Theses/Dissertations from 2024
A C-MET RECEPTOR TARGETING NANOPARTICLE PLATFORM FOR COMBINATION THERAPY AGAINST HEPATOCELLULAR CARCINOMA, Subarna Das
DEVELOPING EFFECTIVE PHYSICAL AND CHEMICAL ADJUVANTS FOR INFLUENZA AND TUMOR VACCINES, Yibo Li
MECHANISTIC AND TOXICOKINETIC ANALYSIS OF PERFLUOROALKYL SUBSTANCES: PROTEOMICS APPROACH AND THE ROLE OF FATTY ACID BINDING (FABP), Seyed Mohamad Sadegh Modaresi
DNA DAMAGE, MODIFICATION AND REPAIR, Xianhao Zhou
Theses/Dissertations from 2023
A STUDY OF THE STRUCTURE-ACTIVITY RELATIONSHIPS OF CARCINOGENIC PROTEIN- AND DNA-BINDING CHEMICALS, Alicia M. Crisalli
MECHANISMS OF PPAR-ALPHA TARGETED THERAPY IN CHOLESTASIS: TRANSLATIONAL STUDIES, Gina Gallucci
ENHANCING THE EFFICACY OF INHALABLE NANOPARTICLE FORMULATIONS USING BIOMIMETIC LUNG SURFACTANT, Andrea Jennifer Gonsalves
OPIOIDS AND OPIOID USE DISORDER TREATMENT IN PREGNANCY: SPONTANEOUS ABORTION AND CHILDHOOD NEURODEVELOPMENTAL DISORDERS, Mennatullah Hasan
REAL-WORLD MEDICATION MANAGEMENT OF INDIVIDUALS WITH SICKLE CELL DISEASE, Abiodun John Ologunowa
EVALUATION OF THE TOXICOKINETIC MECHANISMS OF PERFLUOROALKYL SUBSTANCES: ACCUMULATION, DISTRIBUTION, AND ELIMINATION, Sangwoo Ryu
CHILDREN’S OUTCOMES AND MATERNAL OPIOID EXPOSURES DURING PREGNANCY, Shuang Wang
DEVELOPMENT OF LOCALIZED DRUG DELIVERY STRATEGIES FOR THE TREATMENT OF CANCERS AND INFECTIOUS DISEASES, Weizhou Yue
Theses/Dissertations from 2022
THE MECHANISTIC AND ETIOLOGICAL LINK BETWEEN BILE ACID DYSREGULATION AND PRETERM BIRTH, Syed Fayaz Ul Haq Hashmi
TREPROSTINIL IMPROVES HEPATIC CYTOCHROME P450 METABOLISM DURING RENAL ISCHEMIA REPERFUSION INJURY, Daniel Kelly
PREDICTORS OF EPI PROCOLON UTILIZATION, Eric Lamy
AN EVALUATION OF THE EFFECTIVENESS AND SAFETY OF DIRECT ORAL ANTICOAGULANTS VERSUS WARFARIN IN CHRONIC LIVER DISEASE, AND AFTER ANTICOAGULANT-RELATED MAJOR BLEEDING, Oluwadolapo D. Lawal
CHEMICAL BIOLOGY OF DNA ADDUCT REPAIR, BYPASS AND MUTAGENESIS, Rui Qi
CHEMICAL INVESTIGATION OF METABOLITES PRODUCED BY MARINE PSEUDOALTEROMONAS SPP., Margaret Rosario
A PROTEOMIC APPROACH TO UNDERSTANDING REGULATORY PATHWAYS IN NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD), Teresa Sierra
IMPACTS OF HYPERTENSION AND THROMBOSIS IN A RAT MODEL OF CEREBRAL AMYLOID ANGIOPATHY (rTg-DI), Aleksandra Stanisavljevic
PHYTOCHEMICAL ANALYSIS AND BIOLOGICAL EVALUATION OF MAPLE (Acer saccharum) SAP WATER, Kara Torrey
TRANSLATION AND VALIDATION OF MYELOID DERIVED SUPPRESSOR CELL PROTEOMIC TARGETS IN LIVER AND LUNG TUMORS, Justin Trickett
A MULTI-YEAR INVESTIGATION OF THE SPECIALIZED METABOLITE COMPOSITION OF TRICHODESMIUM SPP., Christopher William Via
Theses/Dissertations from 2021
PHARMACIST-ADMINISTERED PEDIATRIC INFLUENZA VACCINATION IN THE UNITED STATES, Dana M. Gates
DUAL-DRUG NANOPARTICLE FORMULATION FOR INHALED DELIVERY IN IDIOPATHIC PULMONARY FIBROSIS TREATMENT, Moez Ghumman
INVESTIGATING TOLFENAMIC ACID AND ITS ANALOGS AS POTENTIAL ALZHEIMER’S DISEASE THERAPEUTICS, Jaunetta Hill
HEPATOPROTECTIVE EFFECTS OF TREPROSTINIL DURING RENAL ISCHEMIA-REPERFUSION INJURY, Joyce Hou
EVALUATING NATURAL PRODUCT LIBRARIES WITH EMPHASIS ON IN VITRO PERMEABILITY WORKFLOWS, Riley D. Kirk
ANTI-INFLAMMATORY EFFECTS OF POLYPHENOL-ENRICHED EXTRACTS, Chang Liu
REAL-WORLD UTILIZATION AND EXPENDITURE OF TOP-DOWN AND STEP-UP THERAPY IN INFLAMMATORY BOWEL DISEASE, Kanya K. Shah
