Explore master's theses and doctoral dissertations from graduates of the URI Department of Biomedical and Pharmaceutical Sciences.

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Theses/Dissertations from 1995

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THE EFFECTS OF METHYLENE BLUE PRETREATMENT ON GLOBAL ISCHEMIA IN THE ISOLATED RAT HEART, Stephen Robert Gorman

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An Investigation of the Material and Process Variables in Pharmaceutical Wet Granulation, George Sienkiewicz

Theses/Dissertations from 1994

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A CRITICAL INVESTIGATION OF THE IMPACT OF LABELING AND ADVERTISING ON THE SAFE AND EFFECTIVE USE OF RX-TO-OTC SWITCH PRODUCTS, Nancy Maria Hewitt

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SYSTEMATIC STUDIES TO EVALUATE THE EFFECTS OF VEHICLES ON THE IN VIVO DRUG DELIVERY TO THE SKIN, Sudhanva R. Marathe

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FORMULATION OF AN ORAL MODIFIED RELEASEDOSAGE FORM OF AN ADRENERGIC DRUG, Suresh Palaniswamy

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STUDY OF MICROENCAPSULATED PRODUCTS WITH RESPECT TO THEIR ABILITY TO PREVENT INCOMPATIBILITIES, Harish K. Pimplaskar

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THE DEVELOPMENT OF PHOTOCROSSLINKABLE HYDROXETHYLCELLULOSE MEMBRANES FOR SUSTAINED RELEASE PHARMACEUTICAL PREPARATIONS, Gary Van Savage

Theses/Dissertations from 1993

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PHYSTCOCHEMICAL PROPERTIES AFFECTING THE PERCUTANEOUS ABSORPTION OF NIFEDIPINE, Emilio Squillante

Theses/Dissertations from 1991

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Optimization and Its Applications on Pharmaceutical Conventional and Extended Release Solid Dosage Forms, Hann Rong Chueh

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DEVELOPMENT OF A NEW NON-SURGICAL PERFUSION TECHNIQUE TO EVALUATE NASAL DRUG DELIVERY, Polireddy Dondeti

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FLUORESCENCE POLARIZATION IMMUNOASSAY OF VITREOUS HUMOR TO DETECT DRUG USE, Nancy Round Haley

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OPTIMIZATION OF IBUPROFEN FORMULATION: MOLECULAR PHARMACEUTICS OF THE BIOLOGICALLY ACTIVE STEREOISOMER, Alain Joseph Romero

Theses/Dissertations from 1990

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ROLE OF INTRACELLULAR THlOL STATIUS AND CALCIUM HOMEOSTASIS IN MYOCARDIAL CELL INJURY, Cyrus M. Dhanbhoora

Theses/Dissertations from 1989

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MYOCARDIAL ORNITHINE DECARBOXYLASE OF HYPERTENSIVE AND DIABETIC RATS: EFFECTS OF INSULIN AND TRIIODOTHYRONINE TREATMENT, Michael E. Christe

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CHANGES IN CARDIAC FUNCTION DUE TO THE INTERACTIONS OF DIABETES AND HYPERTENSION IN THE RAT, Amy Jane Davidoff

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OPTIMIZATION AND USE OF TALC IN DIRECT COMPRESSION TABLET FORMULATIONS, Shabbir S. Dawoodbhai

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THE EFFECTS OF ALBUTEROL AND CHRONIC ANTIDEPRESSANTS ON INTRACRANIAL SELF-STIMULATION REWARD THRESHOLDS, Robert Louis Dufresne

Theses/Dissertations from 1988

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FORMULATION OF AN ORAL CONTROLLED RELEASE DOSAGE FORM FOR NIFEDIPINE, Varun Garg

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THE EFFECT OF STREPTOZOTOCIN-INDUCED DIABETES ON SYSTOLIC ARTERIAL PRESSURE AND AORTIC COLLAGEN BIOSYNTHESIS IN THE GOLDBLATT RENOVASCULAR HYPERTENSIVE RAT, Mark J. Mariani

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A PHYSICO-CHEMICAL STUDY OF THE COMPLEXATION OF CYCLODEXTRINS WITH PHARMACEUTICAL SUBSTANCES, Francois A. Menard

Theses/Dissertations from 1986

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ROLE OF VASCULAR REACTIVITY AND COLLAGEN BIOSYNTHESIS IN THE DEPRESSOR EFFECT OF STREPTOZOTOCIN IN THE SPONTANEOUSLY HYPERTENSIVE RAT, Paul H. Breault

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OPIATE RECEPTOR SUBTYPE MODULATION OF DOPAMINERGIC ACTIVITY THE EFFECTS OF MU, KAPPA AND SIGMA OPIATES ON THE DEVELOPMENT OF DOPAMINERGIC SUPERSENSITIVITY, Robert W. Dunn

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THE DEPRESSOR EFFECT OF STREPTOZOTOCIN - INDUCED DIABETES IN SPONTANEOUSLY HYPERTENSIVE RATS: THE ROLE OF VASCULAR COLLAGEN SYNTHESIS, William C. Sessa Jr.

