Possible therapeutic effects of transcutaneous electrical stimulation via concentric ring electrodes
Document Type
Conference Proceeding
Date of Original Version
7-1-2010
Abstract
Even with the latest advancements in antiepileptic drugs (AEDs) there are still many persons whose seizures are not controlled. There are also side effects reported associated with the AEDs. Electrical stimulation of the brain has shown promise toward controlling seizures. However, most brain stimulation techniques involve invasive procedures to implant electrodes and electronic stimulators. There are no conclusive descriptions of where to place the implanted electrodes to control seizures. Noninvasive electrical stimulation does not require the risks of implantation, and the electrodes can be moved easily as needed to determine where they may be the most effective in reducing seizure activity. Herein we review the progress of our group in the development of noninvasive electrical stimulation via concentric ring electrodes to control seizures in rats induced by penicillin G, pilocarpine, and pentylenetetrazole (PTZ). © 2010 International League Against Epilepsy.
Publication Title, e.g., Journal
Epilepsia
Volume
51
Issue
SUPPL. 3
Citation/Publisher Attribution
Besio, Walter G., Karen N. Gale, and Andrei V. Medvedev. "Possible therapeutic effects of transcutaneous electrical stimulation via concentric ring electrodes." Epilepsia 51, SUPPL. 3 (2010). doi: 10.1111/j.1528-1167.2010.02617.x.