richardson, and Angela Slitt

PDF

Enhanced taupathy and AD-like pathology in aged primate brains decades after infantile exposure to lead (Pb), Syed Waseem Bihaqi and Nasser H. Zawia

PDF

Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome, Cong Cao, Mengia S. Rioult-Pedotti, Paolo Migani, Crystal J. Yu, Rakesh Tiwari, Keykavous Parang, Mark R. Spaller, Dennis J. Goebel, and John Marshall

PDF

Bile salt export pump is dysregulated with altered farnesoid X receptor isoform expression in patients with hepatocellular carcinoma, Yuan Chen, Xiulong Song, Leila Valanejad, Alexander Vasilenko, Vijay More, Xi Qiu, Weikang Chen, Yurong Lai, Angela L. Slitt, Matthew Stoner, Bingfang Yan, and Ruitang Deng

PDF

Chiral cationic polyamines for chiral microcapsules and siRNA delivery, Justin Gharavi, Patricks Marks, Kelly Moran, Brett Kingsborough, Ruchi Verma, Yuan Chen, Ruitang Deng, and Mindy Levine

PDF

A Comparative Study of Hollow Copper Sulfide Nanoparticles and Hollow Gold Nanospheres on Degradability and Toxicity, Laingran Guo, Irene Panderi, Daisy D. Yan, Kevin Szulak, Yajuan Li, Yi-Tzai Chen, Hang Ma, Daniel B. Niesen, Navindra P. Seeram, Aftab Ahmed, Bingfang Yan, Dionysios Pantazatos, and Wei Lu

PDF

Probiotic Strains for Shellfish Aquaculture: Protection of Eastern Oyster, Crassostrea virginica, Larvae and Juveniles Againsl Bacterial Challenge, Murni Karim, Wenjing Zhao, David C. Rowley, David R. Nelson, and Marta Gomez-Chiarri

PDF

Effect of Caloric Restriction and AMPK Activation on Hepatic Nuclear Receptor, Biotransformation Enzyme, and Transporter Expression in Lean and Obese Mice, Supriya R. Kulkarni, Jialin Xu, Ajay C. Donepudi, Wei Wei, and Angela L. Slitt

PDF

Caloric Restriction-Mediated Induction of Lipid Metabolism Gene Expression in Liver is Enhanced by Keap1-Knockdown, Supriya R. Kullkarni, Laura E. Armstrong, and Angela L. Slitt

PDF

Self-Assembled Surfactant Cyclic Peptide Nanostructures as Stabilizing Agents, Dindyal Mandal, Rakesh K. Tiwari, Amir Nasrolahi Shirazi, Donghoon Oh, Guofeng Ye, Antara Banarjee, Arpita Yadav, and Keykavous Parang

PDF

Keap1 knockdown increases markers of metabolic syndrome after long-term high fat diet feeding, Vijay R. More, Jialin Xu, Prajakta C. Shimpi, Clyde Belgrave, James P. Luyendyk, Masayuki Yamamoto, and Angela L. Slitt

PDF

Synthesis and Evaluation of Cytotoxic Activity of Substituted N-(9-oxo-9H-xanthen-4-yl)benzenesulfonamides, Somayeh Motavallizadeh, Asal Asal Fallah-Taftia, Saeedeh Maleki, Amir Nasrolahi Shirazi, Mahboobeh Pordeli, Maliheh Safavi, Sussan Kabudanian Ardestani, Shaaban Asd, Rakesh Tiwari, Donghoon Oh, Abbas Shafiee, Alireza Foroumadi, Keykavous Parang, and Tahmineh Akbarzadeh

PDF

Synthesis and antiproliferative activities of quebecol and its analogs, Kasiviswanadharaju Pericherla, Amir Nasrolahi Shirazi, V. Kameshwara Rao, Rakesh K. Tiwari, Nicholas DaSilva, Kellen T. McCaffrey, Yousef A. Beni, Antonion González-Sarrías, Navindra P. Seeram, Keykavous Parang, and Anil Kumar

