Explore scholarly publications from the Department of Pharmacy Practice and Clinical Research faculty at the University of Rhode Island.

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Submissions from 2004

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Nonadherence as a predictor of antidiabetic drug therapy intensification (augmentation), Stephen J. Kogut, E. Andrade, Cynthia Willey, and E. Paul Larrat

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Daptomycin - A novel antibiotic against Gram-positive pathogens, Kerry L. LaPlante and J. Rybak

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Desmethoxyyangonin and dihydromethysticin are two major pharmacologigal kavalactones with marked activity on the induction of CYP3A23, Yuzhong Ma, Sachdeva, Jirong Liu, Michael Ford, Dongfang Yang, Ikhlas A. Khan, Clinton O. Chichester, and Bingfang Yan

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Principles for modeling propensity scores in medical research: A systematic literature review, Sherry Weitzen, L. Lapane, Alicia Y. Toledano, Anne L. Hume, and Vincent Mor

Submissions from 2003

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Metabolic syndrome and antipsychotic therapy: A summary of the findings, Robert L. Dufresne

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Detection of collagen type II and proteoglycans in the synovial fluids of patients diagnosed with non-infectious knee joint synovitis indicates early damage to the articular cartilage matrix, K. A. Elsaid, D. Jay, and C. O. Chichester

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Lumiracoxib: A COX-2 inhibitor for the treatment of arthritis and acute pain, Brett Feret and A. Quercia

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Curricula development, Anne L. Hume

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Herbal medicinal education, Anne L. Hume

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The natural product education exchange, Anne L. Hume

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Tooth discoloration after treatment with linezolid, Kelly L. Matson and E. Miller

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Lipopolysaccharide and cecal ligation/puncture differentially affect the subcellular distribution of the pregnane X receptor but consistently cause suppression of its target genes CYP3A, Karuna Sachdeva, Yan, and Clinton O. Chichester

Submissions from 2002

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Sulfation of indoxyl by human and rat aryl (phenol) sulfotransferases to form indoxyl sulfate, E. Banoglu and S. King

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Inpatient Antipsychotic Drug Use in 1998, 1993, and 1989, Franca Centorrino, Eakin, Won-Myong Bahk, James P. Kelleher, Jessica L. Gören, Paola Salvatore, Samy Egli, and Ross J. Baldessarini

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Use of potentially inappropriate drugs in nursing homes, Jyotsna Dhall, Paul Larrat, and Kate L. Lapane

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Does aspirin attenuate the effect of angiotensin-converting enzyme inhibitors on health outcomes of very old patients with heart failure?, Kate L. Lapane, L. Hume, Marilyn M. Barbour, and Lewis A. Lipsitz

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Drug product expiration dates: practice implications., Celia P. MacDonnell and A. Campbell

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Endotoxic shock alters the pharmacokinetics of lidocaine and monoethylglycinexylidide, David S. McKindley, Boulet, Karuna Sachdeva, Ping Wang, and Clinton Chichester

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Health Correlates of Exercise Behavior and Stage Change in a Community-Based Exercise Intervention for the Elderly: A Pilot Study, Claudio Nigg, English, Norma Owens, Patricia Burbank, Annie Connolly-Belanger, Robert Dufresne, Nancy Fey-Yensan, Carol Ewing Garber, Andrea Luisi, Cynthia Padula, Sandra Saunders, and Phillip Clark

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Developing and using interdisciplinary case studies in teaching geriatrics to practicing health care professionals, Norma J. Owens, A. Padula, and Anne L. Hume

Submissions from 2001

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Hepatic microsomal metabolism of indole to indoxyl, a precursor of indoxyl sulfate, Erden Banoglu, G. Jha, and Roberta S. King

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Pharmacology and pharmacotherapy of cardiovascular drugs in patients with chronic renal disease, Marilyn M. Barbour and S. McKindley

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Drug therapy and prevalence of erectile dysfunction in the Massachusetts male aging study cohort, Carol A. Derby, M. Barbour, Anne L. Hume, and John B. McKinlay

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Fondaparinux: A novel synthetic antithrombotic for prevention of venous thromboembolism, B. Feret

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Pharmacologic treatment of diabetes in long-term care, Joshua J. Spooner, L. Lapane, Anne L. Hume, Vincent Mor, and Giovanni Gambassi

Submissions from 2000

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Hormone replacement therapy should not be used as secondary prevention of coronary heart disease, M. M. Barbour

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Patient compliance and blood pressure control on a nuclear-powered aircraft carrier: Impact of a pharmacy officer, Mark E. Brouker, Gallagher, E. Paul Larrat, and Robert L. Dufresne

