Date of Original Version
A new approach for the direct amination of 2-phenylpyridine derivatives using a diphthalimide-iodane and copper triflate has been developed. A series of different 2-phenylpyridine derivatives were aminated with yields up to 88%. Mechanistic investigations indicate that the reaction proceeds via a copper-mediated single electron transfer.
Kantak, A. A., Marchetti, L., & DeBoef, B. (2015). Regioselective C–H bond amination by aminoiodanes. Chemical Communications, 51(17), 3574-3577. doi: 10.1039/C4CC10246K
Available at: http://dx.doi.org/10.1039/C4CC10246K