Hemodynamic effects of new intra-aortic balloon counterpulsation timing methods in patients: A multicenter evaluation
Date of Original Version
Background: To test whether later intra-aortic balloon pump (IABP) deflation approaching or simultaneous with left ventricular ejection would improve hemodynamics and myocardial efficiency with the use of new balloon deflation methods, 4 IABP timing techniques were evaluated in 43 patients. Methods and Results: Later balloon deflation produced significantly greater percentage changes in mean aortic pressure (6% vs 1%), systolic pressure time index (-27% vs -20%), diastolic pressure time index (35% vs 19%), and the systolic pressure-time index/diastolic pressure-time index ratio (97% vs 51%), respectively. However, these changes increased peak systolic pressure (-15% vs -11%). Cardiac output and stroke volume indexes were not significantly altered over the 4 settings. Conclusions: These data suggest that systemic hemodynamics and myocardial efficiency may be improved by later balloon deflation approaching left ventricular ejection in comparison to conventional IABP timing.
American Heart Journal
Kern, Morton J., Frank V. Aguirre, Eugene A. Caracciolo, Richard G. Bach, Thomas J. Donohue, David Lasorda, E. M. Ohman, Robert N. Schnitzler, Donald L. King, William J. Ohley, and Joseph Grayzel. "Hemodynamic effects of new intra-aortic balloon counterpulsation timing methods in patients: A multicenter evaluation." American Heart Journal 137, 6 (1999): 1129-1136. doi:10.1016/S0002-8703(99)70373-X.