Date of Award
Master of Science in Computer Science
Computer Science and Statistics
Protein structure largely determines functionality; three-dimensional structural alignment is thus important to analysis and prediction of protein function. Protein Local Alignment Tool (PLAT) is an implementation of a web-based tool with a graphic interface that performs local protein structure alignment based on user-selected amino acids. Global alignment compares entire structures; local alignment compares parts of structures. Given input from the user and the RCSB Protein Data Bank, PLAT determines an optimal translation and rotation that minimizes the distance between the structures defined by the selected inputs.
Jaegle, Stephen H., "Plat: A Web Based Protein Local Alignment Tool" (2017). Open Access Master's Theses. Paper 1080.