Submissions from 2010
Enthalpy - entropy contribution to carcinogen-induced DNA conformational heterogeneity, Fengting Liang and Bongsup P. Cho
Phenolics from Cornus amomum Mill. fruit, Hang Ma, Liya Li, and Navindra P. Seeram
Membrane Anchor R9AP Potentiates GTPase-accelerating Protein Activity of RGS11·Gβ5 Complex and Accelerates Inactivation of the mGluR6-G0 Signaling, Ikuro Masuho, Jeremy Celver, Abraham Kovoor, and Kirill A. Martemyanov
Development of a population pharmacokinetic model for atorvastatin acid and its lactone metabolite, Rajesh Narwal, Fatemeh Akhlaghi, Anders Åsberg, Monica Hermann, and Sara E. Rosenbaum
Intestinal permeability enhancement of levothyroxine sodium by straight chain fatty acids studied in MDCK epithelial cell line, Dimple Pabla, Fatemeh Akhlaghi, and Hossein Zia
Structures of 2-acetylaminofluorene modified DNA revisited: Insight into conformational heterogeneity, Satyakam Patnaik and Bongsup P. Cho
Plasma Pharmacokinetics and Tissue Disposition of Novel Dextran–Methylprednisolone Conjugates With Peptide Linkers in Rats, Suman Penugonda, Hitesh K. Agarwal, Keykavous Parang, and Reza Mehvar
Dexamethasone transcriptionally increases the expression of the pregnane X receptor and synergistically enhances pyrethroid esfenvalerate in the induction of cytochrome P450 3A23, Deshi Shi, Dongfang Yang, and Bingfang Yan
Pregnane X receptor is required for interleukin-6-mediated down-regulation of cytochrome P450 3A4 in human hepatocytes, Jian Yang, Chunshu Hao, Dongfang Yang, Deshi Shi, Xiulong Song, Xiaofei Luan, Gang Hu, and Bingfang Yan
Submissions from 2009
Synthesis of Nucleoside Mono-, Di-, and Triphosphoramidates from Solid-Phase cycloSaligenyl Phosphitylating Reagents, Yousef Ahmadibeni, Rakesh K. Tiwari, Gongqin Sun, and Keykavous Parang
Organometallic ruthenium complexes with thiosemicarbazone ligands: Synthesis, structure and cytotoxicity of [(η6-p-cymene)Ru(NS)Cl]+ (NS = 9-anthraldehyde thiosemicarbazones), Floyd A. Beckford, Gabriel Leblanc, Jeffrey Thessing, Michael Shaloski Jr., Brian J. Frost, Liya Li, and Navindra P. Seeram
Food and food supplements with hypocholesterolemic effects, Ruitang Deng
Development of a sensitive and selective method for the quantitative analysis of cortisol, cortisone, prednisolone and prednisone in human plasma, Ileana A. Ionita, Douglas M. Fast, and Fatemeh Akhlaghi
Influence of Flanking Sequence Context on the Conformational Flexibility of Aminofluorene-Modified dG Adduct in dA Mismatch DNA Duplexes, Nidhi Jain, Srinivasarao Meneni, Vipin Jain, and Bongsup P. Cho
Differential modulation of farnesoid X receptor signaling pathway by the thiazolidinediones, Rajani Kaimal, Xiulong Song, Bingfang Yan, Roberta King, and Ruitang Deng
Eugenia jambolana Lam. Berry Extract Inhibits Growth and Induces Apoptosis of Human Breast Cancer but Not Non-Tumorigenic Breast Cells, Liya Li, Lynn S. Adams, Shiuan Chen, Caroline Killian, Aftab Ahmed, and Navindra P. Seeram
A comparative pH-dissolution profile study of selected commercial levothyroxine products using inductively coupled plasma mass spectrometry, Dimple Pabla, Fatemeh Akhlaghi, and Hossein Zia
Population pharmacokinetics of mycophenolic acid and its 2 glucuronidated metabolites in kidney transplant recipients, Wai Johnn Sam, Fatemeh Akhlaghi, and Sara E. Rosenbaum