PDF

A Simple and Efficient Synthesis of 2,3-Diarylnaphthofurans using Sequential Hydroarylation/Heck Oxyarylation, V. Kameshwara Rao, Gamesh M. Shelke, Rakesh Tiwari, Keykavous Parang, and Anil Kumar

PDF

Copper(II) triflate-mediated synthesis of 1,3,5-triarylpyrazoles in [bmim][PF6] ionic liquid and evaluation of their anticancer activities, V. Kameshwara Rao, Rakesh Tiwari, Bhupender S. Chhikara, Amir Nasrolahi Shirazi, Keykavous Parang, and Anil Kumar

PDF

Cellular and Organismal Toxicity of the Anti-Cancer Small Molecule, Tolfenamic Acid: A Pre-Clinical Evaluation, Umesh T. Sankpal, Chris M. Lee, Sarah F. Connelly, Omer Kayaleh, Don Eslin, Robert Sutphin, Steven Goodison, Lina Adwan, Nasser H. Zawia, Lenard M. Lichtenberger, and Riyaz Basha

PDF

Plasma Membrane Compartmentalization of D2 Dopamine Receptors, Meenakshi Sharma, Jeremy Celver, J. Christopher Octeau, and Abraham Kovoor

PDF

Peptide-Amphiphile Containing Arginine and Fatty Acyl Chains as Molecular Transporters, Amir Nasrolahi Shirazi, Donghoon Oh, Rakesh Kumar Tiwari, Brian Sullivan, Anju Gupta, Geoffrey D. Bothun, and Keykavous Parang

PDF

Cyclic peptides containing tryptophan and arginine as Src kinase inhibitors, Amir Nasrolahi Shirazi, Rakesh Kumar Tiwari, Alex Brown, Dindyal Mandal, Gongqin Sun, and Keykavous Parang

PDF

Efficient Delivery of Cell Impermeable Phosphopeptides by a Cyclic Peptide Amphiphile Containing Tryptophan and Arginine, Amir Nasrolahi Shirazi, Rakesh Kumar Tiwari, Donghoon Oh, Antara Banarjee, Arpita Yadav, and Keykavous Parang

PDF

Surface Decorated Gold Nanoparticles by Linear and Cyclic Peptides as Molecular Transporters, Amir Nasrolahi Shirazi, Rakesh Kumar Tiwari, Donghoon Oh, Brian Sullivan, Kellen McCaffrey, Dindyal Mandal, and Keykavous Parang

PDF

Mechanistic insights into isoform-dependent and species-specific regulation of bile salt export pump by farnesoid X receptor, Xiulong Song, Yuan Chen, Leila Valanejad, Rajani Kaimal, Bingfang Yan, Matthew Stoner, and Ruitang Deng

PDF

Short-term treatment with tolfenamic acid improves cognitive functions in Alzheimer's disease mice, Gehad M. Subaiea, Lina I. Adwan, Aseef H. Ahmed, Karen E. Stevens, and Nasser H. Zawia

PDF

Synthesis of novel ciprofloxacin analogues and evaluation of their anti-proliferative effect on human cancer cell lines, Narva Suresh, Hunsur Nagendra Nagesh, Kondapalli V. G. C. Sekhar, Anil Kumar, Amir N. Shirazi, and Keykavous Parang

PDF

Insights into the Conformation of Aminofluorene-Deoxyguanine Adduct in a DNA Polymerase Active Site, Vaidyanathan G. Vaidyanathan, Fengting Liang, William A. Beard, David D. Shock, Samuel H. Wilson, and Bongsup P. Cho

PDF

Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs, Da Xiao, Deshi Shi, Dongfang Yang, Benjamin Barthel, Tad H. Koch, and Bingfang Yan

PDF

Keap1-Knockdown Decreases Fasting-Induced Fatty Liver via Altered Lipid Metabolism and Decreased Fatty Acid Mobilization from Adipose Tissue, Jialin Xu, Ajay C. Donepudi, Jamie E. Moscovitz, and Angela Slitt

