Publications from the Department of Biomedical and Pharmaceutical Sciences faculty at the University of Rhode Island.

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Submissions from 2010

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Development of a population pharmacokinetic model for atorvastatin acid and its lactone metabolite, Rajesh Narwal, Fatemeh Akhlaghi, Anders Åsberg, Monica Hermann, and Sara E. Rosenbaum

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Intestinal permeability enhancement of levothyroxine sodium by straight chain fatty acids studied in MDCK epithelial cell line, Dimple Pabla, Fatemeh Akhlaghi, and Hossein Zia

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Structures of 2-acetylaminofluorene modified DNA revisited: Insight into conformational heterogeneity, Satyakam Patnaik and Bongsup P. Cho

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Plasma Pharmacokinetics and Tissue Disposition of Novel Dextran–Methylprednisolone Conjugates With Peptide Linkers in Rats, Suman Penugonda, Hitesh K. Agarwal, Keykavous Parang, and Reza Mehvar

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Dexamethasone transcriptionally increases the expression of the pregnane X receptor and synergistically enhances pyrethroid esfenvalerate in the induction of cytochrome P450 3A23, Deshi Shi, Dongfang Yang, and Bingfang Yan

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Pregnane X receptor is required for interleukin-6-mediated down-regulation of cytochrome P450 3A4 in human hepatocytes, Jian Yang, Chunshu Hao, Dongfang Yang, Deshi Shi, Xiulong Song, Xiaofei Luan, Gang Hu, and Bingfang Yan

Submissions from 2009

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Synthesis of Nucleoside Mono-, Di-, and Triphosphoramidates from Solid-Phase cycloSaligenyl Phosphitylating Reagents, Yousef Ahmadibeni, Rakesh K. Tiwari, Gongqin Sun, and Keykavous Parang

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Organometallic ruthenium complexes with thiosemicarbazone ligands: Synthesis, structure and cytotoxicity of [(η6-p-cymene)Ru(NS)Cl]+ (NS = 9-anthraldehyde thiosemicarbazones), Floyd A. Beckford, Gabriel Leblanc, Jeffrey Thessing, Michael Shaloski Jr., Brian J. Frost, Liya Li, and Navindra P. Seeram

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Food and food supplements with hypocholesterolemic effects, Ruitang Deng

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Development of a sensitive and selective method for the quantitative analysis of cortisol, cortisone, prednisolone and prednisone in human plasma, Ileana A. Ionita, Douglas M. Fast, and Fatemeh Akhlaghi

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Influence of Flanking Sequence Context on the Conformational Flexibility of Aminofluorene-Modified dG Adduct in dA Mismatch DNA Duplexes, Nidhi Jain, Srinivasarao Meneni, Vipin Jain, and Bongsup P. Cho

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Differential modulation of farnesoid X receptor signaling pathway by the thiazolidinediones, Rajani Kaimal, Xiulong Song, Bingfang Yan, Roberta King, and Ruitang Deng

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Eugenia jambolana Lam. Berry Extract Inhibits Growth and Induces Apoptosis of Human Breast Cancer but Not Non-Tumorigenic Breast Cells, Liya Li, Lynn S. Adams, Shiuan Chen, Caroline Killian, Aftab Ahmed, and Navindra P. Seeram

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A comparative pH-dissolution profile study of selected commercial levothyroxine products using inductively coupled plasma mass spectrometry, Dimple Pabla, Fatemeh Akhlaghi, and Hossein Zia

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Population pharmacokinetics of mycophenolic acid and its 2 glucuronidated metabolites in kidney transplant recipients, Wai Johnn Sam, Fatemeh Akhlaghi, and Sara E. Rosenbaum

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Secondary Metabolites Produced by the Marine Bacterium Halobacillus salinus That Inhibit Quorum Sensing-Controlled Phenotypes in Gram-Negative Bacteria, Margaret E. Teasdale, Jianyuan Liu, Joselynn Wallace, Fatemeh Akhlaghi, and David C. Rowley

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Human carboxylesterases HCE1 and HCE2: Ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin, Dongfang Yang, Robin e. Pearce, Xiliang Wang, Roger Gaedigk, Yu-Jui Yvonne Wan, and Bingfang Yan