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Structure-function modeling of the interactions of N-alkyl-N-hydroxyanilines with rat hepatic aryl sulfotransferase IV, Roberta S. King, Sharma, Lars C. Pedersen, Yoshimitsu Kakuta, Masahiko Negishi, and Michael W. Duffel

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In vitro bioactivation of N-hydroxy-2-amino-α-carboline, Roberta S. King, H. Teitel, and Fred F. Kadlubar

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The Effect of Plan Characteristics on the Cost of Pharmaceuticals in a Private Third-Party Prescription Program, Soyal R. Momin, P. Lipson, E. Paul Larrat, James J. Brehany, and Rita M. Marcoux

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Oxidative and nonoxidative benzodiazepines and the risk of femur fracture, Antonio Sgadari, L. Lapane, Vincent Mor, Francesco Landi, Roberto Bernabei, Giovanni Gambassi, C. Gatsonis, L. Lipsitz, J. Hiris, C. Brostrup-Jensen, S. Gonzales, J. Hogan, O. Intrator, M. Barbour, K. Berg, E. Broderick, D. Forman, D. Gifford, A. Hume, P. Larratt, and K. Steel

Submissions from 1999

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Type II collagen peptide release from rabbit articular cartilage, B. R. Felice, O. Chichester, and H. J. Barrach

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Clozapine-associated elevation in serum triglycerides, Bruce D. Gaulin, S. Markowitz, Charles F. Caley, Lori A. Nesbitt, and Robert L. Dufresne

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Elevated serum triglycerides with clozapine resolved with risperidone in four patients, Padideh Ghaeli and L. Dufresne

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Antiischemic therapy in patients with coronary heart disease living in long-term care, Kate L. Lapane, M. Barbour, Anne Van Haaren, and Giovanni Gambassi

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Effect of endotoxin shock on the clearance of lidocaine and indocyanine green in the perfused rat liver, David S. McKindley, Chichester, and Richard Raymond

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Antihypertensive therapy in the elderly: Evidence-based guidelines and reality [1] (multiple letters), F. H. Messerli, Grodzicki, Z. Feng, G. Gambassi, K. Lapane, A. L. Hume, P. Carbonin, and R. Bernabei

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Olanzapine increases weight and serum triglyceride levels, David N. Osser, M. Najarian, and Robert L. Dufresne

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Articular collagen degradation in the Hulth-Telhag model of osteoarthritis, J. N. Rogart, J. Barrach, and C. O. Chichester

Submissions from 1998

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Prevalence, clinical correlates, and treatment of hypertension in elderly nursing home residents, Giovanni Gambassi, Lapane, Antonio Sgadari, Francesco Landi, Pierugo Carbonin, Anne Hume, Lewis Lipsitz, Vincent Mor, and Roberto Bernabei

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Thrombolysis in acute ischemic stroke (multiple letters), P. Hicks, L. Hume, and A. Luisi

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Thrombolysis in acute ischemic stroke, Anne L. Hume

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Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow, Alastair M. Mackay, C. Beck, J. Mary Murphy, Frank P. Barry, Clinton O. Chichester, and Mark F. Pittenger

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Current knowledge of the cytochrome P-450 isozyme system: can we predict clinically important drug interactions?, D. S. McKindley and L. Dufresne

Submissions from 1997

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Is cigarette smoking an effect modifier of the relation between antihypertensive therapy and blood lipids?, Carol A. Derby, L. Lapane, Anne Lamont Hume, Marilyn McFarland Barbour, and Richard A. Carleton

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Aspirin use for primary prevention of cardiovascular disease: A study of concomitant risk factors and health behaviors, Kate L. Lapane, Lamont Hume, Marilyn McFarland Barbour, and Richard A. Carleton

Submissions from 1996

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Immunological detection of type II collagen degradation: Use in the evaluation of anti-arthritic therapies, C. O. Chichester, J. Barrach, G. R. Srinivas, and P. Mitchell

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Issues in polypharmacotherapy: Focus on major depression, Robert L. Dufresne

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Electronic Compliance Assessment of Antifungal Prophylaxis for Human Immunodeficiency Virus-Infected Women, Sandra M. Geletko, Segarra, Kenneth H. Mayer, Theresa C. Fiore, Frances A. Bettencourt, Timothy P. Flanigan, and Michael N. Dudley

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Correlates of oral contraceptive use in two New England communities: 1981-1993, Anne L. Hume, M. Barbour, Kate L. Lapane, Patricia M. Flint, and Richard A. Carleton

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Clarithromycin Does Not Affect Phosphorylation of Zidovudine In Vitro, Khurram Z. Rana, W. Darnowski, Andy H. Strayer, and Michael N. Dudley

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Regulatory environment and psychotropic use in board-and-care facilities: Results of a 10-state study, Diana Spore, Mor, E. Paul Larrat, Jeffrey Hiris, and Catherine Hawes

