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Theses/Dissertations from 2014

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STRUCTURAL AND CONFORMATIONAL INSIGHTS INTO BULKY ARYLAMINE-INDUCED MUTAGENESIS, Lifang Xu

Theses/Dissertations from 2013

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Pharmacodynamic Mechanisms of Tolfenamic Acid Induced SP1 Degradation Relative to Alzheimer's Disease Pathology, Lina I. Adwan

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Applying QbD and Pat in Biological Manufacturing for “Continued Process Verification”, Prakash Bedre

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Trends in the Use of Preventive Care by Women in the U. S. General Population, Erin Bennett

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Associations Between Patient Characteristics and Utilization in a Commercial Schizophrenia Population, Thomas Joseph Bunz

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Phytochemicals from the Roots of Northern Highbush Blueberry (Vaccinium Corymbosum), Amanda Cirello

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Effect of Metabolic Disease and Xenobiotic Exposure on Hepatic ATP-Binding Cassette (ABC) Drug Transporter Expression, Ajay Chowdary Donepudi

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Sequence Effects on the Repair and Replication of Arylamine-DNA Adducts, Vipin Jain

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Predictors of Non-Vaccination Against Human Papillamovarius Among Us Women Aged 18-26, H. Elsa Larson

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Prediction of Heptatic and Renal Clearance in Pediatric Populations: A "Bottom-Up" Approach Versus "Top-Down" Recognition of Covariates, Hong Lu

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Model-Based Approaches to Characterize Clinical Pharmacokinetics of Atorvastatin and Rosuvastatin in Disease State, Joyce Macwan

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Role of Nuclear Factor E2 Related Factor 2 (NRF2) in Development of Steatosis and Drug Transporter Alterations, Vijay RS More

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Cyclic Peptides: Design, Characterization, Self-Assembly, and Applications as Nano Drug Delivery Systems, Amir Nasrolahi Shirazi

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Use and Unintended Consequences of Antidepressant Medications by Depressed Older Adults, Eun Sun Noh

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Compounds from A. Platanoides Bark, V. Corymbosum Roots & Topical Formulations using Maple Syrup, Raed Omar

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Structural and Conformational Probing of 2-Acetylaminofluorene-Modified -1, -2 and -3 Slipped Mutagenic Intermediates, Anusha Sandineni

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Producing In-Situ Nanoparticles of Griseofulvin using Supercritical Antisolvent Methodology, Pratik Sheth

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Effect of Manufacturing Methods Used in the Stability of Amorphous Solid Solutions and Predictions to Test them, Kaoru Tominaga

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Suppression of PXR Expression by Endoplasmic Reticulum Stress and Microrna, Thaveechai Vachirayonstien

Theses/Dissertations from 2012

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NRF2 AS A NUTRIENT SENSITIVE TRANSCRIPTION FACTOR, Supriya Kulkarni

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Brain Penetration of Tolfenamic Acid and its Ability to Enhance the Cognitive Functions and to Lower Amyloid Pathology in Animal Models of Alzheimer's Disease, Gehad Mohammed Subaiea

Theses/Dissertations from 2011

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THE FORMULATION OF NATURALLY OCCURING POLYPHENOLIC NUTRACEUTICAL AGENTS USING HOT-MELT EXTRUSION, Aditya Duvuri

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BIOFILM PRODUCTION BY CLINICAL STAPHYLOCOCCUS AUREUS AND ITS INHIBITION BY HYPERICUM METABOLITES, Simon Antranik Sarkisian

Theses/Dissertations from 2010

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Drug Safety Issues Focusing on Liver and Pancreas Toxicity, Thamir M. Alshammari

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Farnesoid X Receptor Modulation by Systematic Ligands of Translocator Protein (18KDA), Linnea Elsa Anderson

Theses/Dissertations from 2008

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The Formulation and Process Development of a Novel Multiparticulate Extended Release Pharmaceutical Delivery Platform for a Highly Water Soluble Compound, Cyrus D. Agarabi

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In Vitro Effects of Emollient Substances on Release of Ketorolac Tromethamine, Burcak Alioglu

Theses/Dissertations from 2006

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Identification and Minimization of Protein Loss During the Manufacturing of a Beta Domain Deleted Recombinant Human Factor VIII, Cyrus Agarabi

Theses/Dissertations from 2004

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USING PHARMACY CLAIMS DATA TO EVALUATE ADHERENCE AND PERSISTENCE WITH PRESCRIBED MEDICATIONS IN PATIENTS WITH DIABETES MELLITUS, Pamela J. Johnson

