Publications from the Department of Biomedical and Pharmaceutical Sciences faculty at the University of Rhode Island.

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Submissions from 2022

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Safety and Tolerability of APOE Genotyping and Disclosure in Cognitively Normal Volunteers From the Butler Alzheimer’s Prevention Registry, Jessica Alber, Dominique Popescu, Louisa I. Thompson, Gina Marie Tonini, Edmund Arthur, Hwamee Oh, Stephen Correia, Stephen P. Salloway, and Athene K. Lee

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Mitochondrial and metabolic dysfunction in ageing and age-related diseases, João A. Amorim, Giuseppe Coppotelli, Anabela P. Rolo, Carlos M. Palmeira, Jaime M. Ross, and David A. Sinclair

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The Use of Simulation Based Learning: With Bachelor of Science Pharmaceutical Science and PharmD Students, Justin L. Gold, Amanda M. Chichester, and Clinton O. Chichester

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Mechanisms of Cannabidiol (CBD) in Cancer Treatment: A Review, Camren G. Heider, Sasha A. Itenberg, Jiajia Rao, Hang Ma, and Xian Wu

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Analysis of botanicals and botanical supplements by LC-MS/MS-based molecular networking: Approaches for annotating plant metabolites and authentication, Terra Marie M. Jouaneh, Neil Motta, Christine Wu, Cole Coffey, Christopher W. Via, Riley D. Kirk, and Matthew Bertin

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A Neuropsychological Perspective on Defining Cognitive Impairment in the Clinical Study of Alzheimer's Disease: Towards a More Continuous Approach, Roos J. Jutten, Louisa Thompson, Sietske A.M. Sikkes, Paul Maruff, José Luis Molinuevo, Henrik Zetterberg, Jessica Alber, David Faust, Serge Gauthier, Michael Gold, John Harrison, Athene K.W. Lee, and Peter J. Snyder

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Screening the PRISM Library against Staphylococcus aureus Reveals a Sesquiterpene Lactone from Liriodendron tulipifera with Inhibitory Activity, Riley D. Kirk, Margaret E. Rosario, Nana Oblie, Terra Marie M. Jouaneh, Marina A. Carro, Christine Wu, Andrew M. Kim, Elizabeth Leibovitz, Elizabeth Sage Hunter, Robert Literman, Sara M. Handy, David C. Rowley, and Matthew J. Bertin

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Magnetoelectric Polymer Membrane-Based Electrical Microenvironment with Magnetically Controlled Antibacterial Activity, Shanshan Lai, Yanjiao Wang, Yuanyuan Wan, Hang Ma, Liming Fang, and Jianyu Su

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Dietary polyphenol oleuropein and its metabolite hydroxytyrosol are moderate skin permeable elastase and collagenase inhibitors with synergistic cellular antioxidant effects in human skin fibroblasts, Huifang Li, Hao He, Chang Liu, Toyosi Akanji, Justin Gutkowski, Ruilian Li, Huiqun Ma, Yinsheng Wan, Panpan Wu, Dongli Li, Navindra P. Seeram, and Hang Ma

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Characterization of molecular interactions between cannabidiol and human plasma proteins (serum albumin and γ-globulin) by surface plasmon resonance, microcalorimetry, and molecular docking, Chang Liu, Ang Cai, Hui-Fang Li, Ni Deng, Bongsup P. Cho, Navindra P. Seeram, and Hang Ma

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New Monoterpene Acid and Gallic Acid Glucose Esters with Anti-Inflammatory Activity from Blue Gum (Eucalyptus globulus) Leaves, Wei Liu, Minglei Li, Guihua Wang, Hang Ma, Yu Mu, Dan Zheng, Xueshi Huang, and Liya Li

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Physical radiofrequency adjuvant enhances immune responses to influenza H5N1 vaccination, Zhuofan Li, Ki Hye Kim, Noopur Bhatnagar, Bo Ryoung Park, Subbiah Jeeva, Yu Jin Jung, Jannatul Raha, Sang Moo Kang, and Xinyuan Chen

