Modern Apparatus for Performing Flash Chromatography: An Experiment for the Organic Laboratory

Authors

Gregory R. Naumiec, University of Rhode Island
Angela N. Del Padre, University of Rhode Island
Matthew M. Hooper, University of Rhode Island
Alison St. Germaine, University of Rhode Island
Brenton DeBoef, University of Rhode IslandFollow

Document Type

Article

Date of Original Version

2013

Department

Chemistry

Abstract

A modern apparatus for performing flash chromatography using commercially available, prepacked silica cartridges has been developed. The key advantage of this system, when compared to traditional flash chromatography, is its use of commercially available silica cartridges, which obviates the need for students to handle silica gel. The apparatus has been tested for its ability to perform separations that are commonly found in organic chemistry teaching laboratories, and a laboratory module that combines the techniques of thin-layer chromatography, gas chromatography, and flash chromatography is described. The performance of this new chromatography apparatus was comparable to a traditional flash chromatography column.

Citation/Publisher Attribution

Naumiec, G. R., Del Padre, A. N., Hooper, M. M., St. Germaine, A. & DeBoef, B. (2013). A Modern Apparatus for Performing Flash Chromatography: An Experiment for the Organic Laboratory. Journal of Chemical Education, 90(3), 376-378. doi: 10.1021/ed300360f

Available at: http://dx.doi.org/10.1021/ed300360f