PDF

pHLIP peptide targets nanogold particles to tumors, Lan Yao, Jennifer Daniels, Anna Moshnikova, Sergey Kuznetsov, Aftab Ahmed, Donald M. Engelman, Yana Reshetnyak, and Oleg A. Andreev

PDF

ABCC3 as a marker for multidrug resistance in non-small cell lung cancer, Yanbin Zhao, Hailing Lu, An Yan, Yanmei Yang, Qingwei Meng, Lichun Sun, Hui Pang, Chunhong Li, Xiaoqun Dong, and Li Cai

Submissions from 2012

PDF

Synthesis and anti-HIV activities of symmetrical dicarboxylate esters of dinucleoside reverse transcriptase inhibitors, Hitesh K. Agarwal, Karen W. Buckheit, Robert W. Buckheit Jr., and Keykavous Parang

PDF

Integration of genome-wide expression and methylation data: Relevance to aging and Alzheimer's disease, Hany Alashwal, Remi Dosunmu, and Nasser H. Zawia

PDF

Anticancer activity and biophysical reactivity of copper complexes of 2-(benzo[d][1,3]dioxol-5-ylmethylene)-N-alkylhydrazinecarbothioamides, Floyd A. Beckford, Jeffrey Thessing, Alyssa Stott, Alvin A. Holder, Oleg G. Poluetov, Liya Li, and Navindra P. Seeram

PDF

Antioxidant sulforaphane and sensitizer trinitrobenzene sulfonate induce carboxylesterase-1 through a novel element transactivated by nuclear factor-E2 related factor-2, Yi-Tzai Chen, Deshi Shi, Dongfang Yang, and Bingfang Yan

PDF

N-Myristoylglutamic acid derivative of 3′-fluoro-3′-deoxythymidine as an organogel, Bhupender S. Chhikara, Rakesh Tiwari, and Keykavous Parang

PDF

Developmental exposure to lead (Pb) alters the expression of the human tau gene and its products in a transgenic animal model, M. Dash, A. Eid, G. Subaiea, J. Chang, R. Deeb, A. Masoud, William E. Renehan, A. Adem, and Nasser H. Zawia

PDF

Pharmacy Research at URI: Bile Acids and Bile Salt Export Pump: Physiology and Pathology, Ruitang Deng

PDF

Genome-wide expression and methylation profiling in the aged rodent brain due to early-life Pb exposure and its relevance to aging, Remi Dosunmu, Hany Alashwal, and Nasser H. Zawia

PDF

In vitro Transdermal Permeation of Fenoterol Hydrobromide, Ahmed H. Elshafeey, Yassin E. Hamza, Soad Y. Amin, and Hossein Zia

PDF

Antiamoebic properties of the actinomycete metabolites echinomycin A and tirandamycin A, Avelina Espinosa, Aaron M. Socha, Erica Ryke, and David C. Rowley

PDF

Going Deep for Drug Discovery: An Ocean to Bedside Approach to Explore Sub-Seafloor Microbes for the Next Generation of Antibiotics, Stephanie Forschner-Dancause, Kerry L. LaPlante, David C. Smith, and David C. Rowley

PDF

Strong Association Between Two Polymorphisms on 15q25.1 and Lung Cancer Risk: A Meta-Analysis, Mingliang Gu, Xiaoqun Dong, Xuezhi Zhang, Xumin Wang, Yue Qi, Jun Yu, and Wenquan Niu

PDF

Combination of TRAIL and actinomycin D liposomes enhances antitumor effect in non-small cell lung cancer, Liangran Guo, Li Fan, Jinfeng Ren, Zhiqing Pang, Yulong Ren, Jingwei Li, Ziyi Wen, Yong Qian, Lin Zhang, Hang Ma, and Xinguo Jiang

PDF

Synergistic Association of PTGS2 and CYP2E1 Genetic Polymorphisms with Lung Cancer Risk in Northeastern Chinese, Shujie Guo, Xiaobo Li, Min Gao, Hong Kong, Yuqiong Li, Mingliang Gu, Xiaoqun Dong, and Wenquan Niu

