Fluvirosaones A and B, Two Indolizidine Alkaloids with a Pentacyclic Skeleton from Flueggea virosa
Date of Original Version
Fluvirosaones A (1) and B (2), together with virosecurinine (3), were isolated from Flueggea virosa. Their structures were determined by physical, spectroscopic, and X-ray analysis and confirmed through comparison of the calculated and experimental 13C NMR and electronic circular dichroism (ECD) data. Compounds 1 and 2 represent the first examples of a pentacyclic Securinega alkaloid containing a pentacyclic system and an α,β-unsaturated ketone. Plausible biogenetic pathways of compounds 1 and 2 are proposed.
Luo, Xiang Kun, Jie Cai, Zhi Yong Yin, Pan Luo, Chan Juan Li, Hang Ma, Navindra P. Seeram, Qiong Gu, and Jun Xu. "Fluvirosaones A and B, Two Indolizidine Alkaloids with a Pentacyclic Skeleton from Flueggea virosa." Organic Letters 20, 4 (2018): 991-994. doi:10.1021/acs.orglett.7b03935.