Evaluating nicotine replacement therapy and stage-based therapies in a population-based effectiveness trial
Date of Original Version
Pharmacological interventions for smoking cessation are typically evaluated using volunteer samples (efficacy trials) but should also be evaluated in population-based trials (effectiveness trials). Nicotine replacement therapy (NRT) alone and in combination with behavioral interventions was evaluated on a population of smokers from a New England Veterans Affairs Medical Center. Telephone interviews were completed with 3,239 smokers, and 2,054 agreed to participate (64%). Participants were randomly assigned to one of four conditions: stage-matched manuals (MAN); NRT plus manuals (NRT + MAN); expert system plus NRT and manuals (EXP + NRT + MAN); and automated counseling plus NRT, manuals, and expert system (TEL + EXP + NRT + MAN). Assessments were completed at baseline, 10, 20, and 30 months. The point prevalence cessation rates at final follow-up (30 months) were MAN, 20.3%; NRT + MAN, 19.3%; EXP + NRT + MAN, 17.6%; and TEL + EXP + NRT + MAN, 19.9%. Stage-matched manuals provided cessation rates comparable with previous studies. The addition of NRT, expert system interventions, and automated telephone counseling failed to produce a further increase in intervention effectiveness. © 2006 APA, all rights reserved.
Journal of Consulting and Clinical Psychology
Velicer, Wayne F., Robert H. Friedman, Joseph L. Fava, Suzy B. Gulliver, Stefan Keller, Xiaowu Sun, Harley Ramelson, and James O. Prochaska. "Evaluating nicotine replacement therapy and stage-based therapies in a population-based effectiveness trial." Journal of Consulting and Clinical Psychology 74, 6 (2006): 1162-1172. doi:10.1037/0022-006X.74.6.1162.