Zika virus: The agent and its biology, with relevance to pathology
Date of Original Version
Once obscure, Zika virus (ZIKV) has attracted significant medical and scientific attention in the past year because of large outbreaks associated with the recent introduction of this virus into the Western hemisphere. In particular, the occurrence of severe congenital infections and cases of Guillain-Barre syndrome has placed this virus squarely in the eyes of clinical and anatomic pathologists. This review article provides a basic introduction to ZIKV, its genetics, its structural characteristics, and its biology. A multidisciplinary effort will be essential to establish clinicopathologic correlations of the basic virology of ZIKV in order to advance development of diagnostics, therapeutics, and vaccines.
Publication Title, e.g., Journal
Archives of Pathology and Laboratory Medicine
Medin, Carey L., and Alan L. Rothman. "Zika virus: The agent and its biology, with relevance to pathology." Archives of Pathology and Laboratory Medicine 141, 1 (2017): 33-42. doi: 10.5858/arpa.2016-0409-RA.