Secondary Metabolites Produced by the Marine Bacterium Halobacillus salinus That Inhibit Quorum Sensing-Controlled Phenotypes in Gram-Negative Bacteria, Margaret E. Teasdale, Jianyuan Liu, Joselynn Wallace, Fatemeh Akhlaghi, and David C. Rowley
Human carboxylesterases HCE1 and HCE2: Ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin, Dongfang Yang, Robin e. Pearce, Xiliang Wang, Roger Gaedigk, Yu-Jui Yvonne Wan, and Bingfang Yan
Pyrethroid insecticides: Isoform-dependent hydrolysis, induction of cytochrome P450 3A4 and evidence on the involvement of the pregnane X receptor, Dongfeng Yang, Xiliang Wang, Yi-tzai Chen, Ruitang Deng, and Bingfang Yan
Synthesis and evaluation of phosphopeptides containing iminodiacetate groups as binding ligands of the Src SH2 domain, Guofeng Ye, Aaron D. Schuler, Yousef Ahmadibeni, Joel R. Morgan, Absar Faruqui, Kezhen Huang, Gongqin Sun, John A. Zebala, and Keykavous Parang
Effect of guggulsterone and cembranoids of Commiphora mukul on pancreatic phospholipase A2: Role in hypocholesterolemia, Bao Zhu Yu, Rajani Kaimal, Shi Bai, Khalid A. El Sayed, Suren A. Tatulian, Rafael J. Apitz, Mahendra K. Jain, Ruitang Deng, and Otto G. Berg
Epigenetics, oxidative stress, and Alzheimer disease, Nasser H. Zawia, Debomoy K. Lahiri, and Fernando Cardozo-Pelaez
Submissions from 2008
An initial animal proof-of-concept study for central administration of clozapine to schizophrenia patients, Daniel J. Abrams, Lijun Zheng, Kevin S. Choo, Jun J. Yang, Wei Wei, Thomas J. Anchordoquy, Nasser H. Zawia, and Karen E. Stevens
Development and validation of an HPLC-UV method for iodixanol quantification in human plasma, Shripad D. Chitnis and Fatemeh Akhlaghi
Natural Products Chemistry and Taxonomy of the Marine Cyanobacterium Blennothrix cantharidosmum, Benjamin R. Clark, Niclas Engene, Margaret E. Teasdale, David C. Rowley, Teatulohi Matainaho, Frederick A. Valeriote, and William H. Gerwick
Declining intracellular T-lymphocyte concentration of cyclosporine A precedes acute rejection in kidney transplant recipients, Pål Falck, Anders Åsberg, Heidi Guldseth, Sara Bremer, Fatemeh Akhlaghi, Jan L.E. Reubsaet, Per Pfeffer, Anders Hartmann, and Karsten Midtvedt
Sequence Verification of Oligonucleotides Containing Multiple Arylamine Modifications by Enzymatic Digestion and Liquid Chromatography Mass Spectrometry (LC/MS), Lan Gao, Li Zhang, Bongsup P. Cho, and M. Paul Chiarelli
Fluorescence Probing of Aminofluorene-Induced Conformational Heterogeneity in DNA Duplexes, Nidhi Jain, Yana K. Reshetnyak, Lan Gao, M. Paul Chiarelli, and Bongsup P. Cho
In Vitro and In Vivo Evidence for Lack of Endovascular Remodeling by Third Trimester Trophoblasts, S. Kalkunte, Z. Lai, N. Tewari, Clinton O. Chichester III, R. Romero, J. Padbury, and S. Sharma
α,β-Methylene-2′-deoxynucleoside 5′-triphosphates as noncleavable substrates for DNA polymerases: Isolation, characterization, and stability studies of novel 2′-deoxycyclonucleosides, 3,5′-cyclo-dG, and 2,5′-cyclo-dT, Fengting Liang, Nidhi Jain, Troy Hutchens, David D. Shock, William A. Beard, Samuel H. Wilson, M. Paul Chiarelli, and Bongsup P. Cho
The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4α, Fu Jun Liu, Xiulong Song, Dongfang Yang, Ruitang Deng, and Bingfang Yan
Rapid activation of ERK1/2 and AKT in human breast cancer cells by cadmium, Zhiwei Liu, Xinyuan Yu, and Zahir A. Shaikh