PDF

Unusual Sequence Effects on Nucleotide Excision Repair of Arylamine Lesions: DNA Bending/Distortion as a Primary Recognition Factor, Vipin Jain, Benjamin Hilton, Bin Lin, Satyakam Patnaik, Fengting Liang, Eva Darian, Yue Zou, Alexander D. MacKerell Jr., and Bongsup P. Cho

PDF

Conformational and Thermodynamic Properties Modulate the Nucleotide Excision Repair of 2-aminofluorene and 2-acetylaminofluorene dG adducts in the NarI Sequence, Vipin Jain, Benjamin Hilton, Satyakam Patnaik, Yue Zou, M. Paul Chiarelli, and Bongsup P. Cho

PDF

Association of the 5-HTT Gene-Linked Promoter Region (5-HTTLPR) Polymorphism with Psychiatric Disorders: Review of Psychopathology and Pharmacotherapy, George A. Kenna, Nick Roder-Hanna, Lorenzo Leggio, William H. Zywiak, James Clifford, Steven Edwards, John A. Kenna, Jessica Shoaff, and Robert M. Swift

PDF

Insulin Resistance, Ceramide Accumulation, and Endoplasmic Reticulum Stress in Human Chronic Alcohol-Related Liver Disease, Lisa Longato, Kelsey Ripp, Mashiko Setshedi, Miroslav Dostalek, Fatemeh Akhlaghi, Mark Branda, Jack R. Wands, and Suzanne M. de la Monte

PDF

Nanoparticles for Cancer Treatment, Wei Lu

PDF

DEC1 binding to the proximal promoter of CYP3A4 ascribes to the downregulation of CYP3A4 expression by IL-6 in primary human hepatocytes, Zhao Mao, Xiaofei Luan, Gang Cao, Wei Liu, Jing Xiong, Gang Hu, Ruini Chen, Rui Ning, Wei Shang, Jian Yang, and Bingfang Yan

PDF

Severe Diabetes and Leptin Resistance Cause Differential Hepatic and Renal Transporter Expression in Mice, Vijay More, Xia Wen, Paul E. Thomas, Lauren M. Aleksunes, and Angela L. Slitt

PDF

Quantitative Analysis of Some Important Metals and Metalloids in Tobacco Products by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS), Syed Ghulam Musharraf, Muhammad Shoaib, Amna Jabbar Siddiqui, Muhammad Najam-ul-Haq, and Aftab Ahmed

PDF

4-Aryl-4H-Naphthopyrans Derivatives: One-Pot Synthesis, Evaluation of Src Kinase Inhibitory and Anti-Proliferative Activities, Ali Rafinejad, Asal Fallah-Tafti, Rakesh Tiwari, Amir Nasrolahi Shirazi, Deendayal Mandal, Abbas Shafiee, Keykavous Parang, Alireza Foroumadi, and Tahmineh Akbarzadeh

PDF

One-pot regioselective synthesis of tetrahydroindazolones and evaluation of their antiproliferative and Src kinase inhibitory activities, V. Kameshwara Rao, Bhupender S. Chhikara, Rakesh Tiwari, Amir Nasrolahi Shirazi, Keykavous Parang, and Anil Kumar

PDF

Pharmacy Research at URI: Mining Red Maple (Acer rubrum) Trees for Novel Therapeutics to Manage Diabetes, Navindra P. Seeram, Jialin Xu, Liya Li, and Angela Slitt

PDF

Hepatic immunosuppressive effects of systemically administered novel dextran–methylprednisolone prodrugs with peptide linkers in rats, Imam H. Shaik, Hitesh K. Agarwal, Keykavous Parang, and Reza Mehvar

PDF

Community annotation and bioinformatics workforce development in concert—Little Skate Genome Annotation Workshops and Jamborees, Qinghua Wang, Cecilia N. Arighi, Benjamin L. King, Shawn W. Polson, James Vincent, Chumching Chen, Hongzhan Huang, Brewster F. Kingham, Shallee T. Page, Marc Farnum Rendino, William Kelley Thomas, Daniel W. Udwary, and Cathy H. Wu