Theses/Dissertations from 1985

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BUPROPION AND THIOTHIXENE COMPARED WITH PLACEBO AND THIOTHIXENE IN THE TREATMENT OF DEPRESSED SCHIZOPHRENIC INPATIENTS, Robert Louis Dufresne

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An Investigation of the Effect of Some Formulation and Manufacturing Variables on the Wet Granulation Process, Sambasiva Rao Ghanta

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THE EFFECT OF DEVICE CHARACTERISTICS ON NITROGLYCERIN RELEASE FROM A TRANSDERMAL PATCH, Karen M. Guilmette

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DRUG- CYCLODEXTRIN INCLUSION COMPOUNDS. STUDIES OF THE FORMULATION OF PHARMACEUTICAL PRODUCTS CONTAINING CYCLODEXTRINS., Ramachandra P. Hegde

Theses/Dissertations from 1984

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STUDIES OF THE STABILITY, PROTEIN BINDING AND PHARMACOKINETICS OF DOXORUBICIN DSING A NEW ASSAY METHOD, Tyzz-Yun Chen

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SOME STUDIES OF THE FORMULATION AND EVALUATION OF TABLETS WITH SPECIAL REFERENCE TO DIRECT COMPRESSION SUGARS, Clive Ongeri Ondari

Theses/Dissertations from 1983

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THE EFFECT OF CHRONICALLY ADMINISTERED LSD ON THE SEROTONERGIC NERVOUS SYSTEM OF THE RAT, Bruce E. Fishman

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BINDING AFFINITY OF BETA-ADRENOCEPTORS IN ATRIA OF STREPTOZOTOCIN-INDUCED DIABETIC AND NORMAL RATS, Edward James McKenna

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COLLAGENASE AND ELASTASE ACTIVITIES IN HUMAN AND MURINE CANCER CELLS AND THEIR MODULATION BY DIMETHYLFORMAMIDE, David Ray Olsen

Theses/Dissertations from 1982

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Age Related Changes in the Induction of Hepatic Mixed-Function Monooxygenase System in Miniature Pigs: Effects of Pentachloroanisole, Pentachlorophenol and Phenobarbital, Alan Paul Agins

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THE INTEGRATED RELATIONSHIPS OF PROTRIPTYLINE, THYROID STATUS AND NORADRENERGIC MECHANISMS IN RAT BRAIN, Edward A. Kaiser

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TRICYCLIC ANTIDEPRESSANTS AND SERUM IONIZED CALCIUM, Girolamo A. Ortolano

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AN INVESTIGATION OF SOME FACTORS CONTROLLING SOLUTE TRANSPORT ACROSS LIQUID MEMBRANES, Andrea Panaggio

Theses/Dissertations from 1981

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Human Pharmacokinetics of 5-Formyl Tetrahydrofolate, Bruce Kenneth Birmingham

Theses/Dissertations from 1980

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EFFECTS OF LIQUID MEMBRANES ON GASTROINTESTINAL ABSORPTION OF DRUGS IN RATS, Alan Paul Agins

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ACETYLATION OF THE CHOLINE ANALOG HOMOCHOLINE BY MEMBRANE BOUND CHOLINE-0-ACETYLTRANSFERASE IN MOUSE FOREBRAIN, Christina G. Benishin

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A MECHANISM OF ACTION OF GOLD IN RHEUMATOID ARTHRITIS. A BIOCHEMICAL AND MORPHOLOGICAL INVESTIGATION OF THE DIRECT EFFECT OF GOLD SODIUM THIOMALATE (GST) ON HUMAN SYNOVIAL CELLS IN CULTURE, Ronald Lee Goldberg

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RADIOIMMUNOASSAY OF TESTOSTERONE AND ESTROGENS IN BLOODSTAINS FOR THE PURPOSE OF SEX IDENTIFICATION, Dennis Charles Hilliard

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DEVELOPMENT OF A MAMMALIAN COLLAGENASE ASSAY USING A SOLUBLE SUBSTRATE, Nancy A. LaPosta-Frazier

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A STUDY OF THE DISCRIMINATIVE STIMULUS PROPERTIES AND SOME ANALGESIC PROPERTIES OF THE NARCOTIC AGONIST-ANTAGONIST CYCLAZOCINE, Michael D. McCarten