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Biodegradable and Inherently Fluorescent pH-Responsive Nanoparticles for Cancer Drug Delivery, Kalindu Perera, Dat X. Nguyen, Dingbowen Wang, Aneetta E. Kuriakose, Jian Yang, Kytai T. Nguyen, and Jyothi U. Menon

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Inhibitory Effects of Cannabinoids on Acetylcholinesterase and Butyrylcholinesterase Enzyme Activities, Tess Puopolo, Chang Liu, Hang Ma, and Navindra P. Seeram

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A Decade of Time Series Sampling Reveals Thermal Variation and Shifts in Pseudo-nitzschia Species Composition That Contribute to Harmful Algal Blooms in an Eastern US Estuary, Katherine M. Roche, Alexa R. Sterling, Tatiana A. Rynearson, Matthew J. Bertin, and Bethany D. Jenkins

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Anti-inflammatory Activities of Cranberry Fruit Extracts in Human THP-1 Monocytes are Influenced by Their Phytochemical Composition, Liang Xue, Chang Liu, Hang Ma, Navindra P. Seeram, and Catherine C. Neto

Submissions from 2021

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The relationship between cerebral and retinal microbleeds in cerebral amyloid angiopathy (CAA): A pilot study, Jessica Alber, Edmund Arthur, Danielle Goldfarb, Jonathan Drake, Jerrold L. Boxerman, Brian Silver, Brian R. Ott, Lenworth N. Johnson, and Peter J. Snyder

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OCTA reveals remodeling of the peripheral capillary free zones in normal aging, Edmund Arthur, Jessica Alber, Louisa I. Thompson, Stuart Sinoff, and Peter J. Snyder

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Current State of Breast Cancer Diagnosis, Treatment, and Theranostics, Arya Bhushan, Andrea Gonsalves, and Jyothi Menon

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Identification of a Bacteria-produced Benzisoxazole with Antibiotic Activity against Multi-drug Resistant Acinetobacter baumannii, Robert W. Deering, Kristen E. Whalen, Ivan Alvarez, Kathryn Daffinee, Maya Beganovic, Kerry L. LaPlante, Shreya Kishore, Sijing Zhao, Brent Cezairliyan, Shen Yu, Margaret Rosario, Tracy J. Mincer, and David C. Rowley

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Treprostinil reduces mitochondrial injury during rat renal ischemia-reperfusion injury, Meiwen Ding, Evelyn Tolbert, Mark Birkenbach, Reginald Gohh, Fatemeh Akhlaghi, and Nisanne S. Ghonem

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Neuroendocrine Response to Exogenous Ghrelin Administration, Combined With Alcohol, in Heavy-Drinking Individuals: Findings From a Randomized, Double-Blind, Placebo-Controlled Human Laboratory Study, Mehdi Farokhnia, Kelly M. Abshire, Aaron Hammer, Sara L. Deschaine, Anitha Saravanakumar, Enoch Cobbina, Zhi-Bing You, Carolina L. Haass-Koffler, Mary R. Lee, Fatemeh Akhlaghi, and Lorenzo Leggio

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Anti-Parallel β-Hairpin Structure in Soluble Aβ Oligomers of Aβ40-Dutch and Aβ40-Iowa, Ziao Fu, William Van Nostrand, and Steven O. Smith

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Emerging drug delivery strategies for idiopathic pulmonary fibrosis treatment, Moez Ghumman, Dinesh Dhamecha, Andrea Gonsalves, Lauren Fortier, Parand Sorkhdini, Yang Zhou, and Jyothi U. Menon

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Synthesis and characterization of a novel pH-responsive drug-releasing nanocomposite hydrogel for skin cancer therapy and wound healing, Andrea Gonsalves, Pranjali Tambe, Duong Le, Dheeraj Thakore, Aniket S. Wadajkar, Jian Yang, Kytai T. Nguyen, and Jyothi U. Menon