Blood and plasma pharmacokinetics of ciclosporin in diabetic kidney transplant recipients, Anisha E. Mendonza, Reginald Y. Gohh, and Fatemeh Akhlaghi
Development and validation of an inductively coupled plasma mass spectrometry method for quantification of levothyroxine in dissolution studies, Dimple Pabla, Fatemeh Akhlaghi, Aftab Ahmed, and Hossein Zia
DEC1, a Basic Helix-Loop-Helix Transcription Factor and a Novel Target Gene of the p53 Family, Mediates p53-dependent Premature Senescence, Yingjuan Qian, Jin Zhang, Bingfang Yan, and Xinbin Chen
Dexamethasone suppresses the expression of multiple rat carboxylesterases through transcriptional repression: Evidence for an involvement of the glucocorticoid receptor, Deshi Shi, Jian Yang, Dongfang Yang, and Bingfang Yan
Liver receptor homolog 1 transcriptionally regulates human bile salt export pump expression, Xiulong Song, Rajani Kaimal, Bingfang Yan, and Ruitang Deng
Alzheimer's Disease (AD)-Like Pathology in Aged Monkeys after Infantile Exposure to Environmental Metal Lead (Pb): Evidence for a Developmental Origin and Environmental Link for AD, Jinfang Wu, Md. Riyaz Basha, Brian Brock, David P. Cox, Fernando Cardozo-Pelaez, Christopher A. McPherson, Jean Harry, Deborah C. Rise, Brian Maloney, Demaio Chen, Debomoy K. Lahiri, and Nasser H. Zawia
Submissions from 2007
Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event, Rasha Bhandari, Adolfo Saiardi, Yousef Ahmadibeni, Adele M. Snowman, Adam C. Resnick, Troels Z. Kristiansen, Henrik Molina, Akhilesh Pandey, J. Kent Werner Jr., Krishna R. Juluri, Yong Xu, Glenn D. Prestwich, Keykavous Parang, and Solomon H. Snyder
Synthesis and antifungal properties of α-methoxy and α-hydroxyl substituted 4-thiatetradecanoic acids, Néstor M. Carballeira, Rosann O'Neill, and Keykavous Parang
Therapeutic effects of guggul and its constituent guggulsterone: Cardiovascular benefits, Ruitang Deng
The hypolipidemic agent guggulsterone regulates the expression of human bile salt export pump: Dominance of transactivation over farsenoid X receptor-mediated antagonism, Ruitang Deng, Dongfang Yang, Amy Radke, Jian Yang, and Bingfang Yan
Probing the sequence effects on NarI-induced -2 frameshift mutagenesis by dynamic 19F NMR, UV, and CD spectroscopy, Nidhi Jain, Yuyuan Li, Li Zhang, Srinivasa R. Meneni, and Bongsup P. Cho
Probing the thermodynamics of aminofluorene-induced translesion DNA synthesis by differential scanning calorimetry, Fengting Liang and Bongsup P. Cho
Tacrolimus in diabetic kidney transplant recipients: Pharmacokinetics and application of a limited sampling strategy, Anisha E. Mendonza, Hamim Zahir, Reginald Y. Gohh, and Fatemeh Akhlaghi
Examination of the Long-range Effects of Aminofluorene-induced Conformational Heterogeneity and Its Relevance to the Mechanism of Translesional DNA Synthesis, Srinivasarao Meneni, Fengting Liang, and Bongsup P. Cho
Spectroscopic and theoretical insights into sequence effects of aminofluorene-induced conformational heterogeneity and nucleotide excision repair, Srinivasa Rao Meneni, Steven M. Shell, Lan Gao, Petr Jurecka, Wang Lee, Jiri Sponer, Yue Zou, M. Paul Chiarelli, and Bongsup P. Cho
Conformation-specific recognition of carcinogen-DNA adduct in Escherichia coli nucleotide excision repair, Srinivasa Rao Meneni, Steven M. Shell, Yue Zou, and Bongsup P. Cho
