Nonmalignant Pain Symptom Subgroups in Nursing Home Residents

Christine M. Ulbricht, University of Massachusetts Chan Medical School
Jacob N. Hunnicutt, University of Massachusetts Chan Medical School
Giovanni Gambassi, Università Cattolica del Sacro Cuore, Campus di Roma
Anne L. Hume, College of Pharmacy
Kate L. Lapane, University of Massachusetts Chan Medical School

Abstract

Context: Despite many nursing home residents experiencing pain, research about the multidimensional nature of nonmalignant pain in these residents is scant. Objectives: To identify and describe pain symptom subgroups and to evaluate whether subgroups differed by sex. Methods: Using Minimum Data Set 3.0 data (2011-2012), we identified newly admitted nursing home residents reporting pain (n = 119,379). A latent class analysis included 13 indicators: markers for pain (i.e., severity, frequency, impacts sleep, and function) and depressive symptoms. Sex was evaluated as a grouping variable. Multinomial logistic models identified the association between latent class membership and covariates, including age and cognitive impairment. Results: Four latent subgroups were identified: severe (15.2%), moderate frequent (26.4%), moderate occasional with depressive symptoms (26.4%), and moderate occasional without depressive symptoms (32.0%). Measurement invariance by sex was ruled out. Depressed mood, sleep disturbances, and fatigue distinguished subgroups. Age ≥75 years was inversely associated with belonging to the severe, moderate frequent, or moderate occasional with depressive symptoms subgroups. Residents with severe cognitive impairment had reduced odds of membership in the severe pain subgroup (adjusted odds ratio [aOR]: 0.84; 95% confidence interval [CI]: 0.78-0.90) and moderate frequent pain subgroup (aOR: 0.60; 95% CI: 0.56-0.64) but increased odds in the moderate occasional pain with depressive symptoms subgroup (aOR: 1.12; 95% CI: 1.06-1.18). Conclusion: Identifying subgroups of residents with different patterns of pain and depressive symptoms highlights the need to consider physical and psychological components of pain. Expanding knowledge about pain symptom subgroups may provide a promising avenue to improve pain management in nursing home residents.