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Pyrethroid insecticides: Isoform-dependent hydrolysis, induction of cytochrome P450 3A4 and evidence on the involvement of the pregnane X receptor, Dongfeng Yang, Xiliang Wang, Yi-tzai Chen, Ruitang Deng, and Bingfang Yan

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Synthesis and evaluation of phosphopeptides containing iminodiacetate groups as binding ligands of the Src SH2 domain, Guofeng Ye, Aaron D. Schuler, Yousef Ahmadibeni, Joel R. Morgan, Absar Faruqui, Kezhen Huang, Gongqin Sun, John A. Zebala, and Keykavous Parang

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Effect of guggulsterone and cembranoids of Commiphora mukul on pancreatic phospholipase A2: Role in hypocholesterolemia, Bao Zhu Yu, Rajani Kaimal, Shi Bai, Khalid A. El Sayed, Suren A. Tatulian, Rafael J. Apitz, Mahendra K. Jain, Ruitang Deng, and Otto G. Berg

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Epigenetics, oxidative stress, and Alzheimer disease, Nasser H. Zawia, Debomoy K. Lahiri, and Fernando Cardozo-Pelaez

Submissions from 2008

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An initial animal proof-of-concept study for central administration of clozapine to schizophrenia patients, Daniel J. Abrams, Lijun Zheng, Kevin S. Choo, Jun J. Yang, Wei Wei, Thomas J. Anchordoquy, Nasser H. Zawia, and Karen E. Stevens

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Development and validation of an HPLC-UV method for iodixanol quantification in human plasma, Shripad D. Chitnis and Fatemeh Akhlaghi

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Natural Products Chemistry and Taxonomy of the Marine Cyanobacterium Blennothrix cantharidosmum, Benjamin R. Clark, Niclas Engene, Margaret E. Teasdale, David C. Rowley, Teatulohi Matainaho, Frederick A. Valeriote, and William H. Gerwick

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Declining intracellular T-lymphocyte concentration of cyclosporine A precedes acute rejection in kidney transplant recipients, Pål Falck, Anders Åsberg, Heidi Guldseth, Sara Bremer, Fatemeh Akhlaghi, Jan L.E. Reubsaet, Per Pfeffer, Anders Hartmann, and Karsten Midtvedt

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Sequence Verification of Oligonucleotides Containing Multiple Arylamine Modifications by Enzymatic Digestion and Liquid Chromatography Mass Spectrometry (LC/MS), Lan Gao, Li Zhang, Bongsup P. Cho, and M. Paul Chiarelli

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Fluorescence Probing of Aminofluorene-Induced Conformational Heterogeneity in DNA Duplexes, Nidhi Jain, Yana K. Reshetnyak, Lan Gao, M. Paul Chiarelli, and Bongsup P. Cho

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In Vitro and In Vivo Evidence for Lack of Endovascular Remodeling by Third Trimester Trophoblasts, S. Kalkunte, Z. Lai, N. Tewari, Clinton O. Chichester III, R. Romero, J. Padbury, and S. Sharma

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α,β-Methylene-2′-deoxynucleoside 5′-triphosphates as noncleavable substrates for DNA polymerases: Isolation, characterization, and stability studies of novel 2′-deoxycyclonucleosides, 3,5′-cyclo-dG, and 2,5′-cyclo-dT, Fengting Liang, Nidhi Jain, Troy Hutchens, David D. Shock, William A. Beard, Samuel H. Wilson, M. Paul Chiarelli, and Bongsup P. Cho

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The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4α, Fu Jun Liu, Xiulong Song, Dongfang Yang, Ruitang Deng, and Bingfang Yan

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Rapid activation of ERK1/2 and AKT in human breast cancer cells by cadmium, Zhiwei Liu, Xinyuan Yu, and Zahir A. Shaikh

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Blood and plasma pharmacokinetics of ciclosporin in diabetic kidney transplant recipients, Anisha E. Mendonza, Reginald Y. Gohh, and Fatemeh Akhlaghi

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Development and validation of an inductively coupled plasma mass spectrometry method for quantification of levothyroxine in dissolution studies, Dimple Pabla, Fatemeh Akhlaghi, Aftab Ahmed, and Hossein Zia

