Seasonal influence on phenolic-mediated antihyperglycemic properties of Canadian sugar and red maple leaves using in vitro assay models
Document Type
Article
Date of Original Version
6-1-2012
Abstract
Red and sugar maple leaves collected in the summer and fall from Canada, were evaluated for phenolic content, antioxidant, α-glucosidase, and α-amylase inhibitory activities variation. The phenolic contents of summer red maple leaves (RML-S) and summer sugar maple leaves (SML-S) were higher than red and sugar maple leaves collected in fall (RML-F and SML-F, respectively). HPLC analyses showed differences in phenolic compounds present in the SML samples compared to the RML samples. The extracts were assayed for yeast and rat α-glucosidase inhibitory activities. Both results showed that SML-S extracts had the highest inhibitory activity which could possibly be attributed to the unique phenolics present therein. Milder effects were observed in terms of α-amylase inhibitory activity, with RML-F having the highest inhibitory activity. These results suggest that maple tree leaf extracts may have potential for phenolic-mediated α-glucosidase inhibition, relevant to type 2 diabetes management, with SML-S extract having the highest bioactivity.
Publication Title, e.g., Journal
Food Science and Biotechnology
Volume
21
Issue
3
Citation/Publisher Attribution
Apostolidis, Emmanouil, Liya Li, Bouhee Kang, Chong M. Lee, and Navindra P. P. Seeram. "Seasonal influence on phenolic-mediated antihyperglycemic properties of Canadian sugar and red maple leaves using in vitro assay models." Food Science and Biotechnology 21, 3 (2012). doi: 10.1007/s10068-012-0098-x.