Sensor integration of multiple tripolar concentric ring electrodes improves pentylenetetrazole-induced seizure onset detection in rats
Document Type
Conference Proceeding
Date of Original Version
12-14-2012
Abstract
As epilepsy affects approximately one percent of the world population, electrical stimulation of the brain has recently shown potential for additive seizure control therapy. Previously, we applied noninvasive transcranial focal stimulation via tripolar concentric ring electrodes on the scalp of rats after inducing seizures with pentylenetetrazole. We developed a system to detect seizures and automatically trigger the stimulation and evaluated the system on the electrographic activity from rats. In this preliminary study we propose and validate a novel seizure onset detection algorithm based on exponentially embedded family. Unlike the previously proposed approach it integrates the data from multiple electrodes allowing an improvement of the detector performance. © 2012 IEEE.
Publication Title, e.g., Journal
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Citation/Publisher Attribution
Makeyev, Oleksandr, Quan Ding, Steven M. Kay, and Walter G. Besio. "Sensor integration of multiple tripolar concentric ring electrodes improves pentylenetetrazole-induced seizure onset detection in rats." Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (2012): 5154-5157. doi: 10.1109/EMBC.2012.6347154.