Document Type
Article
Date of Original Version
1-16-2015
Abstract
A novel protocol for the regioselective intermolecular amination of various arenes has been developed. By using an I(III) oxidant in the presence of a Au(I) catalyst, a direct and novel route for regioselectively accessing a variety of substituted aniline moieties has been achieved with yields as high as 90%. Mechanistic insight suggests that regioselectivity can be predicted based on electrophilic aromatic metalation patterns.
Publication Title, e.g., Journal
Organic Letters
Volume
17
Issue
2
Citation/Publisher Attribution
Marchetti, Louis, Abhishek Kantak, Riley Davis, and Brenton Deboef. "Regioselective gold-catalyzed oxidative C-N bond formation." Organic Letters 17, 2 (2015): 358-361. doi: 10.1021/ol5034805.
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