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Pomegranate (Punica granatum) extract and its polyphenols reduce the formation of methylglyoxal-DNA adducts and protect human keratinocytes against methylglyoxal-induced oxidative stress, Hao Guo, Chang Liu, Qi Tang, Deyu Li, Yinsheng Wan, Jiu-Hong Li, Xing-Hua Gao, Navindra P. Seeram, Hang Ma, and Hong-Duo Chen

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Sarcoplasmic reticulum-mitochondria communication; implications for cardiac arrhythmia, Shanna Hamilton, Radmila Terentyeva, Richard T. Clements, Andriy E. Belevych, and Dmitry Terentyev

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MCU overexpression evokes disparate dose-dependent effects on mito-ROS and spontaneous Ca2 þ release in hypertrophic rat cardiomyocytes, Shanna Hamilton, Radmila Terentyeva, Fruzsina Perger, Benjamín Hernández Orengo, Benjamin Martin, Matthew W. Gorr, Andriy E. Belevych, Richard T. Clements, Sandor Gyorke, and Dmitry Terentyev

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Synthesis and biological evaluations of oleanolic acid indole derivatives as hyaluronidase inhibitors with enhanced skin permeability, Hao He, Huifang Li, Toyosi Akanji, Shengli Niu, Zhujun Luo, Dongli Li, Navindra P. Seeram, Panpan Wu, and Hang Ma

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Fenamates as Potential Therapeutics for Neurodegenerative Disorders, Jaunetta Hill and Nasser H. Zawia

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Isoform-Specific Effects of Apolipoprotein E on Markers of Inflammation and Toxicity in Brain Glia and Neuronal Cells In Vitro, Jaclyn Iannucci, Abhik Sen, and Paula Grammas

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Compounds from Mucuna pruriens Seeds and their Neuroprotective Effects, Shelby L. Johnson, Yu Lu, Hang Ma, Navindra P. Seeram, and Tao Yuan

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Celosiadines A and B, unusual guanidine alkaloids from Iresine diffusa, Caroline Killian, Shelby L. Johnson, Hang Ma, Brendan McKeown, Luke McDougall, Robert Hurta, Yongqiang Liu, and Navindra P. Seeram

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New Micropeptins with Anti-Neuroinflammatory Activity Isolated from a Cyanobacterial Bloom, Riley D. Kirk, Haiyin He, Paul G. Wahome, ShiBiao Wu, Guy T. Carter, and Matthew Bertin

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Inhibitory Effects and Surface Plasmon Resonance-Based Binding Affinities of Dietary Hydrolyzable Tannins and Their Gut Microbial Metabolites on SARS-CoV-2 Main Protease, Hui-Fang Li, Feng Xu, Chang Liu, Ang Cai, Joel A. Dain, Dongli Li, Navindra P. Seeram, Bongsup P. Cho, and Hang Ma

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Cannabidiol Protects Human Skin Keratinocytes from Hydrogen-Peroxide-Induced Oxidative Stress via Modulation of the Caspase-1-IL-1β Axis, Chang Liu, Huifang Li, Feng Xu, Xian Jiang, Hang Ma, and Navindra P. Seeram

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Small molecule inhibitors against PD-1/PD-L1 immune checkpoints and current methodologies for their development: a review, Chang Liu, Navindra P. Seeram, and Hang Ma

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Potentiation of Recombinant NP and M1-Induced Cellular Immune Responses and Protection by Physical Radiofrequency Adjuvant, Yibo Li, Zhoufan Li, Yiwen Zhao, and Xinyuan Chen

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Chemical Characterization and Hepatoprotective Effects of a Standardized Triterpenoid-Enriched Guava Leaf Extract, Yuanyuan Li, Jialin Xu, Dongli Li, Hang Ma, Yu Mu, Dan Zheng, Xueshi Huang, and Liya Li

