Effects of CPTA upon carotenogenesis and lipoidal constituents in Rhodotorula species

Authors

Ernest Hayman, University of Rhode Island
O. Chichester, University of Rhode Island
Kenneth L. Simpson, University of Rhode Island

Document Type

Article

Date of Original Version

1-1-1974

Abstract

The effects of 2-(4-chlorophenyl)-triethylamine (CPTA) upon carotenogenesis in Rhodotorula glutinis, and upon various lipoidal constituents of R. rubra were studied. CPTA was found to cause the accumulation of lycopene and γ-carotene and to inhibit the formation of fatty acids and ergosterol. Upon removal of the inhibitor lycopene was metabolized to the cyclic carotenes and the levels of ergosterol increased. It was proposed that CPTA inhibits the cyclase enzyme of carotenogenesis, inhibits the formation of ergosterol, and causes the build-up of intermediates of these compounds. © 1974.

Publication Title, e.g., Journal

Phytochemistry

Volume

13

Issue

7

Citation/Publisher Attribution

Hayman, Ernest, O. Chichester, and Kenneth L. Simpson. "Effects of CPTA upon carotenogenesis and lipoidal constituents in Rhodotorula species." Phytochemistry 13, 7 (1974): 1123-1127. doi: 10.1016/0031-9422(74)80085-3.