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A MECHANISTIC STUDY TO IDENTIFY PHYSICALLY STABLE AMORPHOUS SOLID DISPERSION, Madhav Vasanthavada

Theses/Dissertations from 2003

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Drug Benefit Plans for Elderly Under Managed Care and Utilization of Lipid Lowering Agents, Susan M. Abughosh

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Using the Medical Expenditure Panel Survey (MEPS) to Assess Antibiotic Utilization in Acute Respiratory Tract Infections, Muhammed S. Al-Sultan

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EXAMPLES OF POPULATION PHARMACOKINETIC MODELING IN DRUG DEVELOPMENT USING NONMEM, Julie M. Jones

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THE DEC1 TRANSCRIPTION FACTOR: ONCOGENIC INVOLVEMENT AND MOLECULAR MECHANISMS ON TRANSCRIPTION REGULATION, Yuxin Li

Theses/Dissertations from 2002

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Rational Approaches to the Regulation of Nonprescription Medicines, Anand S. Achanta

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MECHANISTIC STUDIES TO ELUCIDATE THE ROLE OF LIPID VEHICLES ON SOLUBILITY, FORMULATION AND BIOA VAILABILITY OF POORLY SOLUBLE COMPOUNDS, Inayet Dumanli

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EFFECT OF pH AND TEMPERATURE ON CONFORMATIONAL CHANGES OF A HUMANIZED MONOCLONAL ANTIBODY, Sejal Gandhi

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EFFECT OF CRYSTALLINE TO AMORPHOUS CONVERSIONS ON SOLUBILITY OF CEFUROXIME AXETIL, Tooba Murshedkav

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MOISTURE INTERACTIONS WITH PHARMACEUTICALPOL YMERJC FILM COATINGS, Ravi S. Pappu

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PARTICLE FORMATION BY RAPID EXPANSION OF SUPERCRITICAL SOLUTIONS, Chandra S. Vemavarapu

Theses/Dissertations from 2001

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COMPARING SEVERAL SELF-REPORT MEASURES OF ADHERENCE WITH MEDICATIONS FOR HIV WITH ELECTRONICALLY MONITORED MEDICATION ADHERENCE., Neelam Awte

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PREDICTORS OF PATIENT REPORTED MEDICATION ADHERENCE TO ANTIRETROVIRAL THERAPY, Zlata Cerimagic

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A MECHANISTIC STUDY OF FLOW AND COMPRESSION BEHAVIOR OF PHARMACEUTICAL POWDERS, Yogita Desai

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DESIGN, SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NOVEL ANTIMICROBIAL PEPTIDES, Khaled Elsaid

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WHICH PATIENTS RETURN TO ANTIHYPERTENSIVE DRUG THERAPY AFTER DISCONTINUATION?, Prafulla S. Girase

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HYPOGLYCEMIC DRUG UTILIZATION AND ADHERENCE TO PRESCRIBED REGIMENS: A PHARMACOEPIDEMIOLOGIC STUDY USING RETAIL PHARMACY DATA, Stephen Jon Kogut

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FACTORS AFFECTING ADHERENCE TO ANTIRETROVIRAL THERAPY IN HIV POSITIVE INJECTION DRUG USERS (IDUs) AND NON-IDUs., Dipti R. Salgaonkar

Theses/Dissertations from 2000

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DEVELOPMENT, CHARACTERIZATION AND EVALUATION OF A PULSED-RELEASE TABLET DOSAGE FORM FOR LOW DOSE WATER SOLUBLE DRUGS, Suresh Palaniswamy

Theses/Dissertations from 1999

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Elucidation of Hot Melt Wax Coating Systems, Anand S. Achanta

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Determination and Characterization of Water, Oil and Surfacant Induced Variations in Isotropic Domains of Plurololeique CC 497 / Labrasol System, Anchalee Ain-Ai

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CHARACTERIZATION OF A PUTATIVE TRANSCRIPTION FACTOR, Maowen Hu

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THE APPLICATION OF THE POPULATION APPROACH TO PHARMACOKINETICS IN DRUG DEVELOPMENT, Kimberley Anne Jackson

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REGULATION OF STABILITY OF MARKETED PHARMACEUTICALS, Brahmaiah Kommanaboyina

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THE EFFECT OF DEMOGRAPHICS AND PLAN CHARACTERISTICS ON THE COST OF PHARMACEUTICALS IN A PRIVATE THIRD-PARTY PRESCRIPTION PROGRAM, Soyal R. Momin