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DEC1, a Basic Helix-Loop-Helix Transcription Factor and a Novel Target Gene of the p53 Family, Mediates p53-dependent Premature Senescence, Yingjuan Qian, Jin Zhang, Bingfang Yan, and Xinbin Chen

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Dexamethasone suppresses the expression of multiple rat carboxylesterases through transcriptional repression: Evidence for an involvement of the glucocorticoid receptor, Deshi Shi, Jian Yang, Dongfang Yang, and Bingfang Yan

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Liver receptor homolog 1 transcriptionally regulates human bile salt export pump expression, Xiulong Song, Rajani Kaimal, Bingfang Yan, and Ruitang Deng

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Alzheimer's Disease (AD)-Like Pathology in Aged Monkeys after Infantile Exposure to Environmental Metal Lead (Pb): Evidence for a Developmental Origin and Environmental Link for AD, Jinfang Wu, Md. Riyaz Basha, Brian Brock, David P. Cox, Fernando Cardozo-Pelaez, Christopher A. McPherson, Jean Harry, Deborah C. Rise, Brian Maloney, Demaio Chen, Debomoy K. Lahiri, and Nasser H. Zawia

Submissions from 2007

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Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event, Rasha Bhandari, Adolfo Saiardi, Yousef Ahmadibeni, Adele M. Snowman, Adam C. Resnick, Troels Z. Kristiansen, Henrik Molina, Akhilesh Pandey, J. Kent Werner Jr., Krishna R. Juluri, Yong Xu, Glenn D. Prestwich, Keykavous Parang, and Solomon H. Snyder

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Synthesis and antifungal properties of α-methoxy and α-hydroxyl substituted 4-thiatetradecanoic acids, Néstor M. Carballeira, Rosann O'Neill, and Keykavous Parang

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Therapeutic effects of guggul and its constituent guggulsterone: Cardiovascular benefits, Ruitang Deng

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The hypolipidemic agent guggulsterone regulates the expression of human bile salt export pump: Dominance of transactivation over farsenoid X receptor-mediated antagonism, Ruitang Deng, Dongfang Yang, Amy Radke, Jian Yang, and Bingfang Yan

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Probing the sequence effects on NarI-induced -2 frameshift mutagenesis by dynamic 19F NMR, UV, and CD spectroscopy, Nidhi Jain, Yuyuan Li, Li Zhang, Srinivasa R. Meneni, and Bongsup P. Cho

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Probing the thermodynamics of aminofluorene-induced translesion DNA synthesis by differential scanning calorimetry, Fengting Liang and Bongsup P. Cho

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Tacrolimus in diabetic kidney transplant recipients: Pharmacokinetics and application of a limited sampling strategy, Anisha E. Mendonza, Hamim Zahir, Reginald Y. Gohh, and Fatemeh Akhlaghi

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Examination of the Long-range Effects of Aminofluorene-induced Conformational Heterogeneity and Its Relevance to the Mechanism of Translesional DNA Synthesis, Srinivasarao Meneni, Fengting Liang, and Bongsup P. Cho

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Spectroscopic and theoretical insights into sequence effects of aminofluorene-induced conformational heterogeneity and nucleotide excision repair, Srinivasa Rao Meneni, Steven M. Shell, Lan Gao, Petr Jurecka, Wang Lee, Jiri Sponer, Yue Zou, M. Paul Chiarelli, and Bongsup P. Cho

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Conformation-specific recognition of carcinogen-DNA adduct in Escherichia coli nucleotide excision repair, Srinivasa Rao Meneni, Steven M. Shell, Yue Zou, and Bongsup P. Cho

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Concentrations of mycophenolic acid and glucuronide metabolites under concomitant therapy with cyclosporine or tacrolimus, Chirag G. Patel, Matthew Harmon, Reginald Y. Gohh, and Fatemeh Akhlaghi

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Effect of diabetes mellitus on mycophenolate sodium pharmacokinetics and inosine monophosphate dehydrogenase activity in stable kidney transplant recipients, Chirag G. Patel, Katherine Richman, Dongfang Yang, Bingfang Yan, Reginald Y. Gohh, and Fatemeh Akhlaghi

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Synthesis and in Vitro Characterization of Novel Dextran–Methylprednisolone Conjugates with Peptide Linkers: Effects of Linker Length on Hydrolytic and Enzymatic Release of Methylprednisolone and its Peptidyl Intermediates, Suman Penugonda, Anil Kumar, Hitesh K. Agarwal, Keykavous Parang, and Reza Mehvar

