Depth sensitivity improvement of region-of-interest diffuse optical tomography from superficial signal regression

Manob Jyoti Saikia, Indian Institute of Science
Rakesh Manjappa, University of Rhode Island
Kunal Mankodiya, Indian Institute of Science
Rajan Kanhirodan, University of Rhode Island


We report depth sensitivity enhancement of a region-of-interest optical tomographic system. Two optode configurations, 25 and 50 mm separations are used to construct a noise model. A regression technique isolates the functional activity of deep tissue layer.