URI Department of Biomedical and Pharmaceutical Sciences Department Theses and Dissertations | Biomedical and Pharmaceutical Sciences | University of Rhode Island
 
Explore master's theses and doctoral dissertations from graduates of the URI Department of Biomedical and Pharmaceutical Sciences.

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Theses/Dissertations from 2016

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Bile Acids and Premature Labor in Intrahepatic Cholestasis of Pregnancy, Sangmin You

Theses/Dissertations from 2015

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A Cross-Sectional Analysis of Bronchodilator Prescribing in COPD and Cardiovascular Comorbidity, Damilola Tejumola Adesanoye

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NRF as an Oxidative Stress and Nutrient Responsive Transcription Factor in Calorie Restriction, Laura Armstrong

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Synthesis of 2-Amino-α-Carboline and Analogues Relevant for Structural Investigations of the Corresponding DNA Adducts, Matthew S. Blake

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Tolfenamic Acid: A Potential Modifier of Tau Protein in Alzheimer's Disease, Joanna K. Chang

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CHEMICAL INVESTIGATION OF CANDIDATE PROBIOTICS IN AQUACULTURE AND FORMULATION OF A PROBIOTIC AGENT FOR OYSTER LARVICULURE, Christine Anh Dao

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Therapeutic Drug Monitoring of Immunosuppresive, Mwlod A. Ghareeb

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Effects of intensified care management activities and diabetes medication copayment reduction on medication adherence and health care costs, Kyungwan Hong

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DEVELOPMENT OF COPPER SULFIDE NANOPARTICLES FOR PHOTOTHERMAL AND CHEMO THERAPY OF CANCER CELLS, Yajuan Li

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EVALUATION OF IN VITRO ANTI-INFLAMMATORY, ANTI-DIABETIC AND ANTI-LIPOGENIC ACTIVITY OF NATURAL POLYPHENOLIC EXTRACTS AND THEIR PURE CONSTITUENTS, Pragati P. Nahar

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EFFECTS OF PERFLUORINATED COMPOUNDS (PFCs) ON METABOLIC TISSUES AND THE BENEFITS OF CALORIC RESTRICTION, Deanna M. Salter

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Role of Nuclear Factor E2 Related Factor 2 (Nrf2) in Environmental Chemical Induced Steatosis and Adipogenesis, Prajakta Shimpi

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GARCINIA KOLA: PHYTOCHEMICAL, BIOLOGICAL AND FORMULATION STUDIES, Yasah Vezele

Theses/Dissertations from 2014

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EFFECT OF HOSPITALIZATION ON THE INTEGRITY OF THE MEDICATION REGIMEN IN PATIENTS WITH DIABETES MELLITUS, Matthew J. Alcusky

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MOLECULAR INTERACTION IN CARBOXYLESTERASES-BASED CATALYSIS: ONTOGENIC EXPRESSION AND INDUCTION THROUGH A NOVEL ELEMENT, Yi-Tzai Chen

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MEASURING AND PREDICTING THE FACTORS ASSOCIATED WITH PERSISTENCE TO ANTIDEPRESSANT THERAPY IN PATIENTS WITH DIABETES, Harini Chinthapatla

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FACTORS ASSOCIATED WITH SUBOPTIMAL SAFETY LABORATORY OF METFORMIN THERAPY, Yu Seon Jung

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PHYTOCHEMICAL INVESTIGATION OF THE TRADITIONAL BOTANICAL MEDICINE IRESINE CELOSIA, Caroline Grace Killian

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PHYTOCHEMICAL AND BIOLOGICAL INVESTIGATION OF GALLOTANNINS FROM RED MAPLE (ACER RUBRUM) SPECIES, Hang Ma

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LIPOSOMES FOR THE CONTROLLED DELIVERY OF MULTIPLE DRUGS, Swapnil A. Malekar

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THE EVALUATION OF DOCTOR OF PHYSICALTHERAPY STUDENTS’ CONFIDENCE AND SATISFACTION USING HUMAN PATIENT SIMULATION, Brooke O'Connell