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Carboxyhemoglobin monitored by bedside continuous CO-oximetry, Troilus Plante, Darcy Harris, Julie Savitt, Fatemeh Akhlaghi, James Monti, and Gregory D. Jay

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Response to comments on "anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel" [3], Deshi Shi, Jian Yang, Dongfang Yang, Edward L. LeCluyse, Chris Black, Li You, Fatemeh Akhlaghi, and Bingfang Yang

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Synthesis and Evaluation of Tripodal Peptide Analogues for Cellular Delivery of Phosphopeptides, Guofeng Ye, Nguyen-Hai Nam, Anil Kumar, Ali Saleh, Dinesh B. Shenoy, Mansoor M. Amiji, Xiaofeng Lin, Gongqin Sun, and Keykavous Parang

Submissions from 2006

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Pharmacokinetics of mycophenolic acid and metabolites in diabetic kidney transplant recipients, Fatemeh Akhlaghi, Chirag G. Patel, X. Patricia Zuniga, Jenana Halilovic, Ido S. Preis, and Reginald Y. Gohh

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2,6‐hexadecadiynoic acid and 2,6‐nonadecadiynoic acid: Novel synthesized acetylenic fatty acids as potent antifungal agents, Néstor M. Carballeira, David Sanabria, Clarisa Cruz, Keykavous Parang, Baojie Wan, and Scott Franzblau

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Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor, Ruitang Deng, Dongfang Yang, Jian Yang, and Bingfang Yan

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Cooperation between MEF2 and PPARγ in Human Intestinal β,β-Carotene 15,15'-Monooxygenase Gene Expression, Xiaoming Gong, Shu-Whei Tsai, Bingfang Yan, and Lewis P. Rubin

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Synthesis of Polymer-Bound 4-Acetoxy-3-phenylbenzaldehyde Derivatives:  Applications in Solid-Phase Organic Synthesis, Anil Kumar, Guofeng Ye, Yousef Ahmadibeni, and Keykavous Parang

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Docking-based Substrate Recognition by the Catalytic Domain of a Protein Tyrosine Kinase, C-terminal Src Kinase (Csk), Sungsoo Lee, Marina K. Ayrapetov, David J. Kemble, Keykavous Parang, and Gongqin Sun

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Induced circular dichroism characteristics as conformational probes for carcinogenic aminofluorene-DNA adducts, Fengting Liang, Srinivasa Rao Meneni, and Bongsup P. Cho

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Product ion studies of diastereomeric benzo[ghi]fluoranthene-2′- deoxynucleoside adducts by electrospray ionization and quadrupole ion trap mass spectrometry, Linge Li, Hui-Fang Chang, Kenneth W. Olsen, Bongsup P. Cho, and M. Paul Chiarelli

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The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter, Y. Li, M. Xie, J. Yang, D. Yang, R. Deng, Y. Wan, and B. Yan

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Analysis of mycophenolic acid in saliva using liquid chromatography tandem mass spectrometry, Anisha E. Mendonza, Reginald Y. Gohh, and Fatemeh Akhlaghi

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Erratum: Sequence effects of aminofluorene-modified DNA duplexes: Thermodynamic and circular dichroism properties (Nucleic Acids Research (2006) vol. 34 (755-763)), Srinivasa Rao Meneni, Rhijuta D'Mello, Gregory Norigian, Gregory Baker, Lan Gao, M. Paul Chiarelli, and Bongsup P. Cho

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High-performance liquid chromatography method for the determination of mycophenolic acid and its acyl and phenol glucuronide metabolites in human plasma, Chirag G. Patel and Fatemeh Akhlaghi

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Sequence effects of aminofluorene-modified DNA duplexes: thermodynamic and circular dichroism properties, Srinivasa Rao Meneni, Rhijuta D'Mello, Gregory Norigian, Gregory Baker, Lin Gao, M. Paul Chiarelli, and Bongsup P. Cho

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Letter to the editor [2], Sara E. Rosenbaum and Fatemeh Akhlaghi

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Anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel, Deshi Shi, Jian Yang, Dongfang Yang, Edward L. LeCluyse, Chris Black, Li You, Fatemeh Akhlaghi, and Bingfang Yan

