Barringtogenol c-type triterpenoid saponins from the stem bark of Norway maple (acer platanoides)

Authors

Wen Xu, Northeastern University
Lu Zhang, University of Rhode Island
Raed Omar, College of Pharmacy
Wei Liu, Northeastern University
Zhengxi Wei, University of Rhode Island
Zengguang Zhang, Northeastern University
Yu Mu, Northeastern University
Navindra P. Seeram, University of Rhode Island
Xueshi Huang, Northeastern University
Hang Ma, University of Rhode Island
Liya Li, Northeastern University

Document Type

Article

Date of Original Version

1-1-2020

Abstract

Four new barringtogenol C-type triterpenoid saponins, namely acerplatanosides AâŠ-âŠD (1-4), along with 22 known compounds (5-26), were isolated from the stem bark of Norway maple (Acer platanoides). Their structures were elucidated on the basis of comprehensive spectroscopic analyses and chemical hydrolysis. This is the first report of triterpenoid saponins isolated from Norway maple. Compounds 1, 3, and 4 showed cytotoxicity against 4 human cancer cell lines with IC 50 values ranging from 9.4 to 39.5 μM.

Publication Title, e.g., Journal

Planta Medica

Volume

86

Issue

1

Citation/Publisher Attribution

Xu, Wen, Lu Zhang, Raed Omar, Wei Liu, Zhengxi Wei, Zengguang Zhang, Yu Mu, Navindra P. Seeram, Xueshi Huang, Hang Ma, and Liya Li. "Barringtogenol c-type triterpenoid saponins from the stem bark of Norway maple (acer platanoides)." Planta Medica 86, 1 (2020): 70-77. doi: 10.1055/a-1031-7283.