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We introduce the construction of MEWMA (Multivariate exponentially weighted movingaverage) process control in the field of bio surveillance. Such introduction will both improve the reliability of data collected in bio surveillance, better interpretation of the results,improvement in the quality of results and standardization of results when more than two variables are involved. We propose sensitivity ratios as a measure of the effects of the mean shift and dispersion shift in processes under study. Using these sensitivity measures, we designed the optimal exponential weighting factor, which is consistent to results reported in control chart applications. Although ARL (average run length) is the usual measure for control chart performance in multivariate process control, it is by no means the only criterion, however, at the moment it is most widely used criterion for decision making. We suggest addition study of other criteria. For example Medial Run Length, Days to Completion, Direction of Eorrors and others.