Date of Award

2022

Degree Type

Dissertation

Degree Name

Doctor of Philosophy in English

Department

English

First Advisor

Peter Covino

Abstract

Gold has unique optical properties, localized surface plasmon resonance (LSPR), as well as strong interaction with thiolated molecules. For this reason, gold nanoparticles were used as shell materials for the multifunctional platforms. The prepared nanoparticles were further functionalized with different thiolated molecules depending on their specific applications. Magnetic nanoparticles were chosen for their unique magnetic relaxation properties and due to their response to external magnetic field. Self-assembled magnetic nanoparticle clustering is explored to tune their relaxation behavior in a magnetic field. In addition, anticancer drug doxorubicin (DOX) loading and ‘on demand’ release of the loaded DOX was monitored in the presence of a radio frequency field. The results of these studies will contribute to the process of advancing the nanomaterial mediated field in biomedical and environmental applications.

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Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

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