EVALUATION OF MEDICATIONS FOR OPIOID USE DISORDER ON OVERDOSE AND HEALTHCARE UTILIZATION IN THE US, Tianyu Sun
SELF-ADJUVANTED VIRUS-LIKE PARTICLE FOR SAFE AND HIGHLY IMMUNOGENIC VACCINATION, Yiwen Zhao
Theses/Dissertations from 2020
PERFLUOROOCTANESULFONIC ACID (PFOS) AS A POTENTIAL RISK FACTOR FOR LATE-ONSET ALZHEIMER’S DISEASE, Veronia Basaly
THE COMPARATIVE EFFECTIVENESS, SAFETY, AND COST OF ORAL P2Y12 ANTIPLATELET AGENTS FOLLOWING ACUTE CORONARY SYNDROMES, Nicholas Belviso
CHEMICAL INVESTIGATION OF BACTERIAL INTERACTIONS INVOLVING PATHOGENS, Hilary Joan Grant Ranson
EVALUATION OF KEY PERFLUOROALKYL SUBSTANCES TO INDUCE LIVER STEATOSIS IN MOUSE AND HUMAN MODELS, Emily Sara Marques
CHEMICAL INVESTIGATIONS OF PECTIC OLIGOSACCHARIDES FROM VACCINIUM MACROCARPON, Zhiyuan Peng
EVALUATION OF THE RELATIONSHIP BETWEEN CENTRALITY AND INDIVIDUAL-LEVEL CHARACTERISTICS AMONG PWID, Benjamin Skov
Theses/Dissertations from 2019
COMPARATIVE EFFECTS OF TOLFENAMIC ACID AND DONEPEZIL ON BEHAVIOR AND TAU PATHOLOGY BIOMARKER LEVELS, Abdullah G. Alharbi
POLYPHARMACY IN CANCER PATIENTS: HEALTH-RELATED QUALITY OF LIFE, EXPENDITURES, AND ADVERSE EVENTS, Zachary R. Babcock
USE OF HYPHENATED MASS SPECTROMETRY TO UNCOVER TRUE NAFLD EFFECT ON HUMAN DRUG DISPOSITION PROTEINS, Benjamin Joseph Barlock
DNA damage, repair and mutational spectrum, Ke Bian
ANTI-INFLAMMATORY EFFECTS OF POLYPHENOL-ENRICHED EXTRACTS AND THEIR GUT MICROBIAL METABOLITES, Nicholas A. DaSilva
BUDGET IMPACT ANALYSIS OF NOVEL ABUSE DETERRENT OPIOID FORMULATIONS IN A POPULATION OF CHRONIC OPIOID USE, Andrew Descoteaux
DEVELOPMENT OF PEDIATRIC ANTI-HIV FORMULATIONS WITH IMPROVED DISSOLUTION CHARACTERISTICS, Ryan Ivone
LASER-ASSISTED TRANSDERMAL DRUG DELIVERY AND VACCINATION, Prateek Kakar
AN ‘OMICS APPROACH TO DIET & STRUCTURE IMPACT ON PERFLUOROALKYL SUBSTANCE INDUCED LIVER DISEASE, Marisa Pfohl
AN OMICS BASED APPROACH FOR THE IDENTIFICATION OF BIOMARKERS IN NON-ALCOHOLIC FATTY LIVER DISEASE USING IN VITRO MODELS OF HEPATIC STEATOSIS, Anitha Saravanakumar
OVERCOMING CONTEMPORARY OBSTACLES IN DRUG DELIVERY VIA ACETALATED DEXTRAN PARTICLE FORMULATIONS, Nishan K. Shah
Theses/Dissertations from 2018
EXPRESSION AND ACTIVITY OF CYP2C8 AND 2C9 IN DIABETES MELLITUS AND NONALCOHOLIC FATTY LIVER DISEASE, Ghadah Alghaith
Economic Burden and Mortality Associated With Prescription Opioid Use, Hilary A. Aroke
MECHANISMS OF INDIVIDUAL VARIATION IN GLUCURONIDATION, SULFONATION, AND AMIDATION: BISPHENOL A AND BILE ACIDS, Adam Michael Auclair
Phytochemical Investigation of a Native North American Species, “Acer saccarinum” and an Endemic Saudi Arabian Species, “Euphorbia saudiarabica”, Abdullatif Bin Muhsinah
In Vitro Drug Metabolism and Population Pharmacokinetics as Tools for Elucidating Pharmacokinetic Variability, Enoch Cobbina
An Evaluation of Atypical Antipsychotic Use, Costs and Effectiveness in the Pediatric Population, Kellye A. Donovan
THE BIOLOGICAL FUNCTION OF HUMAN EPIDIDYMIS PROTEIN 4 IN EPITHELIAL OVARIAN CANCER, Nicole Elizabeth James
EFFECT OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) ON HEPATIC DRUG METABOLISM ENZYMES IN HUMAN, Rohitash Jamwal
REGULATION OF UBIQUITIN SPECIFIC PEPTIDASE 2 EXPRESSION BY FARNESOID X RECEPTOR IN HEPATOCELLULAR CARCINOMA, Christina Nadolny