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Vaccine delivery alerts innate immune systems for more immunogenic vaccination, Zhoufan Li, Yan Cao, Yibo Li, Yiwen Zhao, and Xinyuan Chen

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Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity, Zhoufan Li, Yiwen Zhao, Yibo Li, and Xinyuan Chen

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A Network Pharmacology Approach to Identify Potential Molecular Targets for Cannabidiol's Anti-Inflammatory Activity, Hang Ma, Feng Xu, Chang Liu, and Navindra P. Seeram

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Draft Genome Sequence of Salegentibacter sp. Strain BDJ18, a Plankton-Associated Bacterium in the Northeast Atlantic Ocean, Elizabeth J. McDermith, Alexa R. Sterling, Matthew J. Bertin, and Bethany D. Jenkins

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Feasibility study for detection of retinal amyloid in clinical trials: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial, Jennifer Ngolab, Michael Donohue, Alison Belsha, Jennifer Salazar, Paula Cohen, Sandhya Jaiswal, Veasna Tan, Devon Gessert, Shaina Korouri, Neelum T. Aggarwal, Jessica Alber, Ken Johnson, Gregory Jicha, Christopher van Dyck, James Lah, Stephen Salloway, Reisa A. Sperling, Paul S. Aisen, Michael S. Rafii, and Robert A. Rissman

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Hepatoprotective and anti-inflammatory effects of a standardized pomegranate (Punica granatum) fruit extract in high fat diet-induced obese C57BL/6 mice, Marisa Pfohl, Nicholas A. DaSilva, Emily Marques, Juliana Agudelo, Chang Liu, Michael Goedken, Angela L. Slitt, Navindra P. Seeram, and Hang Ma

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Sequence Dependent Repair of 1,N6-Ethenoadenine by DNA Repair Enzymes ALKBH2, ALKBH3, and AlkB, Rui Qi, Ke Bian, Fangyi Chen, Qi Tang, Xianhao Zhou, and Deyu Li

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Magnetic hydroxyapatite nanomaterial–cyclodextrin tethered polymer hybrids as anticancer drug carriers, Sivaraj Ramasamy, Dinesh Dhamecha, Kiruthiga Kaliyamoorthi, Archana Sumohan Pillai, Aleyamma Alexander, Premnath Dhanaraj, Jyothi U. Menon, and Israel V. Muthu Vijayan Enoch

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Draft Genome Sequence of Pseudoalteromonas sp. Strain JC3, Margaret E. Rosario, Jacqueline Camm, Damian Cavanagh, David C. Rowley, and David R. Nelson

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Anti-neuroinflammatory effects of a food-grade phenolic-enriched maple syrup extract in a mouse model of Alzheimer’s disease, Kenneth N. Rose, Benjamin J. Barlock, Nicholas A. DaSilva, Shelby L. Johnson, Chang Liu, Hang Ma, Robert Nelson, Fatemeh Akhlaghi, and Navindra P. Seeram

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Advances in Lipid-Based Nanoparticles for Cancer Chemoimmunotherapy, Tianqi Wang, Yusuke Suite, Saradha Miriyala, Jordan Dean, Nikos Tapinos, and Jie Shen

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Nanoparticle-stabilized encapsulation of borneol and citral: Physicochemical characteristics, storage stability, and enhanced antibacterial activities, Wen Wang, Zhihui Ren, Li Wang, Ying Cai, Hang Ma, Liming Fang, and Jianyu Su

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Oleanolic acid indole derivatives as novel α-glucosidase inhibitors: Synthesis, biological evaluation, and mechanistic analysis, Panpan Wu, Hao He, Hang Ma, Borong Tu, Jiahao Li, Shengzhu Guo, Silin Chen, Nana Cao, Wende Zheng, Xiaowen Tang, Dongli Li, Xuetao Xu, Xi Zheng, Zhaojun Sheng, Weiqian David Hong, and Kun Zhang

