Date of Original Version
Reported herein is the development of non-covalent, proximity-induced energy transfer from small-molecule toxicants to organic fluorophores bound in the cavity of γ-cyclodextrin. This energy transfer occurs with exceptional efficiency for a broad range of toxicants in complex biological media, and is largely independent of the spectral overlap between the donor and acceptor. This generally applicable phenomenon has significant potential in the development of new turn-on detection schemes.
Serio, N., Chanthalyma, C., Prignano, L, & Levine, M. (2014). Cyclodextrin-promoted energy transfer for broadly applicable smallmolecule detection. Supramolecular Chemistry, 26(10-12), 714-721. doi: 10.1080/10610278.2013.860226
Available at: http://dx.doi.org/10.1080/10610278.2013.860226