Concentrations of mycophenolic acid and glucuronide metabolites under concomitant therapy with cyclosporine or tacrolimus, Chirag G. Patel, Matthew Harmon, Reginald Y. Gohh, and Fatemeh Akhlaghi
Effect of diabetes mellitus on mycophenolate sodium pharmacokinetics and inosine monophosphate dehydrogenase activity in stable kidney transplant recipients, Chirag G. Patel, Katherine Richman, Dongfang Yang, Bingfang Yan, Reginald Y. Gohh, and Fatemeh Akhlaghi
Synthesis and in Vitro Characterization of Novel Dextran–Methylprednisolone Conjugates with Peptide Linkers: Effects of Linker Length on Hydrolytic and Enzymatic Release of Methylprednisolone and its Peptidyl Intermediates, Suman Penugonda, Anil Kumar, Hitesh K. Agarwal, Keykavous Parang, and Reza Mehvar
Carboxyhemoglobin monitored by bedside continuous CO-oximetry, Troilus Plante, Darcy Harris, Julie Savitt, Fatemeh Akhlaghi, James Monti, and Gregory D. Jay
Response to comments on "anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel" [3], Deshi Shi, Jian Yang, Dongfang Yang, Edward L. LeCluyse, Chris Black, Li You, Fatemeh Akhlaghi, and Bingfang Yang
Synthesis and Evaluation of Tripodal Peptide Analogues for Cellular Delivery of Phosphopeptides, Guofeng Ye, Nguyen-Hai Nam, Anil Kumar, Ali Saleh, Dinesh B. Shenoy, Mansoor M. Amiji, Xiaofeng Lin, Gongqin Sun, and Keykavous Parang
Submissions from 2006
Pharmacokinetics of mycophenolic acid and metabolites in diabetic kidney transplant recipients, Fatemeh Akhlaghi, Chirag G. Patel, X. Patricia Zuniga, Jenana Halilovic, Ido S. Preis, and Reginald Y. Gohh
2,6‐hexadecadiynoic acid and 2,6‐nonadecadiynoic acid: Novel synthesized acetylenic fatty acids as potent antifungal agents, Néstor M. Carballeira, David Sanabria, Clarisa Cruz, Keykavous Parang, Baojie Wan, and Scott Franzblau
Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor, Ruitang Deng, Dongfang Yang, Jian Yang, and Bingfang Yan
Cooperation between MEF2 and PPARγ in Human Intestinal β,β-Carotene 15,15'-Monooxygenase Gene Expression, Xiaoming Gong, Shu-Whei Tsai, Bingfang Yan, and Lewis P. Rubin
Synthesis of Polymer-Bound 4-Acetoxy-3-phenylbenzaldehyde Derivatives: Applications in Solid-Phase Organic Synthesis, Anil Kumar, Guofeng Ye, Yousef Ahmadibeni, and Keykavous Parang
Docking-based Substrate Recognition by the Catalytic Domain of a Protein Tyrosine Kinase, C-terminal Src Kinase (Csk), Sungsoo Lee, Marina K. Ayrapetov, David J. Kemble, Keykavous Parang, and Gongqin Sun
Induced circular dichroism characteristics as conformational probes for carcinogenic aminofluorene-DNA adducts, Fengting Liang, Srinivasa Rao Meneni, and Bongsup P. Cho
Product ion studies of diastereomeric benzo[ghi]fluoranthene-2′- deoxynucleoside adducts by electrospray ionization and quadrupole ion trap mass spectrometry, Linge Li, Hui-Fang Chang, Kenneth W. Olsen, Bongsup P. Cho, and M. Paul Chiarelli
The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter, Y. Li, M. Xie, J. Yang, D. Yang, R. Deng, Y. Wan, and B. Yan
Analysis of mycophenolic acid in saliva using liquid chromatography tandem mass spectrometry, Anisha E. Mendonza, Reginald Y. Gohh, and Fatemeh Akhlaghi
Erratum: Sequence effects of aminofluorene-modified DNA duplexes: Thermodynamic and circular dichroism properties (Nucleic Acids Research (2006) vol. 34 (755-763)), Srinivasa Rao Meneni, Rhijuta D'Mello, Gregory Norigian, Gregory Baker, Lan Gao, M. Paul Chiarelli, and Bongsup P. Cho