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Chemical characterization, antiproliferative and antifungal activities of Clinacanthus nutans, Wen Xu, Jiaying Li, Dongli Li, Junfeng Tan, Hang Ma, Yu Mu, Yan Wen, Lishe Gan, Xueshi Huang, and Liya Li

Submissions from 2020

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Estimation of self-sustained activity produced by persistent inward currents using firing rate profiles of multiple motor units in humans, Babak Afsharipour, Nagib Manzur, Jennifer Duchcherer, Keith K. Fenrich, Christopher K. Thompson, Francesco Negro, Katharina A. Quinlan, David J. Bennett, and Monica A. Gorassini

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A recommended “minimum data set” framework for SD-OCT retinal image acquisition and analysis from the Atlas of Retinal Imaging in Alzheimer’s Study (ARIAS), Jessica Alber, Edmund Arthur, Stuart Sinoff, Delia Cabrera DeBuc, Emily Y. Chew, Lori Douquette, Wendy V. Hatch, Chris Hudson, Amir Kashani, Cecelia S. Lee, Stephen Montaquila, Sima Mozdbar, Leonardo Provetti Cunha, Faryan Tayyari, Gregory Van Stavern, and Peter J. Snyder

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Developing retinal biomarkers for the earliest stages of Alzheimer's disease: What we know, what we don't, and how to move forward, Jessica Alber, Danielle Goldfarb, Louisa I. Thompson, Edmund Arthur, Kimberly Hernandez, Derrick Cheng, Delia Cabrera DeBuc, Francesca Cordeiro, Leonardo Provetti-Cunha, Jurre den Haan, Gregory P. Van Stavern, Stephen P. Salloway, Stuart Sinoff, and Peter J. Snyder

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Disruption of cholinergic neurotransmission, within a cognitive challenge paradigm, is indicative of Aβ-related cognitive impairment in preclinical Alzheimer’s disease after a 27-month delay interval, Jessica Alber, Paul Maruff, Claudia Y. Santos, Brian R. Ott, Stephen P. Salloway, Don C. Yoo, Richard B. Noto, Louisa I. Thompson, Danielle Goldfarb, Edmund Arthur, Alex Song, and Peter J. Snyder

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Saudiarabicains A-E, bioactive 19-acetoxyingol diterpenoids from Euphorbia saudiarabica, Abdullatif Bin Muhsinah, Alfarius Eko Nugroho, Huifang Li, Sarah Lazzaro, Nicholas A. DaSilva, Dongli Li, Hang Ma, Abdulrhman Alsayari, Hiroshi Morita, Yongqiang Liu, and Navindra P. Seeram

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The Coarse-Grained Plaque: A Divergent Aβ Plaque-Type in Early-Onset Alzheimer’s Disease, Baayla D. C. Boon, Marjolein Bulk, Allert J. Jonker, Tjado H. J. Morrema, Emma van den Berg, Marko Popovic, Jochen Walter, Sathish Kumar, Sven J. van der Lee, Henne Holstege, Xiaoyue Zhu, William E. Van Nostrand, Remco Natté, Louise van der Weerd, Femke H. Bouwman, Wilma D. J. van de Berg, Annemieke J. M. Rozemuller, and Jeroen J. M. Hoozemans

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Porous Polymeric Microspheres With Controllable Pore Diameters for Tissue Engineered Lung Tumor Model Development, Dinesh Dhamecha, Duong Le, Rachel Movsas, Andrea Gonsalves, and Jyothi Menon

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Anti-amebic effects of Chinese rhubarb (Rheum palmatum) leaves' extract, the anthraquinone rhein and related compounds, Avelina Espinosa, Guillermo Paz y Mino C, Yoly Santos, Hang Ma, Michael Nadeau, Navindra P. Seeram, and D C. Rowley

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Ginnalin A Inhibits Aggregation, Reverses Fibrillogenesis, and Alleviates Cytotoxicity of Amyloid β(1-42), Qi Fan, Yonglan Liu, Xiaoying Wang, Zhuang Zhang, Yaru Fu, Luyao Liu, Pengcheng Wang, Hongmin Ma, Hang Ma, Navindra P. Seeram, Jie Zheng, and Feimeng Zhou

