Date of Award

2017

Degree Type

Thesis

Degree Name

Master of Science in Nutrition and Food Science

Department

Nutrition and Food Sciences

First Advisor

Geoffrey Greene

Abstract

Background: Currently, there is no known patient reported outcome (PRO) instrument being used in clinical practice for the home parenteral nutrition (HPN) population. To address this gap, the Home Parenteral Nutrition-Patient Reported Outcome Questionnaire (HPN-PROQ) was developed for use during medical appointments or homecare visits. The purpose of this research is to provide evidence that the items and scales of the HPN-PROQ possess content validity, a crucial step in the process of questionnaire development.

Subjects: Qualitative sample included 32 HPN patients and quantitative sample included 13 expert home care clinicians (physicians, dietitian, pharmacists, registered nurses and patient advocates.)

Methods: In Phase I, cognitive interviews (CI) were conducted to evaluate HPN patients’ understanding of the instructions, items, and response scales on a draft HPN-PROQ. The draft HPN-PROQ was revised based on results of CIs. In Phase II, a revised draft was sent to expert clinicians to complete the Content Validity Index (CVI). Any item achieving a I-CVI kappa score ≤ 0.783 was removed. The Scale-CVI-Average (S-CVI/AVG) was calculated following a second round of CVI by a reduced expert panel.

Results: The final HPN-PROQ contains thirty-four items with an I-CVI score ≥ 0.783. The overall S-CVI/AVG score of the HPN-PROQ was 0.961.

Conclusion: This study provides evidence that the HPN-PROQ has acceptable content-validity and after future validation procedures, may be appropriate as a new tool for fostering dialogue between HPN patients and their clinicians.

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.