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PHARMACODYNAMIC PARAMETERS: INFLUENCE ON DOSE-RESPONSE RELATIONSHIP AND ESTIMATION, Suzette F. Rashed

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PRESCRIBING PATTERNS AND CLINICAL OUTCOMES IN ASTHMATIC CHILDREN: A HISTORICAL COHORT STUDY, Alexandra Jane Ward

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Antihypertensive Pharmacotherapy: Does Prescribing Follow National Guideline Recommendations?, Edward Roy Westrick

Theses/Dissertations from 1998

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PREDICTORS OF COMPLIANCE OF AIDS PATIENTS ON PROTEASE INHIBITORS, Tina Gursahani

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CONTROLLED DRUG DELIVERY FROM A NOVEL INJECTABLE IN SITU FORMED BIODEGRADABLE PLGA MICROSPHERE SYSTEM, Rajeev Jain

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THE DEVELOPMENT, CHARACTERIZATION AND EVALUATION OF A NOVEL MULTI-UNIT ERODING MATRIX SYSTEM FOR POORLY SOLUBLE DRUGS, Ketan Arvind Mehta

Theses/Dissertations from 1996

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THE EFFECT OF COMPRESSION FORCE ON THE NEAR-INFRARED SPECTRA OFT ABLET DOSAGE FORMS, Karen Marie Morisseau

Theses/Dissertations from 1995

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A COMPARATIVE ANALYSIS OF THE EFFECTIVENESS OF DRUGGED DRIVING VS. DRUNK DRIVING, Ernest DiFazio Jr.

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The Influence of Formulation and Device Variables on the Intransasal Absorption of Salmon Calcitonin, Ramneik Dua

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THIRD PARTY REIMBURSEMENT OF COMPOUNDED PRESCRIPTIONS, Renuka Nair

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An Investigation of the Material and Process Variables in Pharmaceutical Wet Granulation, George Sienkiewicz

Theses/Dissertations from 1994

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A CRITICAL INVESTIGATION OF THE IMPACT OF LABELING AND ADVERTISING ON THE SAFE AND EFFECTIVE USE OF RX-TO-OTC SWITCH PRODUCTS, Nancy Maria Hewitt

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SYSTEMATIC STUDIES TO EVALUATE THE EFFECTS OF VEHICLES ON THE IN VIVO DRUG DELIVERY TO THE SKIN, Sudhanva R. Marathe

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THE DEVELOPMENT OF PHOTOCROSSLINKABLE HYDROXETHYLCELLULOSE MEMBRANES FOR SUSTAINED RELEASE PHARMACEUTICAL PREPARATIONS, Gary Van Savage

Theses/Dissertations from 1993

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THE EFFECT OF THE OMNIBUS BUDGET RECONCILIATION ACT OF 1980 ON COST ISSUES RELATED TO THE PROCUREMENT OF PHARMACEUTICALS, William Bilotti

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PHYSTCOCHEMICAL PROPERTIES AFFECTING THE PERCUTANEOUS ABSORPTION OF NIFEDIPINE, Emilio Squillante

Theses/Dissertations from 1991

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The Impact of the Rhode Island Duplicate Prescription Law on Prescribing Practices for Schedule II Drugs, Bridgit A. Anness

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Optimization and Its Applications on Pharmaceutical Conventional and Extended Release Solid Dosage Forms, Hann Rong Chueh

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DEVELOPMENT OF A NEW NON-SURGICAL PERFUSION TECHNIQUE TO EVALUATE NASAL DRUG DELIVERY, Polireddy Dondeti

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OPTIMIZATION OF IBUPROFEN FORMULATION: MOLECULAR PHARMACEUTICS OF THE BIOLOGICALLY ACTIVE STEREOISOMER, Alain Joseph Romero

Theses/Dissertations from 1989

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CHANGES IN CARDIAC FUNCTION DUE TO THE INTERACTIONS OF DIABETES AND HYPERTENSION IN THE RAT, Amy Jane Davidoff

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OPTIMIZATION AND USE OF TALC IN DIRECT COMPRESSION TABLET FORMULATIONS, Shabbir S. Dawoodbhai

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THE EFFECTS OF ALBUTEROL AND CHRONIC ANTIDEPRESSANTS ON INTRACRANIAL SELF-STIMULATION REWARD THRESHOLDS, Robert Louis Dufresne

Theses/Dissertations from 1988

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FORMULATION OF AN ORAL CONTROLLED RELEASE DOSAGE FORM FOR NIFEDIPINE, Varun Garg