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Synthesis and characterization of enantiomeric anti-2-fluorobenzo[a]pyrene- 7,8-dihydrodiol-9,10-epoxides and their 2′-deoxyguanosine and oligodeoxynucleotide adducts, Tianle Yang, Yanhe Huang, and Bongsup P. Cho

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Apparent clearance of sirolimus in heart transplant recipients: Impact of primary diagnosis and serum lipids, Hamim Zahir, Anne M. Keogh, and Fatemeh Akhlaghi

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Erratum: Apparent clearance of sirolimus in heart transplant recipients: Impact of primary diagnosis and serum lipids (Therapeutic Drug Monitoring (2006) 28, 5 (614-622)), H. Zahir, A. M. Keogh, and F. Akhlaghi

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Inhibition of EGFR/PI3K/AKT cell survival pathway promotes TSA's effect on cell death and migration in human ovarian cancer cells, Changlin Zhou, Lihua Qiu, Yun Sun, Sarah Healey, Harold Wanebo, Nicola Kouttab, Wen Di, Bingfang Yan, and Yinsheng Wan

Submissions from 2005

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Association between cyclosporine concentrations at 2 hours post-dose and clinical outcomes in de novo lung transplant recipients, Fatemeh Akhlaghi, Liliana Gonzalez, and Andrew K. Trull

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1H NMR analysis of GHB and GBL: Further findings on the interconversion and a preliminary report on the analysis of GHB in serum and urine, Anthony G. Del Signore, Michael McGregor, and Bongsup P. Cho

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Plasma Clearance of Lovastatin Versus Chinese Red Yeast Rice in Healthy Volunteers, Zhaoping Li, Navindra P. Seeram, Rupo Lee, Gail Thames, Chayo Minutti, He-Jing Wang, and David Heber

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Antagonistic Interactions among Marine Bacteria Impede the Proliferation of Vibrio cholerae, Richard A. Long, David C. Rowley, Eric Zamora, Jiayuan Liu, Douglas H. Bartlett, and Farooq Azam

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The Fetal Basis of Amyloidogenesis: Exposure to Lead and Latent Overexpression of Amyloid Precursor Protein and β-Amyloid in the Aging Brain, M. Riyaz Basha, Wei Wei, Saleh A. Bakheet, Nathalie Benitez, Hasan K. Siddiqi, Yuan-Wen Ge, Debomoy K. Lahiri, and Nasser H. Zawia

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Population pharmacokinetics of cyclosporine in cardiopulmonary transplant recipients, Sara E. Rosenbaum, Gautam Baheti, Andrew K. Trull, and Fatemeh Akhlaghi

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Development and validation of an HPLC-UV method for determination of iohexol in human plasma, Rohit S. Soman, Hamim Zahir, and Fatemeh Akhlaghi

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Population pharmacokinetic estimation of tacrolimus apparent clearance in adult liver transplant recipients, Hamim Zahir, Andrew J. McLachlan, Ameeta Nelson, Geof McCaughan, Margaret Gleeson, and Fatemeh Akhlaghi

Submissions from 2004

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Erratum: Structural differentiation of diastereomeric benzo[ghi] fluoranthene adducts of deoxy-adenosine by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and postsource decay (Chemical Research in Toxicolgy (October 2003) 16, 10 (1236-1241)), M. Paul Chiarelli, Hui-Fang Chang, Kenneth W. Olsen, Damon Barbacci, Bongsup P. Cho, and Duane M. Huffer

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Dynamic conformational heterogeneities of carcinogen-DNA adducts and their mutagenic relevance, Bongsup P. Cho

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Inhibitors of Protein Kinase Signaling Pathways: Emerging Therapies for Cardiovascular Disease, Thomas Force, Keisuke Kuida, Mark Namchuk, Keykavous Parang, and John M. Kyriakis

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Determination of cyclosporine in saliva using liquid chromatography-tandem mass spectrometry, Anisha Mendonza, Reginald Gohh, and Fatemeh Akhlaghi

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Determination of total mycophenolic acid and its glucuronide metabolite using liquid chromatography with ultraviolet detection and unbound mycophenolic acid using tandem mass spectrometry, Chirag G. Patel, Anisha E. Mendonza, Fatemeh Akhlaghi, Oneeb Majid, Andrew K. Trull, Terry Lee, and David W. Holt

