Psychosis in a 12-year-old HIV-positive girl with an increased serum concentration of efavirenz
Document Type
Article
Date of Original Version
11-15-2007
Abstract
Clearance and adverse effects of efavirenz are associated with CYP2B6-G516T polymorphism. Little is known about the prevalence of genotypes and implications for screening in children. We report (to our knowledge, for the first time in a child) the emergence of psychosis in a 12-year old white girl with an increased efavirenz concentration and heterozygous gene polymorphism of the CYP2B6-G516T. © 2007 by the Infectious Diseases Society of America. All rights reserved.
Publication Title, e.g., Journal
Clinical Infectious Diseases
Volume
45
Issue
10
Citation/Publisher Attribution
Lowenhaupt, Elizabeth A., Matson, Bushra Qureishi, Akihiko Saitoh, and David Pugatch. "Psychosis in a 12-year-old HIV-positive girl with an increased serum concentration of efavirenz." Clinical Infectious Diseases 45, 10 (2007). doi: 10.1086/522764.