High-fructose corn syrup, energy intake, and appetite regulation
Document Type
Article
Date of Original Version
12-1-2008
Abstract
High-fructose corn syrup (HFCS) has been implicated in excess weight gain through mechanisms seen in some acute feeding studies and by virtue of its abundance in the food supply during years of increasing obesity. Compared with pure glucose, fructose is thought to be associated with insufficient secretion of insulin and leptin and suppression of ghrelin. However, when HFCS is compared with sucrose, the more commonly consumed sweetener, such differences are not apparent, and appetite and energy intake do not differ in the short-term. Longer-term studies on connections between HFCS, potential mechanisms, and body weight have not been conducted. The main objective of this review was to examine collective data on associations between consumption of HFCS and energy balance, with particular focus on energy intake and its regulation. © 2008 American Society for Nutrition.
Publication Title, e.g., Journal
American Journal of Clinical Nutrition
Volume
88
Issue
6
Citation/Publisher Attribution
Melanson, Kathleen J., Theodore J. Angelopoulos, Von Nguyen, Linda Zukley, Joshua Lowndes, and James M. Rippe. "High-fructose corn syrup, energy intake, and appetite regulation." American Journal of Clinical Nutrition 88, 6 (2008). doi: 10.3945/ajcn.2008.25825E.