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Short-term Treatment with Dabigatran Alters Protein Expression Patterns in a Late-Stage Tau-Based Alzheimer's Disease Mouse Model, Jaclyn Iannucci, Shelby L. Johnson, Mark Majchrzak, Benjamin J. Barlock, Fatemeh Akhlaghi, Navindra P. Seeram, Abhik Sen, and Paula Grammas

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High Glucose and Hypoxia-Mediated Damage to Human Brain Microvessel Endothelial Cells Induces an Altered, Pro-Inflammatory Phenotype in BV-2 Microglia In Vitro, Jaclyn Iannucci, Haripriya Vittal Rao, and Paula Grammas

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Thrombin, a Mediator of Coagulation, Inflammation, and Neurotoxicity at the Neurovascular Interface: Implications for Alzheimer’s Disease, Jaclyn Iannucci, William Renehan, and Paula Grammas

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Equol, a Blood–Brain Barrier Permeable Gut Microbial Metabolite of Dietary Isoflavone Daidzein, Exhibits Neuroprotective Effects against Neurotoxins Induced Toxicity in Human Neuroblastoma SH-SY5Y Cells and Caenorhabditis elegans, Shelby L. Johnson, Hyun Y. Park, Dhiraj A. Vattem, Paula Grammas, Hang Ma, and Navindra P. Seeram

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Laser facilitates week-long sustained transdermal drug delivery at high doses, Prateek Kakar, Zhuofan Li, Yibo Li, Yan Cao, and Xinyuan Chen

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Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System, Sunil Kounda, Rena Elkin, Saad Nadeem, Yuechuan Xue, Stefan Constantinou, Simon Sanggaard, Xiaodan Liu, Brittany Monte, Feng Xu, William Van Nostrand, Maiken Nedergaard, Hedok Lee, Joanna Wardlaw, Helene Benveniste, and Allen Tannenbaum

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Ultrasound-Enhanced Chemiluminescence for Bioimaging, Duong Le, Danesh Dhamecha, Andrea Gonsalves, and Jyothi Menon

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Jasmine (Jasminum grandiflorum) Flower Extracts Ameliorate Tetradecanoylphorbol Acetate Induced Ear Edema in Mice, Dongli Li, Xiaodan Tang, Chang Liu, Huifang Li, Shuzhen Li, Shili Sun, Xi Zheng, Panpan Wu, Xuetao Xu, Kun Zhang, and Hang Ma

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Thymocid®, a Standardized Black Cumin (Nigella sativa) Seed Extract, Modulates Collagen Cross-Linking, Collagenase and Elastase Activities, and Melanogenesis in Murine B16F10 Melanoma Cells, Huifang Li, Nicholas A. DaSilva, Weixie Liu, Jialin Xu, George W. Dombi, Joel A. Dain, Dongli Li, Jean Christopher Chambeu, Navindra P. Seeram, and Hang Ma

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Glucitol-core containing gallotannins-enriched red maple (Acer rubrum) leaves extract alleviated obesity via modulating short-chain fatty acid production in high-fat diet-fed mice, Liya Li, Hang Ma, Tingting Liu, Zhanjun Ding, Wei Lu, Qiong Gu, Yu Mu, Jun Xu, Navindra P. Seeram, Xueshi Huang, and Jialin Xu

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Cytoprotective effects of a proprietary red maple leaf extract and its major polyphenol, ginnalin A, against hydrogen peroxide and methylglyoxal induced oxidative stress in human keratinocytes, Chang Liu, Hao Guo, Joel A. A. Dain, Yinsheng Wan, Xing Hua Gao, Hong Duo Chen, Navindra P. Seeram, and Hang Ma

