Oncogenicity of plaque variants of celo virus in newborn hamsters
Document Type
Article
Date of Original Version
1-1-1973
Abstract
Small-plaque (SP) and large-plaque (LP) variants of chicken-embryo-lethal-orphan (CELO) virus, an avian adenovirus, were tumorigenic in newborn hamsters inoculated either subcutaneously (sc) or intraperitoneally (ip). Tumors were induced at the site of sc inoculation. With the ip route, tumors were induced in the peritoneal cavity and liver. No significant difference was observed either in thelatent period of induction or in tumor incidence between the two virus variants. The neoplasms induced insubcutaneous areas and in the peritoneal cavity were classified histologically as anaplastic sarcomas;the liver tumors were bile-duct carcinomas. The sera from the SP and LP tumor-bearing hamsters containedCELO-specific T antibodies.—J Natl Cancer Inst 50:791-795, 1973. © 1973 OUP Publishing Ltd.
Publication Title, e.g., Journal
Journal of the National Cancer Institute
Volume
50
Issue
3
Citation/Publisher Attribution
Pendola, R. G., V. J. Yates, R. E. Wolke, and V. Jasty. "Oncogenicity of plaque variants of celo virus in newborn hamsters." Journal of the National Cancer Institute 50, 3 (1973). doi: 10.1093/jnci/50.3.791.