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COMPARTMENTALIZED D2-DOPAMINE RECEPTORS: ROLES IN SIGNALING & POTENTIAL MECHANISM OF ANTIPSYCHOTIC DRUG ACTION, J. Christopher Octeau

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AMPHIPHILIC CYCLIC CELL-PENETRATING PEPTIDES AS DRUG DELIVERY VEHICLES AND ANTIMICROBIAL PEPTIDES, Donghood Oh

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DESIGN AND EVALUATION OF 5′-O-DICARBOXYLIC AND POLYARGININE FATTY ACYL DERIVATIVES OF ANTI-HIV NUCLEOSIDES, Bhanu Priya Pemmaraju Venkata

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EVALUATING THE ROLE OF HYPOGLYCEMIA & COMORBID ILLNESS ON DIABETES MANAGEMENT BEHAVIORS, Saumitra Vijay Rege

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SYNTHESIS AND EVALUATION OF AMPHIPHILIC PEPTIDES AS NANOSTRUCTURES AND DRUG DELIVERY TOOLS, Naser Ali Sayeh

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EPIGENETIC MODIFICATION AND ANALYSIS OF NATURAL PRODUCT GENE CLUSTERS TO ENHANCE DRUG DISCOVERY FROM BACTERIA, Justin D. Schumacher

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TRANSCRIPTIONAL REGULATION OF ALDO-KETO REDUCTASE 1D1, Leila Valanejad

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CADMIUM PROMOTES PROLIFERATION OF TRIPLE-NEGATIVE BREAST CANCER CELLS THROUGH EGFR-MEDIATED CELL CYCLE REGULATION, Zhengxi Wei

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STRUCTURAL AND CONFORMATIONAL INSIGHTS INTO BULKY ARYLAMINE-INDUCED MUTAGENESIS, Lifang Xu

Theses/Dissertations from 2013

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Pharmacodynamic Mechanisms of Tolfenamic Acid Induced SP1 Degradation Relative to Alzheimer's Disease Pathology, Lina I. Adwan

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Applying QbD and Pat in Biological Manufacturing for “Continued Process Verification”, Prakash Bedre

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Trends in the Use of Preventive Care by Women in the U. S. General Population, Erin Bennett

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Associations Between Patient Characteristics and Utilization in a Commercial Schizophrenia Population, Thomas Joseph Bunz

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Phytochemicals from the Roots of Northern Highbush Blueberry (Vaccinium Corymbosum), Amanda Cirello

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Effect of Metabolic Disease and Xenobiotic Exposure on Hepatic ATP-Binding Cassette (ABC) Drug Transporter Expression, Ajay Chowdary Donepudi

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Sequence Effects on the Repair and Replication of Arylamine-DNA Adducts, Vipin Jain

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Predictors of Non-Vaccination Against Human Papillamovarius Among Us Women Aged 18-26, H. Elsa Larson

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Prediction of Heptatic and Renal Clearance in Pediatric Populations: A "Bottom-Up" Approach Versus "Top-Down" Recognition of Covariates, Hong Lu

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Model-Based Approaches to Characterize Clinical Pharmacokinetics of Atorvastatin and Rosuvastatin in Disease State, Joyce Macwan

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Role of Nuclear Factor E2 Related Factor 2 (NRF2) in Development of Steatosis and Drug Transporter Alterations, Vijay RS More

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Cyclic Peptides: Design, Characterization, Self-Assembly, and Applications as Nano Drug Delivery Systems, Amir Nasrolahi Shirazi

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Use and Unintended Consequences of Antidepressant Medications by Depressed Older Adults, Eun Sun Noh

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Compounds from A. Platanoides Bark, V. Corymbosum Roots & Topical Formulations using Maple Syrup, Raed Omar

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Structural and Conformational Probing of 2-Acetylaminofluorene-Modified -1, -2 and -3 Slipped Mutagenic Intermediates, Anusha Sandineni

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Producing In-Situ Nanoparticles of Griseofulvin using Supercritical Antisolvent Methodology, Pratik Sheth

