Weighing in: Emergent diabetes mellitus and second-generation antipsychotics
Date of Original Version
Of all the metabolic effects of some of the atypical second-generation antipsychotics, their potential to induce glucose dysregulation has induced a storm of controversy over the past several years. The numerous published epidemiologic studies are difficult to interpret due to the high background rate of type 2 diabetes mellitus in this population, the inherent problems with analysis of observational data, and the short duration of the available studies. A plan to monitor for weight gain, hypertriglyceridemia, glucose dysregulation, and other potential adverse metabolic effects resulting from antipsychotic treatment is critical.
Annals of Pharmacotherapy
Dufresne, Robert L.. "Weighing in: Emergent diabetes mellitus and second-generation antipsychotics." Annals of Pharmacotherapy 41, 10 (2007): 1725-1727. doi:10.1345/aph.1K362.