Date of Award

2017

Degree Type

Dissertation

Degree Name

Doctor of Philosophy in Nursing

Department

Nursing

First Advisor

Mary C. Sullivan

Abstract

Little is known about the psychobiological processes of adults, at age 23 who were born prematurely. Compared to infants born at term, premature infants face additional obstacles of immature body systems, more neonatal stress and are at risk for developmental delay and possible parental overprotective patterns. The Developmental Origins of Health and Disease theory asserts that early prenatal and neonatal stress disturbs hypothalamic-pituitary-adrenal (HPA) axis function, which in the long run, affects later health and behavior. The purpose of this secondary analysis is to examine neonatal stress of prematurity on coping, emotional intelligence, physiological responses, developmental milestones and emotional health at age 23 years in a sample at risk for HPA dysfunction.

Prematurely born age 23 year olds, categorized into four groups of medical risk were compared to a term-born group on measures of: Daily Hassles Stress, Coping Response Inventory-Adult, Bar-On EQi, Adult Self Report and salivary cortisol responses in the Trier Social Stress Test. Significant differences in cortisol slope, between the term and premature medical risk group with high stress coupled with lower and upper socioeconomic status, were found as well as differences in total cortisol AUCg levels between premature groups. Significant differences in cortisol slope values were found for all 23 year olds with Adult Self Report psychological clinical problems. This study supports the HPA Axis stress response as a biomarker of premature birth and of psychological clinical problems. Preventative and clinical interventions for young adults to reduce and actively manage problems can promote adaptive emotional health behaviors and later physical health.

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.