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Synthesis and spectroscopic characterization of some chromanochalcones and their dihydro derivatives, M. Srinivasa Rao, J. Kotesh, R. Narukulla, and H. Duddeck

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Immunosuppression, eotaxin and the diagnostic changes in eosinophils that precede early acute heart allograft rejection, Andrew K. Trull, Fatemeh Akhlaghi, Susan C. Charman, Sylvia Endenberg, Oneeb Majid, Jacqueline Cornelissen, Louise Steel, Jayan Parameshwar, John Wallwork, and Stephen Large

Submissions from 2003

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Structural Differentiation of Diastereomeric Benzo[ghi]fluoranthene Adducts of Deoxyadenosine by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and Postsource Decay, M. Paul Chiarelli, Hui-Fang Chang, Kenneth W. Olsen, Damon Barbacci, and Bongsup P. Cho

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Synthesis and characterization of N-demethylated metabolites of malachite green and leucomalachite green, Bongsup P. Cho, Tianle Yang, Lonnie R. Blankenship, Joanna D. Moody, Mona Churchwell, Frederick A. Beland, and Sandra J. Culp

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DEC1 Negatively Regulates the Expression of DEC2 through Binding to the E-box in the Proximal Promoter, Yuxin Li, Mingxing Xie, Xiulong Song, Sarah Gragen, Karuna Sachdeva, Yinsheng Wan, and Bingfang Yan

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Relationship between reproductive success and male plasma vitellogenin concentrations in cunner, Tautogolabrus adspersus, Lesley J. Mills, Ruth E. Gutjahr-Gobell, Doranne Borsay Horowitz, Nancy D. Denslow, Marjorie C. Chow, and Gerald E. Zaroogian

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Cyclosporin C2 and C0 concentration monitoring in stable, long-term heart transplant recipients receiving metabolic inhibitors, John E. Ray, Anne M. Keogh, Andrew J. McLachlan, and Fatemah Akhlaghi

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Preparation of diarylamines by the addition of 4-(N,N-dimethylamino)phenyllithium to nitroarenes, Tianle Yang and Bongsup P. Cho

Submissions from 2002

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Risk factors for the development and progression of dyslipidemia after heart transplantation, Fatemeh Akhlaghi, Christopher H. Jackson, Jayan Parameshwar, Linda D. Sharples, and Andrew K. Trull

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Distribution of cyclosporin in organ transplant recipients, Fatemeh Akhlaghi and Andrew K. Trull

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Characterization of DNA adducts derived from syn-benzo[ghi]fluoranthene- 3,4-dihydrodiol-5,5a-epoxide and comparative DNA binding studies with structurally-related anti-diolepoxides of benzo[ghi]fluoranthene and benzo[c]phenanthrene, Hui-Fang Chang, Duane M. Huffer, M. Paul Chiarelli, Lonnie R. Blankenship, Sandra J. Culp, and Bongsup P. Cho

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Characterization of DNA adducts and tetraols derived from anti-Benzo[ghi]fluoranthane-3,4-dihydrodiol-5,5a-epoxide, Hui-Fang Chang, Duane M. Huffer, M. Paul Chiarelli, and Bongsup P. Cho

Submissions from 2001

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Product ion studies of diastereomeric benzo[ghi]fluoranthene tetraols by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and post-source decay, Duane M. Huffer, Hui-Fang Fang Chang, Bongsup P. Cho, Li Kang Zhang, and M. Paul Chiarelli

Submissions from 2000

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Synthesis and characterization of 4'-amino and 4'-nitro derivatives of 4-N, N-dimethylaminotriphenylmethane as precursors for a proximate malachite green metabolite, Bongsup P. Cho, Lonnie R. Blankenship, Joanna D. Moody, Daniel R. Doerge, Frederick A. Beland, and Sandra J. Culp

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A Population Pharmacokinetic Analysis of Nelfinavir Mesylate in Human Immunodeficiency Virus-Infected Patients Enrolled in a Phase III Clinical Trial, Kimberly A. Jackson, Sara E. Rosenbaum, Bradley M. Kerr, Yazdi K. Pithavala, Geoffrey Yuen, and Michael N. Dudley