Title

Synthesis of a β-CCT-lanthanide conjugate for binding the dopamine transporter

Document Type

Article

Date of Original Version

3-7-2015

Abstract

The development of a β-CCT-lanthanide conjugate that binds the dopamine transporter (DAT) with high affinity (Kd = 303 nM) is described. Contrast agents such as the one described herein could be used as molecular probes to directly study the binding of small molecules to receptors such as DAT via MRI, PET or SPECT. This journal is

Publication Title

Organic and Biomolecular Chemistry

Volume

13

Issue

9

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