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A STUDY ON THE ABILITY OF PRECURSOR AND ACETYLATED PRODUCT TO REFILL CHOLINERGIC VESICLES INDEPENDENTLY OF THE CYTOPLASM, Stephen Harold Nelson

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THE ANXIOMIMETIC PROPERTIES OF PENTYLENETETRAZOL IN THE RAT, Gary Terence Shearman

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CHARACTERIZATION OF THE FIBROTIC LESION IN DIBUTYLTIN-INDUCED EXPERIMENTAL LIVER INJURY, Jeannee Karen Yermakoff

Theses/Dissertations from 1979

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CELL PROLIFERATION AND COLLAGEN SYNTHESIS IN EXPLANT CULTURES OF ARTERIOSCLEROTIC RABBIT AORTA, Douglas Otto Fisher

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A COMPARISON BETWEEN THE SELF-ADMINISTRATION OF CLONIDINE AND FENTANYL, Gary Terence Shearman

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A COMPARISON OF SOLUBILIZED AND MEMBRANE BOUND FORMS OF CHOLINE-O-ACETYLTRANSFERASE IN MOUSE BRAIN NERVE ENDINGS, Craig Paul Smith

Theses/Dissertations from 1978

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DEVELOPMENT OF A FLUORESCENT ASSAY FOR COLLAGENHETEROGENEITY USING MDPF-SDS-PAGE, Ronald Lee Goldberg

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THE TOXICITY OF PARATHION TO ORCONECTES RUSTICUS AND VIVIPARUS MALLEATUS, Leslie Alan Goldsmith

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EFFECTIVENESS OF BUTYROPHENONES AND RELATED DRUGS IN NARCOTIC WITHDRAWAL IN THE RAT, Martin Dennis Hynes III

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INVESTIGATION OF THE EFFECTS OF SECOBARBITAL ON COGNITIVE AND PSYCHOMOTOR SKILLS RELATED TO DRIVING AN AUTOMOBILE, Robert Arthur Miller

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TRICYCLIC ANTIDEPRESSANTS AS UPTAKE BLOCKERS, Girolamo A. Ortolano

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AN EXPERIMENTAL MODEL OF HEPATIC FIBROSIS INDUCED BY THE ADMINISTRATION OF DIBUTYLTIN DICHLORIDE, Jeannee Karen Yermakoff

Theses/Dissertations from 1977

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STUDIES ON THE REGULATION OF PROLYL HYDROXYLASE, Clinton Oscar Chichester

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EFFECT OF CONDITIONAL STIMULUS ON MORPHINE WITHDRAWAL SIGNS IN THE RAT, Richard B. Drawbaugh

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THE EFFECT OF CAFFEINE ON CARDIAC VULNERABILITY TO TACHYARRHYTHMIA IN THE RAT, Fred A. Rotenberg

Theses/Dissertations from 1976

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Effect of Continuous Inhalation of Ethanol Vapors in the Rat, Steven W. Mann

Theses/Dissertations from 1975

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MECHANISM AND CHARACTERISTICS OF DRUG-INDUCED AGGRESSION, Gerald Gianutsos

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Pharmacological Evaluation of an Asterosaponin Extract from Asterias Forbesi (Desor), Leslie Alan Goldsmith

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Interaction Between Nigro-Striatal Lesions and Drugs Affecting Dopamine Receptors, Martin Dennis Hynes

Theses/Dissertations from 1974

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Quinoxaline 1, 4-Dioxides. A Mechanistic Study of Their Formation and the Structural Assignment of 6(7) Isomeric Products, Nicholas D. Alteri Jr.

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Effect of Selected Drugs on Control of Morphine Withdrawal Hypothermia Induced by Morphine or Conditional Stimulus Associated with Morphine, Richard B. Drawbaugh

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Operant Analysis of Behavior Associated With Oral Self-Administration Of Drug Solutions in Rats, Joseph David Zabik

Theses/Dissertations from 1973

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An Investigation of the Relationship Between the Sulfhydryl Activity and the Toxicity of a Series of Vinyl Sulfone Molluscicidal Agents, Paul Thomas La Rocca

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Pharmacological Evaluation of an Extract from Eisenia Bicyclis, David Michael Whitaker

Theses/Dissertations from 1972

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Thermodynamics and Molecular Orbital Calculations for the Parabens, Kenneth S. Alexander

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Brain Sensitivity to Barbiturates and Brain Gamma-Aminobutyric Acid, Girish J. Patel

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GLYOXAL AND ESTRADIOL MEDIATED ALTERATIONS IN RAT UTERINE HISTONE ACETYLATION, Robert Louis Procaccini

