Date of Award
Master of Science in Pharmaceutical Sciences
Objective: To determine the predictors of concomitant use of benzodiazepines with chronic opioid use in Rhode Island using pharmacy level data.
Design: Cross – sectional analysis
Setting: Rhode Island Prescription Drug Monitoring Program (PDMP) Database, 2015
Participants: Any person who filled a prescription for an opioid (>30 days’ supply), a benzodiazepine or both at a licensed retail pharmacy in Rhode Island during 2015.
Main outcome measure: Concomitant use of opioid analgesics and benzodiazepines, defined as the receipt of any benzodiazepine and opioid pharmacy dispensing having a days’ supply which overlaps by at least 1 day.
Results: Of 139,410 patients who were included in our analysis, 15.5% had overlapping (concomitant) opioid and benzodiazepine prescriptions during 2015. Patients who were younger than 45 years of age, and who see more than three prescribers were less likely to be prescribed both opioids and benzodiazepines, in which the days supply overlap. Additionally, each additional prescription a person receives for a controlled substance increased the odds that they were prescribed concomitant therapy.
Patry, Emily, "Predictors of Concomitant Use of Prescription Opiods and Benzodiazepines in Rhode Island" (2018). Open Access Master's Theses. Paper 1189.