Date of Award


Degree Type


Degree Name

Master of Science (MS)


Pharmaceutical Sciences

First Advisor

Cynthia Willey


HPV vaccination is routinely recommended for young adult women aged 18-26 regardless of previous sexual activity or history of HPV-related disease. As of 2010, only 21% of US women had received ≥1 doses of HPV vaccine. The objective of this study was to describe United States (US) women aged 18-26 who do not initiate vaccination and identify a minimum subset of variables to develop a predictive model of non-vaccination. Data from the 2010 National Health Interview Survey Adult Cancer Supplement were used to examine US women aged 18-26 (N=1,866). Descriptive statistics, univariate procedures, and multivariate logistic regression were conducted. Results indicate that 78% of eligible women did not receive vaccination, and 35% of unvaccinated women were not aware of the vaccine. Eight variables were retained for the final model (age aOR=2.93, 95% CI=2.00, 4.30; marital status aOR=1.75, 95% CI=1.02, 3.01; live birth in the past 5 years aOR=2.77, 95% CI=1.75, 4.39, current birth control use aOR=0.45, 95% CI=0.31, 0.64; region aOR=0.50, 95% CI=0.31, 0.79; recent doctor’s visit aOR=0.45, 95% CI=0.39-0.84; flu shot receipt aOR=0.36, 95% CI=0.24, 0.54; tetanus shot receipt aOR=0.40, 95% CI=0.26, 0.62). This model showed good fit to the data (Hosmer-Lemeshow chi-square=14.41(8); p=0.07; max rescaled R-square=0.27; c statistic=0.80). These findings show that older age, being married, having children, living in the South, and not receiving other preventive health services are associated with non-vaccination. These findings identify a subgroup of at-risk women who might benefit from targeted vaccine promotion campaigns to increase HPV vaccine uptake.