Explore master's theses and doctoral dissertations from graduates of the URI Department of Cell and Molecular Biology.

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Theses/Dissertations from 2024

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INVESTIGATION OF FANCD2 FUNCTION UTILIZING A MULTI-OMIC APPROACH, Justin Blaize

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ALTERED TRANSCRIPTIONAL REGULATION IS AN EARLY DRIVER OF DISEASE IN AN IN VITRO MODEL OF C9ORF72 ALS/FTD, Michelle Jean Gregoire

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DEFINING THE PEPTIDYL TRANSFERASE ACTIVE SITE OF THE RIBOSOME, Erin Killeavy

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IDENTIFICATION OF CELLULOSE SYNTHASE STRUCTURAL FEATURES INVOLVED IN CELLULOSE SYNTHESIS COMPLEX FORMATION, Jamie Lamkin

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INVESTIGATING A MAJOR 16S rRNA FOLDING EVENT IN THE ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT, Brenna Levesque

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APPLYING COMMUNITY ECOLOGY PRINCIPLES TO ASSESS IMPACTS OF THE HARMFUL ALGAL GENUS, PSEUDO-NITZSCHIA, ON MARINE BACTERIOPLANKTON AND SCIENCE COMMUNICATION CHALLENGES, Julie Maurer

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INVESTIGATION OF SERUM RESISTANCE IN HAEMOPHILUS PARAINFLUENZAE, Morgan J. McPartland

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INVESTIGATING THE ROLE OF FANCD2 IN NEUROGENESIS, Bahaa M. Noori

Theses/Dissertations from 2023

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ANTIBIOTIC TOLERANCE IN QUIESCENT UROPATHOGENIC ESCHERICHIA COLI, Daniel Alexander Banas

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DEFINING THE ESSENTIAL GENOME OF HAEMOPHILUS PARAINFLUENZAE AND CONDITIONALLY ESSENTIAL GENES REQUIRED FOR ITS SURVIVAL IN BIOFILMS AND SERUM COMPLEMENT, Thaís Harder de Palma

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BIOCHEMICAL AND GENETIC MECHANISMS UNDERPINNING ESCHERICHIA COLI CELL CYCLE AND GROWTH TRANSITIONS, Josiah Morrison

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Cell Stress, protein quality control, and activation of toxin antitoxin systems in Escherichia coli, Benjamin Piraino

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EXAMINING THE REGULATION OF THE BS21 HOMOLOGS IN FRANCISELLA TULARENSIS, Sierra Schmidt

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Heterogeneous ribosomes and bS21: An investigation of impacts and mechanisms of altered translation in Francisella tularensis, Hannah Trautmann

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DEVELOPMENT OF TARGETED DRUG COMBINATIONS BLOCKING MULTI-DRIVER ONCOGENESIS, Alexander Yonchak

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CALDICELLULOSIRUPTOR BESCII GENOME-SCALE METABOLIC MODEL SERVES AS A PLATFORM TO REVEAL THE STRATEGIES TO INCREASE ETHANOL AND 2,3-BUTANEDIOL PRODUCTION, Ke Zhang

Theses/Dissertations from 2022

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INVESTIGATING THE ROLE CORYNEBACTERIUM MATRUCHOTII HAS WITHIN SUPRAGINGIVAL PLAQUE SPATIAL ORGANIZATION AND ITS RESPONSE TO ORAL STREPTOCOCCI AND SALIVA, Eric Ganeto Almeida

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Seasonal hypoxia impacts nutrient fluxes and microbial communities in Narragansett Bay sediments, Katherine Elizabeth Bell

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UNDERSTANDING THE ROLES OF HETEROGENOUS SWI/SNF COMPLEXES IN REGULATION OF DIFFERENTIAL GENE EXPRESSION, Tomali Chakravarty

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BACTERIAL COMMUNITY DYNAMICS IN RHODE ISLAND COASTAL ECOSYSTEMS, Zachary Pimentel

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DECIPHERING BIOGENIC SILICA PRODUCTION TRENDS IN PICOPLANKTON OF THE SUBARCTIC NORTH PACIFIC USING NOVEL DNA BARCODING METHODS, Andrew Presley

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PROBIOTICS FOR EASTERN OYSTER HATCHERIES: COMMERCIAL FORMULATIONS AND EFFECT ON MICROBIAL COMMUNITIES, Evelyn Takyi

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REGULATION OF COMPOSITION AND FUNCTIONS OF SWI/SNF CHROMATIN REMODELING COMPLEX, Kathleen Diep Tran

Theses/Dissertations from 2021

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VIBRIO CORALLIILYTICUS RE22 TYPE VI SECRETION SYSTEMS CONTRIBUTE TO TEMPERATE CORAL LYSIS AND ENDOSYMBIONT DEATH, Nathaniel Awkerman

