Characterization and tissue distribution of pyruvate carboxylase in atlantic salmon (Salmo salar)

Document Type

Article

Date of Original Version

1-1-1993

Abstract

1. 1. The mitochondrial fraction of liver from Atlantic salmon contained about 90% of subcellular pyruvate carboxylase activity (EC 6.4.1.1). 2. 2. Kidney, brain, heart, and gills contained 20, 19, 3 and 2%, respectively, of the activity observed per unit weight of liver. 3. 3. Assays with partially purified enzyme showed the level of acetyl CoA and the ratio of ATP/ADP to be the major regulators, with ADP (but not AMP) being a potent inhibitor of ATP binding. © 1993.

Publication Title, e.g., Journal

Comparative Biochemistry and Physiology -- Part B: Biochemistry and

Volume

106

Issue

3

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