High-performance liquid chromatography method for the determination of mycophenolic acid and its acyl and phenol glucuronide metabolites in human plasma, Chirag G. Patel and Fatemeh Akhlaghi
Sequence effects of aminofluorene-modified DNA duplexes: thermodynamic and circular dichroism properties, Srinivasa Rao Meneni, Rhijuta D'Mello, Gregory Norigian, Gregory Baker, Lin Gao, M. Paul Chiarelli, and Bongsup P. Cho
Letter to the editor [2], Sara E. Rosenbaum and Fatemeh Akhlaghi
Anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel, Deshi Shi, Jian Yang, Dongfang Yang, Edward L. LeCluyse, Chris Black, Li You, Fatemeh Akhlaghi, and Bingfang Yan
Synthesis and characterization of enantiomeric anti-2-fluorobenzo[a]pyrene- 7,8-dihydrodiol-9,10-epoxides and their 2′-deoxyguanosine and oligodeoxynucleotide adducts, Tianle Yang, Yanhe Huang, and Bongsup P. Cho
Apparent clearance of sirolimus in heart transplant recipients: Impact of primary diagnosis and serum lipids, Hamim Zahir, Anne M. Keogh, and Fatemeh Akhlaghi
Erratum: Apparent clearance of sirolimus in heart transplant recipients: Impact of primary diagnosis and serum lipids (Therapeutic Drug Monitoring (2006) 28, 5 (614-622)), H. Zahir, A. M. Keogh, and F. Akhlaghi
Inhibition of EGFR/PI3K/AKT cell survival pathway promotes TSA's effect on cell death and migration in human ovarian cancer cells, Changlin Zhou, Lihua Qiu, Yun Sun, Sarah Healey, Harold Wanebo, Nicola Kouttab, Wen Di, Bingfang Yan, and Yinsheng Wan
Submissions from 2005
Association between cyclosporine concentrations at 2 hours post-dose and clinical outcomes in de novo lung transplant recipients, Fatemeh Akhlaghi, Liliana Gonzalez, and Andrew K. Trull
1H NMR analysis of GHB and GBL: Further findings on the interconversion and a preliminary report on the analysis of GHB in serum and urine, Anthony G. Del Signore, Michael McGregor, and Bongsup P. Cho
Plasma Clearance of Lovastatin Versus Chinese Red Yeast Rice in Healthy Volunteers, Zhaoping Li, Navindra P. Seeram, Rupo Lee, Gail Thames, Chayo Minutti, He-Jing Wang, and David Heber
Antagonistic Interactions among Marine Bacteria Impede the Proliferation of Vibrio cholerae, Richard A. Long, David C. Rowley, Eric Zamora, Jiayuan Liu, Douglas H. Bartlett, and Farooq Azam
The Fetal Basis of Amyloidogenesis: Exposure to Lead and Latent Overexpression of Amyloid Precursor Protein and β-Amyloid in the Aging Brain, M. Riyaz Basha, Wei Wei, Saleh A. Bakheet, Nathalie Benitez, Hasan K. Siddiqi, Yuan-Wen Ge, Debomoy K. Lahiri, and Nasser H. Zawia
Population pharmacokinetics of cyclosporine in cardiopulmonary transplant recipients, Sara E. Rosenbaum, Gautam Baheti, Andrew K. Trull, and Fatemeh Akhlaghi
Development and validation of an HPLC-UV method for determination of iohexol in human plasma, Rohit S. Soman, Hamim Zahir, and Fatemeh Akhlaghi
Population pharmacokinetic estimation of tacrolimus apparent clearance in adult liver transplant recipients, Hamim Zahir, Andrew J. McLachlan, Ameeta Nelson, Geof McCaughan, Margaret Gleeson, and Fatemeh Akhlaghi
Submissions from 2004
Erratum: Structural differentiation of diastereomeric benzo[ghi] fluoranthene adducts of deoxy-adenosine by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and postsource decay (Chemical Research in Toxicolgy (October 2003) 16, 10 (1236-1241)), M. Paul Chiarelli, Hui-Fang Chang, Kenneth W. Olsen, Damon Barbacci, Bongsup P. Cho, and Duane M. Huffer