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A PHYSICO-CHEMICAL STUDY OF THE COMPLEXATION OF CYCLODEXTRINS WITH PHARMACEUTICAL SUBSTANCES, Francois A. Menard

Theses/Dissertations from 1987

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PRELIMINARY INVESTIGATION INTO THE SOLUBILITY OF AZQ (NSC - 182986), AN ANTI CANCER AGENT, Lekunutu Casalis Matima

Theses/Dissertations from 1986

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OPIATE RECEPTOR SUBTYPE MODULATION OF DOPAMINERGIC ACTIVITY THE EFFECTS OF MU, KAPPA AND SIGMA OPIATES ON THE DEVELOPMENT OF DOPAMINERGIC SUPERSENSITIVITY, Robert W. Dunn

Theses/Dissertations from 1985

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An Investigation of the Effect of Some Formulation and Manufacturing Variables on the Wet Granulation Process, Sambasiva Rao Ghanta

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THE EFFECT OF DEVICE CHARACTERISTICS ON NITROGLYCERIN RELEASE FROM A TRANSDERMAL PATCH, Karen M. Guilmette

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DRUG- CYCLODEXTRIN INCLUSION COMPOUNDS. STUDIES OF THE FORMULATION OF PHARMACEUTICAL PRODUCTS CONTAINING CYCLODEXTRINS., Ramachandra P. Hegde

Theses/Dissertations from 1984

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STUDIES OF THE STABILITY, PROTEIN BINDING AND PHARMACOKINETICS OF DOXORUBICIN DSING A NEW ASSAY METHOD, Tyzz-Yun Chen

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SOME STUDIES OF THE FORMULATION AND EVALUATION OF TABLETS WITH SPECIAL REFERENCE TO DIRECT COMPRESSION SUGARS, Clive Ongeri Ondari

Theses/Dissertations from 1982

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Age Related Changes in the Induction of Hepatic Mixed-Function Monooxygenase System in Miniature Pigs: Effects of Pentachloroanisole, Pentachlorophenol and Phenobarbital, Alan Paul Agins

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AN INVESTIGATION OF THE POTENTIAL OF SOY CELLULOSE AS A TABLET DISINTEGRANT, Divyakant S. Desai

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THE INTEGRATED RELATIONSHIPS OF PROTRIPTYLINE, THYROID STATUS AND NORADRENERGIC MECHANISMS IN RAT BRAIN, Edward A. Kaiser

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TRICYCLIC ANTIDEPRESSANTS AND SERUM IONIZED CALCIUM, Girolamo A. Ortolano

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AN INVESTIGATION OF SOME FACTORS CONTROLLING SOLUTE TRANSPORT ACROSS LIQUID MEMBRANES, Andrea Panaggio

Theses/Dissertations from 1981

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Human Pharmacokinetics of 5-Formyl Tetrahydrofolate, Bruce Kenneth Birmingham

Theses/Dissertations from 1980

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A MECHANISM OF ACTION OF GOLD IN RHEUMATOID ARTHRITIS. A BIOCHEMICAL AND MORPHOLOGICAL INVESTIGATION OF THE DIRECT EFFECT OF GOLD SODIUM THIOMALATE (GST) ON HUMAN SYNOVIAL CELLS IN CULTURE, Ronald Lee Goldberg

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Some aspects of formulation and optimization of tablet disintegrants in direct compression systems, Edward M. Rudnic

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THE ANXIOMIMETIC PROPERTIES OF PENTYLENETETRAZOL IN THE RAT, Gary Terence Shearman

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CHARACTERIZATION OF THE FIBROTIC LESION IN DIBUTYLTIN-INDUCED EXPERIMENTAL LIVER INJURY, Jeannee Karen Yermakoff

Theses/Dissertations from 1979

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A Study of Trends in Pharmacy Consumer Credit Operations, Harold S. Abbott

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STUDIES ON EFFECT OF MOLECULAB STRUCTURE OF SOME AROMATIC COMPOUNDS ON THEIR UPTAKE RATES BY A LIQUID MEMBRANE SYSTEM, Rao Nagamasthan Chilamkurti

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CELL PROLIFERATION AND COLLAGEN SYNTHESIS IN EXPLANT CULTURES OF ARTERIOSCLEROTIC RABBIT AORTA, Douglas Otto Fisher

Theses/Dissertations from 1978

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THE TOXICITY OF PARATHION TO ORCONECTES RUSTICUS AND VIVIPARUS MALLEATUS, Leslie Alan Goldsmith