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Reply, Diana Spore, Mor, E. Paul Larrat, Catherine Hawes, and Jeffrey Hiris

Submissions from 1995

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Predictors of future antihypertensive use in patients with mildly elevated blood pressure, M. M. Barbour, L. Hume, K. L. Lapane, C. A. Derby, and R. A. Carleton

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Efficacy of Constant Infusion of A-77003, an Inhibitor of the Human Immunodeficiency Virus Type 1 (HIV-1) Protease, in Limiting Acute HIV-1 Infection In Vitro, J. A. Bilello, A. Bilello, J. J. Kort, Michael N. Dudley, J. Leonard, and G. L. Drusano

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The Effect of High‐Dose Ascorbate Supplementation on Plasma Lipoprotein(a) Levels in Patients With Premature Coronary Heart Disease, Andrew G. Bostom, L. Hume, Charles B. Eaton, Joseph P. Laurino, Lisa R. Yanek, Mary S. Regan, William H. McQuade, Wendy Y. Craig, Gayle Perrone, and Paul F. Jacques

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Cardiovascular risk profiles of oral contraceptive users and nonusers: A population-based study, Patricia M. Flint, L. Lapane, Marilyn M. Barbour, Carol A. Derby, Richard A. Carleton, and Anne L. Hume

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Population Pharmacokinetics of Stavudine (d4T) in Patients with AIDS or Advanced AIDS-Related Complex, Cynthia M. Horton, N. Dudley, Sanjeev Kaul, Kenneth H. Mayer, Kathleen Squires, Lisa Dunkle, and Robert Anderson

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Is antidepressant use changing? Prevalence and clinical correlates in two New England communities, A. L. Hume, M. Barbour, K. L. Lapane, and R. A. Carleton

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Is the use of psychotropic drugs associated with increased risk of ischemic heart disease?, Kate L. Lapane, Zierler, Thomas M. Lasater, Marilyn M. Barbour, Richard Carleton, and Anne L. Hume

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Is a history of depressive symptoms associated with an increased risk of infertility in women?, Kate L. Lapane, Zierler, Thomas M. Lasater, Michael Stein, Marilyn M. Barbour, and Anne L. Hume

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Principles and approaches to pharmacoeconomics: The perspective of higher education, E. Paul Larrat

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Rewards and advancements for clinical pharmacy practitioners, M. Reynolds-Restino, Beardsley, S. Charland, M. Clotz, D. Covey, A. L. Hume, W. Linn, J. Perkins, M. Roy, N. Schultz, T. Welty, K. Lake, M. B. O'Connell, D. Angelo, A. Bandell, T. Cantu, T. Chin, V. Crane, and J. Jacobi

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Psychotropic Use Among Older Residents of Board and Care Facilities, Diana Spore, Mor, Jeffrey Hiris, E. Paul Larrat, and Catherine Hawes

Submissions from 1994

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Effect of 2',3'-Didehydro-3'-Deoxythymidine in an In Vitro Hollow-Fiber Pharmacodynamic Model System Correlates with Results of Dose-Ranging Clinical Studies, John A. Bilello, Bauer, Michael N. Dudley, Gerald A. Cole, and George L. Drusano

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Triazolam treatment controversy, P. Ghaeli, L. Dufresne, and C. A. Stoukides

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Cost-effectiveness study of nitrate therapy using a decision analysis methodology, E. P. Larrat

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Development of Alzheimer's disease special care units on a statewide level, E. Paul Larrat, L. McKernan-Markoff, Maureen Lareau, Jean Anderson, Marsha D. Fretwell, and John Stoukides

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Effects of certain antiarthritic agents on the synthesis of type II collagen and glycosaminoglycans in rat chondrosarcoma cultures, G. R. Srinivas, O. Chichester, H. J. Barrach, and A. L. Matoney

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Production of type II collagen specific monoclonal antibodies, G. R. Srinivas, O. Chichester, H. J. Barrach, V. Pillai, and A. L. Matoney

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Pharmacodynamics of Piperacillin Alone and in Combination with Tazobactam against Piperacillin-Resistant and -Susceptible Organisms in an In Vitro Model of Infection, Andy H. Strayer, H. Gilbert, Phil Pivarnik, Antone A. Medeiros, Stephen H. Zinner, and Michael N. Dudley

Submissions from 1993

The drug data base of the Pawtucket Heart Health Program: Development and description, M. M. Barbour, L. Hume, A. R. Assaf, and R. A. Carleton

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Correlates of postmenopausal estrogen use and trends through the 1980s in two Southeastern New England communities, Carol A. Derby, Lamont Hume, Marilyn McFarland Barbour, Janice B. Mcphillips, Thomas M. Lasater, and Richard A. Carleton

