Transcutaneous focal electrical stimulation via concentric ring electrodes reduces synchrony induced by pentylenetetrazole in beta and gamma bands in rats
Document Type
Article
Date of Original Version
4-1-2011
Abstract
Epilepsy is a neurological disorder that affects approximately one percent of the world population. Anti-epileptic drugs are ineffective in 25∼30% of cases. Electrical stimulation to control seizures may be an additive therapy. We applied noninvasive transcutaneous focal electrical stimulation (TFES) via concentric ring electrodes on the scalp of rats after inducing seizures with pentylenetetrazole. We found a significant increase in synchrony within the beta-gamma bands during seizures and that TFES significantly reduced the synchrony of the beta-gamma activity and increased synchrony in the delta band. © 2011 World Scientific Publishing Company.
Publication Title, e.g., Journal
International Journal of Neural Systems
Volume
21
Issue
2
Citation/Publisher Attribution
Besio, Walter G., Xiang Liu, Liling Wang, Andrei V. Medvedev, and Kanthaiah Koka. "Transcutaneous focal electrical stimulation via concentric ring electrodes reduces synchrony induced by pentylenetetrazole in beta and gamma bands in rats." International Journal of Neural Systems 21, 2 (2011). doi: 10.1142/S0129065711002729.