Dynamic conformational heterogeneities of carcinogen-DNA adducts and their mutagenic relevance, Bongsup P. Cho
Inhibitors of Protein Kinase Signaling Pathways: Emerging Therapies for Cardiovascular Disease, Thomas Force, Keisuke Kuida, Mark Namchuk, Keykavous Parang, and John M. Kyriakis
Determination of cyclosporine in saliva using liquid chromatography-tandem mass spectrometry, Anisha Mendonza, Reginald Gohh, and Fatemeh Akhlaghi
Determination of total mycophenolic acid and its glucuronide metabolite using liquid chromatography with ultraviolet detection and unbound mycophenolic acid using tandem mass spectrometry, Chirag G. Patel, Anisha E. Mendonza, Fatemeh Akhlaghi, Oneeb Majid, Andrew K. Trull, Terry Lee, and David W. Holt
Synthesis and spectroscopic characterization of some chromanochalcones and their dihydro derivatives, M. Srinivasa Rao, J. Kotesh, R. Narukulla, and H. Duddeck
Immunosuppression, eotaxin and the diagnostic changes in eosinophils that precede early acute heart allograft rejection, Andrew K. Trull, Fatemeh Akhlaghi, Susan C. Charman, Sylvia Endenberg, Oneeb Majid, Jacqueline Cornelissen, Louise Steel, Jayan Parameshwar, John Wallwork, and Stephen Large
Submissions from 2003
Structural Differentiation of Diastereomeric Benzo[ghi]fluoranthene Adducts of Deoxyadenosine by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and Postsource Decay, M. Paul Chiarelli, Hui-Fang Chang, Kenneth W. Olsen, Damon Barbacci, and Bongsup P. Cho
Synthesis and characterization of N-demethylated metabolites of malachite green and leucomalachite green, Bongsup P. Cho, Tianle Yang, Lonnie R. Blankenship, Joanna D. Moody, Mona Churchwell, Frederick A. Beland, and Sandra J. Culp
DEC1 Negatively Regulates the Expression of DEC2 through Binding to the E-box in the Proximal Promoter, Yuxin Li, Mingxing Xie, Xiulong Song, Sarah Gragen, Karuna Sachdeva, Yinsheng Wan, and Bingfang Yan
Relationship between reproductive success and male plasma vitellogenin concentrations in cunner, Tautogolabrus adspersus, Lesley J. Mills, Ruth E. Gutjahr-Gobell, Doranne Borsay Horowitz, Nancy D. Denslow, Marjorie C. Chow, and Gerald E. Zaroogian
Cyclosporin C2 and C0 concentration monitoring in stable, long-term heart transplant recipients receiving metabolic inhibitors, John E. Ray, Anne M. Keogh, Andrew J. McLachlan, and Fatemah Akhlaghi
Preparation of diarylamines by the addition of 4-(N,N-dimethylamino)phenyllithium to nitroarenes, Tianle Yang and Bongsup P. Cho
Submissions from 2002
Risk factors for the development and progression of dyslipidemia after heart transplantation, Fatemeh Akhlaghi, Christopher H. Jackson, Jayan Parameshwar, Linda D. Sharples, and Andrew K. Trull
Distribution of cyclosporin in organ transplant recipients, Fatemeh Akhlaghi and Andrew K. Trull
Characterization of DNA adducts derived from syn-benzo[ghi]fluoranthene- 3,4-dihydrodiol-5,5a-epoxide and comparative DNA binding studies with structurally-related anti-diolepoxides of benzo[ghi]fluoranthene and benzo[c]phenanthrene, Hui-Fang Chang, Duane M. Huffer, M. Paul Chiarelli, Lonnie R. Blankenship, Sandra J. Culp, and Bongsup P. Cho
Characterization of DNA adducts and tetraols derived from anti-Benzo[ghi]fluoranthane-3,4-dihydrodiol-5,5a-epoxide, Hui-Fang Chang, Duane M. Huffer, M. Paul Chiarelli, and Bongsup P. Cho