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Thioridazine improves affective symptoms in schizophrenic patients, R. L. Dufresne, Valentino, and D. J. Kass

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Pharmacotherapy in family medicine: current issues and strategies., A. L. Hume

Changing trends in antihypertensive therapy in two New England communities during the 1980s, A. L. Hume, M. Barbour, C. J. Willey, A. R. Assaf, K. L. Lapane, and R. A. Carleton

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Prevalence and Descriptors of Aspirin Use as an Antiplatelet Agent in Two New England Communities, Anne L. Hume, M. Barbour, Kate L. Lapane, Annlouise R. Assaf, and Richard A. Carleton

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Dose Ranging and Fractionation of Intravenous Ciprofloxacin against Pseudomonas aeruginosa and Staphylococcus aureus in an In Vitro Model of Infection, C. Randall Marchbanks, R. McKiel, Deborah H. Gilbert, Norman J. Robillard, Barbara Painter, Stephen H. Zinner, and Michael N. Dudley

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In Vitro Postantibiotic Effect Following Repeated Exposure to Imipenem, Temafloxacin, and Tobramycin, Betty J. McGrath, Randall Marchbanks, Deborah H. Gilbert, and Michael N. Dudley

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Quantitative immunoassays for type II collagen and its cyanogen bromide peptides, G. R. Srinivas, J. Barrach, and C. O. Chichester

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Effects of doxazosin on atherosclerosis in cholesterol-fed rabbits, Archie C. Swindella, N. Krupp, Thomas M. Twomey, Jack A. Reynolds, and Clinton O. Chichester

Submissions from 1992

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Update on the treatment of Alzheimer's disease. Drug therapy can ameliorate the behavioral manifestations of this disease, E. P. Larrat

Submissions from 1991

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Costs of antihypertensive therapy, Anne L. Hume

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A successful physician training program in cholesterol screening and management, Brian W. Jack, M. Gans, William McQuade, Larry Culpepper, Anita Lasswell, Anne L. Hume, Patrick T. Dowling, and Richard A. Carleton

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Attention tasks and EEG power spectra, Dominic A. Valentino and L. Dufresne

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Chronic DMI reduces thresholds for brain stimulation reward in the rat, Dominic A. Valentino, J. Riccitelli, and Robert L. Dufresne

Submissions from 1990

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Significance of "Extravascular" Protein Binding for Antimicrobial Pharmacodynamics in an In Vitro Capillary Model of Infection, Michael N. Dudley, Blaser, Deborah Gilbert, and Stephen H. Zinner

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Severe hyponatremia: An association with lisinopril?, A. L. Hume, W. Jack, and P. Levinson

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Compliance-related problems in the ambulatory population., E. P. Larrat, H. Taubman, and C. Willey

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Pharmacokinetics and Bioavailability of Intravenous-to-Oral Enoxacin in Elderly Patients with Complicated Urinary Tract Infections, C. Randall Marchbanks, J. Mikolich, Kenneth H. Mayer, Stephen H. Zinner, and Michael N. Dudley

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Stz-induced diabetes in shr and renovascular hypertensive rats: Dissociation between changes in arterial pressure and vascular collagen synthesis, Mark J. Mariani, C. Sessa, Clinton O. Chichester, and Robert L. Rodgers

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Clinical pharmacists in family practice residency programs, A. F. Shaughnessy and L. Hume

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Effects of a single inescapable swim on long-term brain stimulation reward thresholds, Dominic A. Valentino, L. Dufresne, and Anthony J. Riccitelli

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Pharmacokinetics of Enoxacin and Its Oxometabolite Following Intravenous Administration to Patients with Different Degrees of Renal Impairment, P. Van der Auwera, C. Stolear, B. George, and Michael N. Dudley

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Altered Theophylline Metabolism in Patients with Psoriasis, Dennis P. West, H. Fischer, Marilyn McFarland Barbour, Michael J. Cwik, Giuseppe Micali, and Virginia C. Fiedler

Submissions from 1989

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An account of action research investigating teacher change, Lingbiao Gao, Adcock, Malcolm Carr, Anne Hume, David Nicholson, Janet Silvester, and Daryl Smith

Applying quality of life data in practice. Considerations for antihypertensive therapy., A. L. Hume

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Converting-Enzyme Inhibitors in the Treatment of Hypertension, Anne Hume, Generali, William John Powell, Robert I. Henkin, Gordon H. Williams, J. Koch-Weser, and Haralambos Gavras

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Angiotensin‐Converting Enzyme Inhibitor‐Induced Cough, Anne L. Hume, L. Murphy, and Scott E. Lauerman

Submissions from 1988

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Effect of Protein Binding on Drug Penetration into Blister Fluid, Wen Chyi Shyu, Quintiliani, Charles H. Nightingale, and Michael N. Dudley