Title

Microwave assisted vacuum drying and end point determination using mass spectrometry, Part I

Document Type

Article

Date of Original Version

11-1-2004

Abstract

On-line mass spectrometry (MS) was investigated as a tool to monitor microwave vacuum drying operations on laboratory scale. Using several different solvents and calcium carbonate solids, MS was used to monitor the drying end point of single and multiple solvent wet cakes. The microwave drying rates for polar solvents were shown to have a linear correlation with solvent heat of vaporization. Mass spectrometry profiles were also shown to correlate with other drying end point parameters, including rate of recovered solvent, product temperature, and microwave reflected power.

Publication Title

Organic Process Research and Development

Volume

8

Issue

6

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