Document Type
Article
Date of Original Version
2014
Department
Biomedical and Pharmaceutical Sciences
Abstract
The formation of well-ordered nanostructures through self-assembly of diverse organic and inorganic building blocks has drawn much attention owing to their potential applications in biology and chemistry. Among all organic building blocks, peptides are one of the most promising platforms due to their biocompatibility, chemical diversity, and resemblance with proteins. Inspired from the protein assembly in biological systems, various self-assembled peptide structures have been constructed using several amino acids and sequences. This review focuses on this emerging area, the recent advances in peptide self-assembly, and formation of different nanostructures, such as tubular, fibers, vesicles, spherical, and red coil structures. While different peptide nanostructures are discovered, potential applications will be explored in drug delivery, tissue engineering, wound healing, and surfactants.
Citation/Publisher Attribution
Mandal, D., Shirazi, A. N., & Parang, K. (2014). Self-assembly of peptides to nanostructures. Organic & Biomolecular Chemistry, 12, 1-57. doi: 10.1039/C4OB00447G
Available at: http://dx.doi.org/10.1039/C4OB00447G
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This is a pre-publication author manuscript of the final, published article.
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