Title

DETERMINATION OF LEFT VENTRICULAR PRESSURE-VOLUME RELATIONS WITH A COMPUTER BASED CADMIUM TELLURIDE CARDIAC PROBE.

Document Type

Conference Proceeding

Date of Original Version

1-1-1980

Abstract

A computer controlled nonimaging cadmium-telluride cardiac probe (dia equals 1. 6cm) was developed and used with a micromanometer tipped cardiac catheter to obtain continuous measurements of left ventricular (LV) pressure-volume relations. The subjects' red blood cells were labeled with technetium-99m and an average LV time activity curve (10mSEC resolution) computed from a 10 sec data acquisition. Pressure count-rate loops for an average cardiac cycle were computed after filtering the nuclear data to 4. 8 Hz. Ejection fractions (EF) measured by the probe correlated well with EF's obtained from LV cineangiograms in 4 animals. In addition probe EF's also correlated well with EF's obtained with a gamma camera computer system in 19 humans with a variety of cardiac disorders. In three animals the LV minor axis was measured by implanted sonographic length sensors. Changes in pressure-length loops correlated well with the simultaneously measured changes in pressure-count rate loops over a wide range of hemodynamic conditions. Thus the system should be a useful research and clinical application.

Publication Title

Computers in Cardiology

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