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PARGYLINE, SUCCINIC ACID AND L-ASCORBIC ACID AS PROTECTIVE AGENTS AGAINST HYPERBARIC OXYGEN TOXICITY: POSSIBLE INVOLVEMENT OF ALTERED GAMMA-AMINOBUTYRIC ACID AND AMMONIA METABOLISM, Robert Alfred Schatz

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The Effect of Modifiers of Microsomal Electron Transport On Carbon Tetrachloride Hepatoxicity, Kenneth Alfred Suarez

Theses/Dissertations from 1971

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THERMODYNAMlCS OF SULFONAMIDE SOLUTIONS, John W. Mauger

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LIVER ENLARGEMENT AND THE MODIFICATION OF HEPATIC MICROSOMAL DRUG METABOLISM BY PYRETHRUM, Angela Caretta Springfield

Theses/Dissertations from 1970

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Effect of Acute Hypoxia or Chronic Social Isolation on Brain Sensitivity and Barbiturate Metabolism, Irwin Paul Baumel

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Alteration of Proline Hydroxylase Activity by Corticosteroids, Kenneth Robert Cutroneo

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The Modification of Hepatic Microsomal Drug Metabolism by Phenobarbital and D-Amphetamine, Robert Thomas Louis-Ferdinand

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The Solubility of Amino Acids in Various Solvent Systems, Thomas E. Needham

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Learning Associated with the Amphetamine-State: Role of Brain Amines, Mark Roffman

Theses/Dissertations from 1969

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The Solubility of Several Barbituric Acid Derivatives in Hydroalcoholic Mixtures, Thomas L. Breon

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Investigation of the Role of Dopamine in Maintenance of Arterial Hypertension, Harold Llewellyn Crossley

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Characterization of the Effect of Methylchloroform Inhalation on Hepatic Drug Metabolism in the Rat, Arnold Merwin Olshan

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Pharmacology of Some 1-Alkyl-3-Benzoylpyridinium Halides, Angela Caretta Springfield

Theses/Dissertations from 1968

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Differential Effects of Guanethidine and Reserpine on Norepinephrine in the Brain and Heart of Male Albino Rats Subjected to Restraint, Thomas Paul Blaszkowski

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The Relationship of Dopamine to Blood Pressure in Experimental Renal Hypertension, David William Coates

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An Investigation of the Relationship Between the Sulfhydryl Reactivity and the Inhibition of In Vitro Oxygen Uptake By Certain Molluscicidal B-Nitrostyrene Derivatives, Robert Thomas Louis-Ferdinand

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A Mathematical Analysis of an Irreversible Consecutive First Order Reaction Using Hydrocortisone Sodium Succinate as a Model, John W. Mauger

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A Preliminary Study of the Effects of an Imidazolecarboxyhydrazide on Blood Pressure, Monoamine Oxidase, and Locomotor Activity, Robert Louis Procaccini

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Effects of Colloidal Silica on the Apparent Viscosity of White Petrolatum, Louis Gedeon Roy

Theses/Dissertations from 1967

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Ultransonic Degradation of Aspirin in Mixed Solvent Systems, Thomas E. Needham

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The Effects of Monoamine Oxidase Inhibitors Upon Urinary Excretion of Dopamine and Changes in Arterial Blood Pressure, Charles Martin Vacca

Theses/Dissertations from 1966

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Comparative Effects of Certain Derivatives of Cyclohexanol, Sonia Margarita Gerena

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Toxicology of Muconomycins A and B: Inflammatory Properties of Two New Antibiotics: Electrolyte and Protein Characterization of Inflammatory Exudate and Production of a Model State of Ascites in Male Albino Rats, Anthony Michael Guarino

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The Comparative Cardio-Inhibitory Effects of Certain Cyclohexanol and Cyclohexylamine Derivatives, David Charles Kosegarten

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Some Pharmacological Properties of Trimethoxy Analogs of Pheniramine, Tripelennamine, and Diphenhydramine, Ronald Otto Langner

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The Effects of Selected Variables on the Microencapsulation of Solids, Louis A. Luzzi

Theses/Dissertations from 1965

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INHIBITION OF ACETYLCHOLINESTERASE BY COPPER CHELATES, Ernest Mario

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The Effects of Chronic Thyroxine and Pargyline Treatment on Locomotor Activity, Blood Pressure, Urinary Electrolytes, Body Weight and Liver and Brain Monoamine Oxidase Activity in Male Albino Rats Maintained on Fixed Caloric Input, Angelo Benedict Mendillo III

Theses/Dissertations from 1963

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Effect of the Trimethoxy Group, Young Soo Choi

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The Effect of Thyroid and MO911 on Locomotor Activity and Monoamine Oxidase Activity in Mice, Vincent Eugene Reid