Applications of multicomponent analysis and fiber optic in un-visible, near and mid infrared spectroscopy

Chi-Shi Chen, University of Rhode Island

Abstract

Several applications of spectroscopic methods employing fiber-optic probes or sensors to improve sample handling techniques and applying multivariate data processing algorithms to spectral processing have been investigated. Spectral reduction, calibration and modeling of the absorbance data are evaluated as means for both quantitative and qualitative applications. It is possible to determine chemical components of a mixture, simultaneously, by taking advantage of differences in the shape of their absorption spectra.^ Ultraviolet and near-infrared spectroscopic multicomponent analysis employing fiber optics to carry the light to and from the area of measurement have been demonstrated for drug dissolution process monitoring, glucose biosensor and calibration transfer. The fiber optics link between the instrument and measurement areas is intrinsically safe, free from electromagnetic interference. It is also quite easy to multiplex several fiber-optic probe to a single spectrophotometer that spectrometer receives its light from different point in the process. All of these factors make real-time, in situ monitoring much simpler than it has been in the past.^ A pattern recognition algorithm, Mix-Match search, has been modified to function as a nondestructive analysis technique for identification dyes and fabric fibers in dyed textiles. It was successfully used to identify the components of several dyed textiles. This new method saves time and materials in comparison with traditional methods of analyzing archaeological textiles for identity dyes and textile fibers. This algorithm also has been demonstrated to search a mid-infrared library of 1,021 solid and liquid compounds with two-and three-component mixtures. The major advantage of this algorithm is its ability to identify components in mixture without any prior knowledge of the compositions. Data processing based on the use of Fourier transform improved the searching performance on poor quality spectra and on spectra measured with different spectrometer systems. ^

Subject Area

Chemistry, Analytical

Recommended Citation

Chi-Shi Chen, "Applications of multicomponent analysis and fiber optic in un-visible, near and mid infrared spectroscopy" (1995). Dissertations and Master's Theses (Campus Access). Paper AAI9601837.
http://digitalcommons.uri.edu/dissertations/AAI9601837

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