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Inhibitory Effect of Cannabidiol on the Activation of NLRP3 Inflammasome Is Associated with Its Modulation of the P2X7 Receptor in Human Monocytes, Chang Liu, Hang Ma, Angela L. Slitt, and Navindra P. Seeram

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Inhibitory Effects of Skin Permeable Glucitol-core Containing Gallotannins from Red Maple Leaves on Elastase and their Protective Effects on Human Keratinocytes, Chang Liu, Yiming Xu, Riley D. Kirk, Huifang Li, Dongli Li, Nicholas A. DaSilva, Matthew Bertin, Navindra P. Seeram, and Hang Ma

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Guavinoside B from: Psidium guajava alleviates acetaminophen-induced liver injury via regulating the Nrf2 and JNK signaling pathways, Yuanyuan Li, Jialin Xu, Dongli Li, Hang Ma, Yu Mu, Xueshi Huang, and Liya Li

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Endurance exercise training in pulmonary hypertension increases skeletal muscle electron transport chain supercomplex assembly, Danielle J. McCullough, Nouaying Kue, Thomas Mancini, Alexander Vang, Richard T. Clements, and Gaurav Choudhary

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Isolation of Isotrichophycin C and Trichophycins G–I from a Collection of Trichodesmium thiebautii, Kelly M. McManus, Riley D. Kirk, Christopher W. Via, James S. Lotti, Alexandre F. Roduit, Roberta Teta, Silvia Scarpato, Alfonso Magoni, and Matthew Bertin

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Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation, Joshua Owen, Eloise Thomas, Jyothi Menon, Michael Gray, Irini Skaripa-Koukelli, Martin R. Gill, Sheena Wallington, Rebecca L. Miller, Katherine Vallis, and Robert Carlisle

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Thermo-responsive Fluorescent Nanoparticles for Multimodal Imaging and Treatment of Cancers, Nikhil Pandey, Jyothi Menon, Masaya Takahashi, Jer-Tsong Hsieh, Jian Yang, Kytai T. Nguyen, and Aniket S. Wadajkar

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Longitudinal Cognitive Decline in a Novel Rodent Model of Cerebral Amyloid Angiopathy Type-1, Dominique L. Popescu, William Van Nostrand, and John K. Robinson

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Histological-based stainings using free-floating tissue sections, Emily M. Potts, Giuseppe Coppotelli, and Jaime M. Ross

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Environmental Enrichment: Disentangling the Influence of Novelty, Social, and Physical Activity on Cerebral Amyloid Angiopathy in a Transgenic Mouse Model, Lisa S. Robison, Nikita Francis, Dominique L. Popescu, Maria E. Anderson, Joshua Hatfield, Feng Xu, Brenda J. Anderson, William Van Nostrand, and John K. Robinson

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Phenolic-enriched maple syrup extract protects human keratinocytes against hydrogen peroxide and methylglyoxal induced cytotoxicity, Jie Sheng, Chang Liu, Sophia Petrovas, Yinsheng Wan, Hong Duo Chen, Navindra P. Seeram, and Hang Ma

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Retinal Imaging in Alzheimer's and Neurodegenerative Diseases, Peter J. Snyder, Jessica Alber, Clemens Alt, Lisa J. Bain, Brett E. Bouma, Femke H. Bouwman, Delia Cabrera DeBuc, Melanie C.W. Campbell, Maria C. Carrillo, Emily Y. Chew, M. Francesca Cordeiro, Michael R. Dueñas, Brian M. Fernández, Maya Koronyo-Hamaoui, Chiara La Morgia, Roxana O’Carare, Srinivas R. Sadda, Peter van Wijngaarden, and Heather M. Snyder

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Altered Motoneuron Properties Contribute to Motor Deficits in a Rabbit Hypoxia-Ischemia Model of Cerebral Palsy, Preston R. Steele, Clarissa Fantin Cavarsan, Lisa Dowaliby, Megan Westefeld, Natallia Katenka, Alexander Drobyshevsky, Monica A. Gorassini, and Katharina A. Quinlan

