Title

Changing trends in antihypertensive therapy in two New England communities during the 1980s

Document Type

Article

Date of Original Version

1-1-1993

Abstract

The prevalence rates and correlates of antihypertensive drug use among individuals with hypertension were determined using data derived from five biennial population-based surveys conducted between 1981 and 1990 in two New England communities. Point prevalence estimates were determined for nine categories of antihypertensive agents at five time points, and were analyzed by age and sex using multiple logistic regression. In the first cross- sectional survey, the prevalence of use per 1000 individuals with hypertension was 235.4 for diuretics, 57.1 for β-blockers, 65.5 for combination products, 29.2 for central α-agonists, 2.8 for peripheral α- antagonists, and 8.4 each for adrenergic blockers and direct vasodilators. The prevalence rates for calcium channel blockers and angiotensin-converting enzyme inhibitors increased sharply between the third and fourth survey cycles. Significant age- and sex-related differences in antihypertensive use were detected.

Publication Title

Pharmacotherapy

Volume

13

Issue

3

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