Predictors of Concomitant Use of Prescription Opiods and Benzodiazepines in Rhode Island, Emily Patry
EFFECT OF ETHANOL ON GASTROINTESTINAL TIGHT JUNCTIONS AND P-GLYCOPROTEIN EXPRESSION AND FUNCTIONALITY, Armin Sadighi
Facilitated Excretion of Gold Nanoparticles by Copper Sulfide Nanoparticles Through the ATP7B Transporter, Xiaodong Wang
Theses/Dissertations from 2017
Biotransformation and Pharmacokinetic Evaluation of PF-5190457, A Novel Drug Candidate for Alcoholism, Sravani Adusumalli
The Physiological Glucagon Receptor in Rat Heart, Kevin Agostinucci
Concomitant Use of Central Nervous System Stimulants and Depressants Prescribed in Rhode Island, Aram Babcock
Conformational Insights Into Aminobiphenyl-Modified DNA: Implications for Mutation and Repair, Ang Cai
Using Natural Products to Treat Resistant and Persistent Bacterial Infections, Robert W. Deering
Predictors of Infection in Rheumatoid Arthritis Patients Using Anti-Tumor Necrosis Factor Agents, Tasia Liu
Circadian Rhythm: A Functional Connection Between SHP and DEC1 Transcription Factor, Marek Matczynski Marczak
Novel Pharmacological Action of Clozapine at D2 Dopamine Receptors, Joseph Michael Schrader
CES Involved Inhibition and Regulation, Yuanjun Shen
Cardiovascular Adverse Events in Patients Receiveing QT Interval Prolonging Medications, Yizhou Ye
Theses/Dissertations from 2016
Effect of Disease State on Human Carboxylesterase 1 Expression and Activity, Abdullah Aljutayli
Healthcare Costs and Impact of Medication Adherence on Outcomes in Patients on Novel Anticoagulant Therapy, Chinmay Deshpande
A Study of the Increased Risk of Bleeding Events in Patients with Blood Clotting Disorders, Associated with Antidepressant Medication Use, Adam Ehrenborg
Retrospective Cohort Study of Tobacco Dependence Treatment Patterns in a US Commercially Insured Population, Elizabeth Anne MacLean
Factors Associated With Sustained Release Psychostimulant Prescriptions for Pediatric ADHD, Robert McConeghy
Isolation, Synthesis, and Metabolism of Polyphenols: Stilbenoids, Gallotannins and Ellagitannins, Daniel B. Niesen
Antimicrobial Resistance Patterns and Protective Effects of Statins in Bacteremic Patients, Ajinkya Pawar
Investigations on Biologically Active Carbohydrates from Natural Sources, Jiadong Sun
Measuring Adherence with Antidepressant Medication: Comparison of HEDIS and PDC Methodologies, Carmen Monica Telinoiu
Cadmium Contributes to Breast Cancer Development by Influencing Cell Adhesion Network, Zhengxi Wei
Bile Acids and Premature Labor in Intrahepatic Cholestasis of Pregnancy, Sangmin You
Theses/Dissertations from 2015
A Cross-Sectional Analysis of Bronchodilator Prescribing in COPD and Cardiovascular Comorbidity, Damilola Tejumola Adesanoye
NRF as an Oxidative Stress and Nutrient Responsive Transcription Factor in Calorie Restriction, Laura Armstrong
Synthesis of 2-Amino-α-Carboline and Analogues Relevant for Structural Investigations of the Corresponding DNA Adducts, Matthew S. Blake
Tolfenamic Acid: A Potential Modifier of Tau Protein in Alzheimer's Disease, Joanna K. Chang
CHEMICAL INVESTIGATION OF CANDIDATE PROBIOTICS IN AQUACULTURE AND FORMULATION OF A PROBIOTIC AGENT FOR OYSTER LARVICULURE, Christine Anh Dao
Therapeutic Drug Monitoring of Immunosuppresive, Mwlod A. Ghareeb