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Effect of Manufacturing Methods Used in the Stability of Amorphous Solid Solutions and Predictions to Test them, Kaoru Tominaga

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Suppression of PXR Expression by Endoplasmic Reticulum Stress and Microrna, Thaveechai Vachirayonstien

Theses/Dissertations from 2012

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NRF2 AS A NUTRIENT SENSITIVE TRANSCRIPTION FACTOR, Supriya Kulkarni

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Brain Penetration of Tolfenamic Acid and its Ability to Enhance the Cognitive Functions and to Lower Amyloid Pathology in Animal Models of Alzheimer's Disease, Gehad Mohammed Subaiea

Theses/Dissertations from 2011

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THE FORMULATION OF NATURALLY OCCURING POLYPHENOLIC NUTRACEUTICAL AGENTS USING HOT-MELT EXTRUSION, Aditya Duvuri

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BIOFILM PRODUCTION BY CLINICAL STAPHYLOCOCCUS AUREUS AND ITS INHIBITION BY HYPERICUM METABOLITES, Simon Antranik Sarkisian

Theses/Dissertations from 2010

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Drug Safety Issues Focusing on Liver and Pancreas Toxicity, Thamir M. Alshammari

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Farnesoid X Receptor Modulation by Systematic Ligands of Translocator Protein (18KDA), Linnea Elsa Anderson

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Evaluation of treatment discontinuation, patterns of respiratory arrest and myocardial infarction and re-hospitalization rates in patients treated for schizophrenia, Gillis Joseph Carrigan

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Lead Exposure, Aging and Biomarkers in Alzheimer's Disease, Aderemi Dosunmu

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Amorphous solid solutions using hot melt extrusion, Ashish Sarode

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Evaluation of treatment patterns for medications utilized in the management of pediatric attention-deficit/hyperactivity disorder, Jason Charles Simeone

Theses/Dissertations from 2009

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Methicillin-resistant Staphylococcus aureus: Pharmacoepidemiologic assessment of common medications, Aisling R. Caffrey

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Evaluation of mixed-effects modeling techniques for the analysis of longitudinal data collected from PK-PD and efficacy clinical trials, Rajesh Narwal

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Solubility and permeability enhancement of levothyroxine sodium for oral administration, Dimple Pabla

Theses/Dissertations from 2008

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Tolfenamic Acid Interrupts the De Novo Synthesis of Plaque-Forming Amyloid Beta Peptides: Implications for Alzheimers Disease, Lina I. Adwan

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The Formulation and Process Development of a Novel Multiparticulate Extended Release Pharmaceutical Delivery Platform for a Highly Water Soluble Compound, Cyrus D. Agarabi

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In Vitro Effects of Emollient Substances on Release of Ketorolac Tromethamine, Burcak Alioglu

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To treat or not to treat: The role of antibiotics in the management of community-acquired respiratory tract infections in an ambulatory setting, Julie Ann Deangelis

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Chemistry of antibiotics from Atlantic Actinomycete and Bacillus bacteria, Aaron Martin Socha

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Investigation of the release of carbamazepine from polyvinyl pyrrolidone matrices processed using near-critical and super critical carbon dioxide, Shweta Ugaonkar

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Applications of linear and cyclic peptides as enzyme inhibitors and molecular transporters, Guofeng Ye

Theses/Dissertations from 2007

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Solid-state plasticizers for melt extrusion, Dipen Desai

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Strategies for the optimization of immunotherapy in kidney transplantation, Anisha E. Mendonza

Theses/Dissertations from 2006

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Identification and Minimization of Protein Loss During the Manufacturing of a Beta Domain Deleted Recombinant Human Factor VIII, Cyrus Agarabi

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Effects of endocrine-disrupting chemicals on fish reproduction and reproductive indicators, Lesley Judith Mills

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Evaluation of potential multi-particulate drug delivery systems, Aruna Mummini Murty

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The pharmacokinetics and pharmacodynamics of mycophenolic acid in kidney transplant recipients, Chirag G. Patel

Theses/Dissertations from 2005

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Identification of Oct-2 as a mediator of lead neurotoxicity, Saleh Abdulrahman Bakheet