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Barringtogenol c-type triterpenoid saponins from the stem bark of Norway maple (acer platanoides), Wen Xu, Lu Zhang, Raed Omar, Wei Liu, Zhengxi Wei, Zengguang Zhang, Yu Mu, Navindra P. Seeram, Xueshi Huang, Hang Ma, and Liya Li

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Dysregulation of bile acids increases the risk for preterm birth in pregnant women, Sangmin You, Ai-Min Cui, Syed F. Hashmi, Xinmu Zhang, Christina Nadolny, Yuan Chen, Qiwen Chen, Xin Bush, Zachary Hurd, Winifer Ali, Gang Qin, and Ruitang Deng

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Improving immunogenicity and safety of flagellin as vaccine carrier by high-density display on virus-like particle surface, Yiwen Zhao, Zhuofan Li, Xiaoyue Zhu, Yan Cao, and Xinyuan Chen

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Robust neuroinflammation and perivascular pathology in rTg-DI rats, a novel model of microvascular cerebral amyloid angiopathy, Xiaoyue Zhu, Joshua Hatfield, Joseph K. Sullivan, Feng Xu, and William Van Nostrand

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Reduced Levels of Cerebrospinal Fluid/Plasma Aβ40 as an Early Biomarker for Cerebral Amyloid Angiopathy in RTg-DI Rats, Xiaoyue Zhu, Feng Xu, Michael D. Hoos, Hedok Lee, Helene Benveniste, and William Van Nostrand

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Copper Accumulation and the Effect of Chelation Treatment on Cerebral Amyloid Angiopathy Compared to Parenchymal Amyloid Plaques, Xiayoue Zhu, Tiffany W. Victor, Ashwin Ambi, Joseph K. Sullivan, Joshua Hatfield, Feng Xu, Lisa M. Miller, and William E. Van Nostrand

Submissions from 2019

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White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities, Jessica Alber and et al

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Biological Evaluation of DNA Biomarkers in a Chemically Defined and Site-Specific Manner, Ke Bian, James C. Delaney, Xianhao Zhou, and Deyu Li

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DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro, Ke Bian, Stefan AP Lenz, Qi Tang, Fangyi Chen, Rui Qi, Marco Jost, Catherine L. Drennan, John M. Essigmann, Stacey D. Wetmore, and Deyu Li

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Synthesis and tyrosinase inhibitory activities of 4-oxobutanoate derivatives of carvacrol and thymol, Nicholas Brotzman, Yiming Xu, Allison Graybill, Alexander Cocolas, Andrew Ressler, Navindra P. Seeram, Hang Ma, and Geneive E. Henry

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Probing the Effect of Bulky Lesion-Induced Replication Fork Conformational Heterogeneity Using 4-Aminobiphenyl-Modified DNA, Ang Cai, Ke Bian, Fangyi Chen, Qi Tang, Rachel Carley, Deyu Li, and Bongsup P. Cho

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Hydrolyzable Tannins Are Iron Chelators That Inhibit DNA Repair Enzyme ALKBH2, Fangyi Chen, Qi Tang, Hang Ma, Ke Bian, Navindra P. Seeram, and Deyu Li

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Downregulating NF-κB signaling pathway with triterpenoids for attenuating inflammation:: In vitro and in vivo studies, Min Chen, Ying Qin, Hang Ma, Xi Zheng, Renping Zhou, Shili Sun, Yiqi Huang, Qing Duan, Wenfeng Liu, Panpan Wu, Xuetao Xu, Zhaojun Sheng, Kun Zhang, and Dongli Li

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Pomegranate ellagitannin-gut microbial-derived metabolites, urolithins, inhibit neuroinflammation in vitro, Nicholas A. DaSilva, Pragati P. Nahar, Hang Ma, Aseel Eid, Zhengxi Wei, Susan Meschwitz, Nasser H. Zawia, Angela L. Slitt, and Navindra P. Seeram