PDF

Age-related inducibility of carboxylesterases by the antiepileptic agent phenobarbital and implications in drug metabolism and lipid accumulation, Da Xiao, Yi-Tzai Chen, Dongfang Yang, and Bingfang Yan

PDF

Enhanced Nrf2 Activity Worsens Insulin Resistance, Impairs Lipid Accumulation in Adipose Tissue, and Increases Hepatic Steatosis in Leptin-Deficient Mice, Jialin Xu, Supriya R. Kulkarni, Ajay C. Donepudi, Vijay R. More, and Angela L. Slitt

PDF

Hypolipidemic agent Z-guggulsterone: metabolism interplays with induction of carboxylesterase and bile salt export pump, Dongfang Yang, Jian Yang, Deshi Shi, Da Xiao, Yi-Tzai Chen, Chris Black, Ruitang Deng, and Bingfang Yan

Submissions from 2011

PDF

Synthesis and anti-HIV activities of bis-(cycloSaligenyl) pronucleotides derivatives of 3′-fluoro-3′-deoxythymidine and 3′-azido-3′-deoxythymidine, Yousef Ahmadibeni, Rakesh Tiwari, Chelsie Swepson, Jui Pandhare, Chandravanu Dash, Gustavo F. Doncel, and Keykavous Parang

PDF

Synthesis and characterization of mixed-ligand diimine-piperonal thiosemicarbazone complexes of ruthenium(II): Biophysical investigations and biological evaluation as anticancer and antibacterial agents, Floyd A. Beckford, Jeffrey Thessing, Michael Shaloski Jr., P. Canisius Mbarushimana, Alyssa Brock, Jacob Didion, Jason Woods, Antonio Gonzalez-Sarrías, and Navindra P. Seeram

PDF

Half-sandwich ruthenium–arene complexes with thiosemicarbazones: Synthesis and biological evaluation of [(η6-p-cymene)Ru(piperonal thiosemicarbazones)Cl]Cl complexes, Floyd Beckford, Deidra Dourth, Michael Shaloski Jr., Jacob Didion, Jeffrey Thessing, Jason Woods, Vernon Crowell, Nikolay Gerasimchuk, Antonio Gonzalez-Sarrías, and Navindra P. Seeram

PDF

Multicomponent folate-targeted magnetoliposomes: design, characterization, and cellular uptake, Geoffrey D. Bothun, Alline Lelis, Yanjing Chen, Kyle Scully, Linnea E. Anderson, and Matthew A. Stoner

PDF

Constitutive activation of nuclear factor‐E2‐related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte‐specific deletion of Kelch‐like ECH‐associated protein 1, Qiuqiong Cheng, Keiko Taguchi, Lauren M. Aleksunes, José E. Manautou, Nathan J. Cherrington, Masayuki Yamamoto, and Angela L. Slitt

PDF

Inhibition of multi-drug resistant HIV-1 reverse transcriptase by nucleoside β-triphosphates, Chandravanu Dash, Yousef Ahmadibeni, Michael J. Hanley, Jui Pandhare, Mathias Gotte, Stuart F.J. Le Grice, and Keykavous Parang

PDF

Substituted Coumarin Derivatives: Synthesis and Evaluation of Antiproliferative and Src Kinase Inhibitory Activities, Abha Kathuria, Sarah Jalal, Rakesh Tiwari, Amir Nasrolahi Shirazi, Shilpi Gupta, Shiv Kumar, Keykavous Parang, and Sunil K. Sharma

PDF

Synthesis of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates and evaluation of their Src kinase inhibitory and anticancer activities, Anil Kumar, Israr Ahmad, Bhupender S. Chhikara, Rakesh Tiwari, Deendayal Mandal, and Keykavous Parang

PDF

Click chemistry inspired one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles and their Src kinase inhibitory activity, Dalip Kumar, V. Buchi Reddy, Anil Kumar, Deendayal Mandal, Rakesh Tiwari, and Keykavous Parang

PDF

Harnessing the power of genomics and immunoinformatics to produce improved vaccines, Leonard Moise, Leslie Cousens, Joanna Fueyo, and Anne S. De Groot