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TRANSCRIPTIONAL REGULATION OF SOX5 AND WWOX BY FANCD2, Kathryn Henrikson

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CHARACTERIZATION OF OVARIAN TISSUE CULTURE AND INVESTIGATION OF EMBRYONIC RESPONSE TO TEMPERATURE STRESS USING A SHP2 PHOSPHATASE INHIBITOR IN CIONA INTESTINALIS, Rose Jacobson

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INVESTIGATING THE ROLE OF RIBOSOMAL PROTEIN US17 IN 30S RIBOSOMAL SUBUNIT ASSEMBLY, Kelly McManus

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MECHANISMS OF INTERACTION BETWEEN HAEMOPHILUS PARAINFLUENZAE AND STREPTOCOCCUS MITIS, Dasith Perera

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FUNCTIONAL ANALYSIS OF VIRULENCE IN VIBRIO CORALLIILYTICUS RE22 AND PROBIOTIC MECHANISMS OF PHAEOBACTER INHIBENS S4, Christian W. Schuttert

Theses/Dissertations from 2020

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INVESTIGATING THE INHIBITORY PROPERTIES OF CANDIDATE PROBIOTICS TOWARDS VIBRIO PARAHAEMOLYTICUS, Jacqueline Hilary Camm

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CELL CYCLE-REGULATION OF THE FANCD2 PROTEIN VIA CDK-MEDIATED S592 PHOSPHORYLATION, Juan A. Cantres-Velez

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REGULATING QUIESCENCE AND DIVISION IN ESCHERICHIA COLI, Eric Charles DiBiasio

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FUNCTION AND VARIABILITY OF METABOLIC NETWORKS, Keith Dufault-Thompson

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DETERMINING IMPACTS OF IRON LIMITATION ON DIATOM CHLOROPLAST METABOLISM AND PHYSIOLOGY, Kristofer Gomes

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THE BIOGEOGRAPHY OF ANTARCTIC MARINE DIATOMS AND THEIR RESPONSE TO VARIED IRON CONCENTRATIONS, Laura Z. Holland

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THE DEVELOPMENT AND EVALUATION OF TRANSGENIC SORGHUM LINES FOR CONFERRED PHENOTYPES, Jiayin Liu

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MODULATION OF RECEPTOR INTERACTING PROTEIN KINASE 1 (RIPK1) SIGNALING DURING DENGUE VIRUS INFECTION, Darshika Jeewanthi Udawatte

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INVESTIGATING THE STRUCTURE AND FUNCTION OF A NOVEL ANTI-VIRULENCE FACTOR, Jamie Wandzilak

Theses/Dissertations from 2019

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MECHANISMS OF DIVISION SITE SELECTION AND ROLE OF THE ATP-DEPENDENT PROTEASE CLPXP IN MIND REGULATION AND PROTEOSTASIS IN E. COLI, Christopher James LaBreck

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POPULATION GENETIC STRUCTURE OF SARDINELLA AURITA AND SARDINELLA MADURENSIS IN THE EASTERN CENTRAL ATLANTIC REGION (CECAF) IN WEST AFRICA, Evelyn Takyi

Theses/Dissertations from 2018

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CHARACTERIZING THE FUNCTIONAL ROLE AND REGULATED ASSEMBLY OF PROTEIN POLYMERS MIND AND FTSA DURING ESCHERICHIA COLI CELL DIVISION, Joseph Jake Conti

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Isolation and Identification of Probiotic Bacteria for the Management of Epizootic Shell Disease, Grace Underwood

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THALASSIOSIROID DIATOM RESPONSES TO SILICON STRESS AND OCEAN ACIDIFICATION, Joselynn Wallace

Theses/Dissertations from 2017

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High Throughput and Mechanistic Analysis of the HRD Motif of Src Protein Tyrosine Kinase, Yixin Cui

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Biocontrol of Acute Hepatopancreatic Necrosis Disease (AHPND), Jason LaPorte

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Characterization of a H4K20ME2 Methyl-Binding Domain in the Fanconi Anemia Protein FANCD2, Karissa Lynn Paquin

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The Effects of TCA Cycle Mutations on the Virulence of Vibrio Aguillarum Strains M93SM and NB10SM, Edward Spinard

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Insights Into Chromatin Modification and FANCD2 Phosphorylation in DNA Damage Repair, David Vierra II

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Direct Substrate Recognition by the ATP-Dependent Chaperone Protease CLPXP and Roles in Proteostasis, Marissa Grace Viola

Theses/Dissertations from 2016

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Development and Validation of Immunoinformatics Tools for Swine Vaccine Development, Andres H. Guiérrez Núñez

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Characterizing Alternative Polyadenylation in Male Germ Cells Using Poly(A)-seq, Holly Tran

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Characterization of the Role of the Phosphatase and Tensin Homolog, PTEN, in DNA Crosslink Repair, Elizabeth Ann Vuono