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Effectiveness of recipient restriction programs in Medicaid managed care organizations, Jason Michael Beaubien

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The relationship between articular cartilage damage and lubricin integrity following injury and in inflammatory arthritis, Khaled Ahmed Elsaid

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Validation of a tool to measure drug knowledge: Evaluating bioterrorism preparedness activities, Gregory A. Low

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A descriptive study of beta2-agonist use in asthma patients based on a nationally representative sample, James Melfi

Theses/Dissertations from 2004

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POPULATION PHARMACOKINETICS OF CYCLOSPORINE IN HEART AND LUNG TRANSPLANT PATIENTS, Gautam Baheti

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Self-reported medication adherence among patients with diabetes, Zlata Cerimagic

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Evaluation of hot-melt extrusion technology to improve dissolution rates of poorly water soluble drugs, Rina Chokshi

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Isolation of marine metabolites from Symbiodinium species of dinoflagellates, Katherine Evelyn Drainville-Higgins

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USING PHARMACY CLAIMS DATA TO EVALUATE ADHERENCE AND PERSISTENCE WITH PRESCRIBED MEDICATIONS IN PATIENTS WITH DIABETES MELLITUS, Pamela J. Johnson

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ENHANCEMENT OF CARBAMZEPINE SOLUBILITY USING SELECTED WATER SOLUBLE POLYMERS AND A SOLID DISPERSION TECHNIQUE, Sameer Late

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BIOACTIVE SECONDARY METABOLITES PRODUCED BY MARINE MICROORGANISMS: THEIR ISOLATION, STRUCTURAL ELUCIDATION AND FUNCTION, Jiayuan Liu

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A MECHANISTIC STUDY TO IDENTIFY PHYSICALLY STABLE AMORPHOUS SOLID DISPERSION, Madhav Vasanthavada

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Preparation of optically pure anti-diolepoxides of 2-fluorobenzo[a]-pyrene and their DNA adducts, Tianle Yang

Theses/Dissertations from 2003

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Drug Benefit Plans for Elderly Under Managed Care and Utilization of Lipid Lowering Agents, Susan M. Abughosh

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Using the Medical Expenditure Panel Survey (MEPS) to Assess Antibiotic Utilization in Acute Respiratory Tract Infections, Muhammed S. Al-Sultan

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QUANTIFICATION OF INJECTABILITY OF A NEW SELF-ADMINISTERED INTRAMUSCULAR INJECTION, Roja Anandakumar

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Type II collagen differentially degraded epitopes can be used to monitor in vitro and in vivo cartilage degradation, Brian Roland Felice

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EXAMPLES OF POPULATION PHARMACOKINETIC MODELING IN DRUG DEVELOPMENT USING NONMEM, Julie M. Jones

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HEALTH-RELATED QUALITY OF LIFE AS PREDICTOR OF ADHERENCE WITH ANTIRETROVIRAL MEDICATION, Rakesh Joshi

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THE DEC1 TRANSCRIPTION FACTOR: ONCOGENIC INVOLVEMENT AND MOLECULAR MECHANISMS ON TRANSCRIPTION REGULATION, Yuxin Li

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COPING WITH HUMAN IMMUNODEFICIENCY DISEASE AS PREDICTOR OF ADHERENCE WITH ANTIRETROVIRAL MEDICATION, Saurabh Mistry

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TRAZODONE HYDROCHLORIDE CONTROLLED RELEASEMATRIX AND MATRIX-MINI TABLETS, Kiran Penumatcha

Theses/Dissertations from 2002

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Rational Approaches to the Regulation of Nonprescription Medicines, Anand S. Achanta

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MECHANISTIC STUDIES TO ELUCIDATE THE ROLE OF LIPID VEHICLES ON SOLUBILITY, FORMULATION AND BIOA VAILABILITY OF POORLY SOLUBLE COMPOUNDS, Inayet Dumanli

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Mechanistic studies to elucidate the role of lipid vehicles on solubility, formulation and bioavailability of poorly soluble compounds, Inayet Dumanli