Theses/Dissertations from 2015

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Further Insights Into the Regulation of the Fanconi Anemia FANCD2 Protein, Rebecca Anne Boisvert

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Characterization of Biofilm Formation, Chemotaxis, and the Genome of Aliiroseovarius crassostreae, Linda Kessner

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An Investigation of the Interactions Between Escherichia coli and the Intestinal Microbiota In Vivo and In Vitro, Matthew E. Mokszycki

Theses/Dissertations from 2014

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DELETION OF ANTIBODY ENCODED TOLEROGENIC SIGNALS TO IMPROVE A DENDRITIC CELL TARGETED VACCINE DELIVERY PLATFORM SYSTEM, Danielle Aguirre

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INVESTIGATION OF GENES CONTRIBUTING TO WHOLE PLANT SENESCENCE IN SOYBEAN (GLYCINE MAX), Robert Almeida

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IDENTIFICATION OF NOVEL FANCD2 INTERACTING PROTEINS VIA IMMUNOPRECIPITATION AND MASS SPECTROMETRY, Paul A. Azzinaro

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Novel Strategies for the Purification and Inhibition of Protein-Tyrosine Kinases, Alexander Brown IV

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ELUCIDATING THE MOLECULAR RESPONSE OF MICROBIAL NITROGEN FIXATION IN ESTUARINE SEDIMENTS TO HYPOXIA, Andraya Louise Ehrlich

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DEVELOPING AND OPTIMIZING A METHOD TO ANALYZE SUBSTRATE SPECIFICITY OF TYROSINE KINASES, Ralph Kfoury

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STRUCTURE, FUNCTION AND EVOLUTION OF PHOSPHOPROTEIN P0 AND ITS UNIQUE INSERT IN TETRAHYMENA THERMOPHILA, Giovanni Pagano

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FUNCTIONAL ANALYSIS OF THE CELLULOSE SYNTHASE CLASS SPECIFIC REGION IN PHYSCOMITRELLA PATENS, Tess Scavuzzo-Duggan

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CHARACTERIZATION OF THE PROBIOTIC MECHANISM OF PHAEOBACTER GALLAECIENSIS S4 AGAINST BACTERIAL PATHOGENS, Wenjing Zhao

Theses/Dissertations from 2013

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MODIFICATION OF THE ESCHERICHIA coli NISSLE 1917 envZ GENE TO IMPROVE ITS PROBIOTIC POTENTIAL, Jimmy Adediran

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Identification of Salivary Antigens from the Deer Tick Ixodes Scapularis as Novel Vaccine Candidates, Martin Becker

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EFFECTS OF POSITION AND ORIENTATION ON PAX6 UPSTREAM ENHANCERS IN CIONA INTESTINALIS, Thomas Andrew Bregnard

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Using Molecular Tools to Elucidate Controls on Microbes Driving the Nitrogen Cycle in Marine Sediments, Shelley Marie Brown

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REGULATION OF HEMOLYSIN GENE EXPRESSION AND THE EFFECTS OF METABOLISM MUTATIONS ON THE VIRULENCE OF VIBRIO ANGUILLARUM, Xiangyu Mou

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GLUCONEOGENESIS AND COLONIZATION OF THE MOUSE INTESTINE BY E. COLI EDL933 AND E. COLI NISSLE 1917, Silvia Anna Christina Schinner

Theses/Dissertations from 2012

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SYNTHESIS AND BIOASSAY OF NOVEL HYBRID ANTIMICROBIAL PEPTIDES (AMPS), DESIGNED TO INCREASE THERAPEUTIC ACTIVITY AND DECREASE HEMOLYSIS, David E. Ryder

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Characterization of Maize Sex-Determination Gene Orthologs in Rice (Oryza Sativa L. Japonica Cv. Nipponbare), John Ventura

Theses/Dissertations from 2004

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Regulation of cra, A Regulatory Gene of Glycolytic and Gluconeogenic Pathways in Salmonella enterica serovar Typhimurium, James H. Allen

Theses/Dissertations from 1996

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Molecular Genetic Analysis of Senescence and the Reversal of Senescence in Soybean Cotyledons [Glycine max (L.) Bass], Normand Edouard Allaire

Theses/Dissertations from 1983

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Some Aspects of the Effects of Heavy Metal Pollution on Microbal Sediment Populations, Steven Arcidiacono

Theses/Dissertations from 1982

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The Monitoring of Clostridium perfringens Spore Density in Bottom Sediments and It's Applications, David J. Emerson

Theses/Dissertations from 1980

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Correlation of In Vitro Chemotaxis with In Vitro Virulence of Bacteroides Fragilis Products, Stephen Atsekhagbo Adamu

Theses/Dissertations from 1954

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VI Typhoid Flagellar and Heterophile Antibodies in Serums of Children, Peter Paul Antosia